43076-30-8

• 常用中文名：特非那酮
• 常用英文名：4'-tert-butyl-4-[4-(hydroxybenzhydryl)piperidino]butyrophenone
• CAS号：43076-30-8
• 分子式：C₃₂H₃₉NO₂
• 分子量：469.65800
• 发布时间：2016-01-27 19:35:58
• 更新时间：2024-01-11 00:35:49

名称

• 中文名: 特非那酮
• 英文名: 1-(4-tert-butylphenyl)-4-[4-[hydroxy(diphenyl)methyl]piperidin-1-yl]butan-1-one
• 英文别名: EINECS 256-074-1; Terfenadinone; Terfenadine impurity A; terfenadone

物化性质

• 密度: 1.082g/cm3
• 沸点: 624.5ºC at 760 mmHg
• 分子式: C₃₂H₃₉NO₂
• 分子量: 469.65800
• 闪点: 331.5ºC
• 精确质量: 469.29800
• PSA: 40.54000
• LogP: 6.53300
• 折射率: 1.574

安全

• 海关编码: 2933399090

合成路线

1057648-42-6 115-46-8 ~27% 43076-30-8

文献：Holzer, Marcel; Ziegler, Sigrid; Albrecht, Beatrice; Kronenberger, Bernd; Kaul, Artur; Bartenschlager, Ralf; Kattner, Lars; Klein, Christian D.; Hartmann, Rolf W. Molecules, 2008 , vol. 13, # 5 p. 1081 - 1110

115-46-8 43076-61-5 ~69% 43076-30-8

文献：El Ouarradi, Amane; Salard-Arnaud, Isabelle; Buisson, Didier Tetrahedron, 2008 , vol. 64, # 51 p. 11738 - 11744

43076-61-5 ~% 43076-30-8

文献：Zhang; Ter Laak; Timmerman European Journal of Medicinal Chemistry, 1993 , vol. 28, # 2 p. 165 - 173

50679-08-8 ~% 43076-30-8

文献：Yang; Prakash; Roden; Snyders British Journal of Pharmacology, 1995 , vol. 115, # 2 p. 267 - 274

253185-03-4 ~% 43076-30-8

文献：Lafite, Pierre; Dijols, Sylvie; Buisson, Didier; Macherey, Anne-Christine; Zeldin, Darryl C.; Dansette, Patrick M.; Mansuy, Daniel Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 10 p. 2777 - 2780

上下游产品

上游产品  4
1057648-42-6 115-46-8 43076-61-5 50679-08-8
下游产品  2
50679-08-8 76811-98-8

海关

海关编码	2933399090
中文概述	2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%