479493-68-0

• 常用中文名：4-(2-chloro-6-morpholin-4-ylpyrimidin-4-yl)morpholine
• 常用英文名：4-(2-chloro-6-morpholin-4-ylpyrimidin-4-yl)morpholine
• CAS号：479493-68-0
• 分子式：C₁₂H₁₇ClN₄O₂
• 分子量：284.74200
• 发布时间：2016-11-05 06:22:03
• 更新时间：2025-08-25 18:06:39

名称

• 英文名: 4-(2-chloro-6-morpholin-4-ylpyrimidin-4-yl)morpholine
• 英文别名: 4,6-dimorpholino-2-chloropyrimidine

物化性质

• 分子式: C₁₂H₁₇ClN₄O₂
• 分子量: 284.74200
• 精确质量: 284.10400
• PSA: 50.72000
• LogP: 0.93320

合成路线

110-91-8 3764-01-0 ~6% 10244-24-3 52127-83-0 详细

文献：NOVARTIS VACCINES AND DIAGNOSTICS, INC. Patent: WO2008/98058 A1, 2008 ; Location in patent: Page/Page column 57-58 ; WO 2008/098058 A1

3764-01-0 ~7% 10244-24-3 479493-68-0

文献：Burger, Matthew T.; Pecchi, Sabina; Wagman, Allan; Ni, Zhi-Jie; Knapp, Mark; Hendrickson, Thomas; Atallah, Gordana; Pfister, Keith; Zhang, Yanchen; Bartulis, Sarah; Frazier, Kelly; Ng, Simon; Smith, Aaron; Verhagen, Joelle; Haznedar, Joshua; Huh, Kay; Iwanowicz, Ed; Xin, Xiaohua; Menezes, Daniel; Merritt, Hanne; Lee, Isabelle; Wiesmann, Marion; Kaufman, Susan; Crawford, Kenneth; Chin, Michael; Bussiere, Dirksen; Shoemaker, Kevin; Zaror, Isabel; Maira, Sauveur-Michel; Voliva, Charles F. ACS Medicinal Chemistry Letters, 2011 , vol. 2, # 10 p. 774 - 779

110-91-8 3764-01-0 ~% 10244-24-3 479493-68-0

文献：NOVARTIS AG Patent: WO2007/84786 A1, 2007 ; Location in patent: Page/Page column 123 ; WO 2007/084786 A1

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