86641-76-1

• 常用中文名：3,12-二(3-溴丙烷酰基)-3,12-二氮杂-6,9-二铵二螺[5.2.5.2]十六烷二氯化物
• 常用英文名：spirobromin
• CAS号：86641-76-1
• 分子式：C₁₈H₃₂Br₂Cl₂N₄O₂
• 分子量：567.18600
• 发布时间：2016-03-20 06:39:36
• 更新时间：2024-02-23 17:21:24

名称

• 中文名: 3,12-二(3-溴丙烷酰基)-3,12-二氮杂-6,9-二铵二螺[5.2.5.2]十六烷二氯化物
• 英文名: 3-bromo-1-[12-(3-bromopropanoyl)-3,12-diaza-6,9-diazoniadispiro[5.2.59.26]hexadecan-3-yl]propan-1-one,dichloride
• 英文别名: Spirobromin; Dibrospidium Chloride; chlorospirobromine; spirobromine

物化性质

• 分子式: C₁₈H₃₂Br₂Cl₂N₄O₂
• 分子量: 567.18600
• 精确质量: 564.02700
• PSA: 40.62000
• 储存条件: 室温，干燥，通风

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : HM1157000 CHEMICAL NAME : 3,12-Diaza-6,9-diazoniadispiro(5.2.5.2)hexadecane, 3,12-bis(3-bromo-1-oxopropyl)-, dichloride CAS REGISTRY NUMBER : 86641-76-1 LAST UPDATED : 198809 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C18-H32-Br2-N4-O2.2Cl MOLECULAR WEIGHT : 567.26 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 800 mg/kg TOXIC EFFECTS : Behavioral - tremor Behavioral - muscle weakness Lungs, Thorax, or Respiration - dyspnea REFERENCE : DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 9,121,1984 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 825 mg/kg TOXIC EFFECTS : Behavioral - tremor Behavioral - muscle weakness Lungs, Thorax, or Respiration - dyspnea REFERENCE : DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 9,121,1984 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1924 mg/kg TOXIC EFFECTS : Behavioral - tremor Behavioral - muscle weakness Lungs, Thorax, or Respiration - dyspnea REFERENCE : DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 9,121,1984

安全

• 危害码 (欧洲): Xi

合成路线

1589-04-4 15486-96-1 ~35% 86641-76-1

文献：Safonova, T. S.; Chernov, V. A.; Minakova, S. M.; Dorokhova, M. I.; Levkovskaya, L. G.; et al. Pharmaceutical Chemistry Journal, 1983 , vol. 17, # 5 p. 375 - 377 Khimiko-Farmatsevticheskii Zhurnal, 1983 , vol. 17, # 5 p. 626 - 629

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