6576-05-2

• 常用中文名：1-(4-氟苯基)-2-(4-吡啶基)乙酮
• 常用英文名：1-(4-Fluorophenyl)-2-(pyridin-4-yl)ethanone
• CAS号：6576-05-2
• 分子式：C₁₃H₁₀FNO
• 分子量：215.223
• 发布时间：2018-12-25 13:19:59
• 更新时间：2024-01-16 22:07:15

名称

• 中文名: 1-(4-氟苯基)-2-(4-吡啶基)乙酮
• 英文名: 1-(4-fluorophenyl)-2-pyridin-4-ylethanone
• 中文别名: 1-(4-氟苯基)-2-吡啶-4-基-乙酮
• 英文别名: 1-(4-fluorophenyl)-2-(pyridine-4-yl)ethanone; 1-(4-Fluorophenyl)-2-(4-pyridinyl)ethanone; 1-(4-fluorophenyl)-2-(pyridin-4-yl)-ethanone; 1-(4-Fluorophenyl)-2-(pyridin-4-yl)ethanone; 1-(4-FLUOROPHENYL)-2-(4-PYRIDYL)ETHANONE; 1-fluoro-4-(4'-pyridylacetyl)benzene; Ethanone, 1-(4-fluorophenyl)-2-(4-pyridinyl)-; 4-(2'-(4''-fluorophenyl)-2'-oxoethyl)pyridine; 1-(4-Fluorophenyl)-2-pyridin-4-yl-ethanone; 1-(4-fluorophenyl)-2-(pyridin-4-yl)-ethan-1-one; 1-(4-fluorophenyl)-2-(pyridin-4-yl)-1-ethanone; 4-FLUOROPHENYL-4-PYRIDYLMETHYL KETONE

物化性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 362.6±22.0 °C at 760 mmHg
• 分子式: C₁₃H₁₀FNO
• 分子量: 215.223
• 闪点: 173.1±22.3 °C
• 精确质量: 215.074646
• PSA: 29.96000
• LogP: 1.74
• 蒸汽压: 0.0±0.8 mmHg at 25°C
• 折射率: 1.571
• 储存条件: 2-8°C

安全

• 危害码 (欧洲): Xi

合成路线

108-89-4 451-46-7 ~98% 6576-05-2

文献：Rupert, Kenneth C.; Henry, James R.; Dodd, John H.; Wadsworth, Scott A.; Cavender, Druie E.; Olini, Gilbert C.; Fahmy, Bohumila; Siekierka, John J. Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 3 p. 347 - 350

116332-54-8 ~99% 6576-05-2

文献：J. URIACH Y COMPANIA S.A. Patent: WO2004/76450 A1, 2004 ; Location in patent: Page 37-38 ; WO 2004/076450 A1

325770-31-8 108-89-4 ~67% 6576-05-2

文献：Takeda Chemical Industries, Ltd. Patent: EP1402900 A1, 2004 ;

108-89-4 116332-54-8 ~97% 6576-05-2

文献：Seerden, Jean-Paul G.; Leusink-Ionescu, Gabriela; Leguijt, Robin; Saccavini, Catherine; Gelens, Edith; Dros, Bas; Woudenberg-Vrenken, Titia; Molema, Grietje; Kamps, Jan A.A.M.; Kellogg, Richard M. Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 5 p. 1352 - 1357

108-89-4 100-41-4 116332-54-8 ~% 6576-05-2

文献：US6528531 B1, ; US6432980 B1, ;

108-89-4 451-46-7 108-18-9 ~% 6576-05-2 详细

文献：US5109002 A1, ; US 5109002 A

403-43-0 ~% 6576-05-2

文献：Chemical and Pharmaceutical Bulletin, , vol. 53, # 4 p. 410 - 418

108-89-4 403-33-8 ~% 6576-05-2

文献：Bioorganic and Medicinal Chemistry Letters, , vol. 20, # 8 p. 2634 - 2638

456-22-4 ~% 6576-05-2

文献：Angewandte Chemie - International Edition, , vol. 52, # 33 p. 8551 - 8556 Angew. Chem., , vol. 125, # 33 p. 8713 - 8718,6

上下游产品

上游产品  9
108-89-4 451-46-7 116332-54-8 325770-31-8
100-41-4 108-18-9 403-43-0 403-33-8
456-22-4
下游产品  6
148671-39-0 216529-53-2 152121-30-7 166895-06-3
755753-82-3 87532-35-2