4-(2-chloro-6-morpholin-4-ylpyrimidin-4-yl)morpholine

Modify Date: 2024-01-10 12:40:15

4-(2-chloro-6-morpholin-4-ylpyrimidin-4-yl)morpholine Structure
4-(2-chloro-6-morpholin-4-ylpyrimidin-4-yl)morpholine structure
Common Name 4-(2-chloro-6-morpholin-4-ylpyrimidin-4-yl)morpholine
CAS Number 479493-68-0 Molecular Weight 284.74200
Density N/A Boiling Point N/A
Molecular Formula C12H17ClN4O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name 4-(2-chloro-6-morpholin-4-ylpyrimidin-4-yl)morpholine
Synonym More Synonyms

 Chemical & Physical Properties

Molecular Formula C12H17ClN4O2
Molecular Weight 284.74200
Exact Mass 284.10400
PSA 50.72000
LogP 0.93320

 Synthetic Route

~6%

Detail
Literature: NOVARTIS VACCINES AND DIAGNOSTICS, INC. Patent: WO2008/98058 A1, 2008 ; Location in patent: Page/Page column 57-58 ; WO 2008/098058 A1

~7%

4-(2-chloro-6-morpholin-4-ylpyrimidin-4-yl)morpholine Structure

4-(2-chloro-6-m...

CAS#:479493-68-0

Literature: Burger, Matthew T.; Pecchi, Sabina; Wagman, Allan; Ni, Zhi-Jie; Knapp, Mark; Hendrickson, Thomas; Atallah, Gordana; Pfister, Keith; Zhang, Yanchen; Bartulis, Sarah; Frazier, Kelly; Ng, Simon; Smith, Aaron; Verhagen, Joelle; Haznedar, Joshua; Huh, Kay; Iwanowicz, Ed; Xin, Xiaohua; Menezes, Daniel; Merritt, Hanne; Lee, Isabelle; Wiesmann, Marion; Kaufman, Susan; Crawford, Kenneth; Chin, Michael; Bussiere, Dirksen; Shoemaker, Kevin; Zaror, Isabel; Maira, Sauveur-Michel; Voliva, Charles F. ACS Medicinal Chemistry Letters, 2011 , vol. 2, # 10 p. 774 - 779

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4-(2-chloro-6-morpholin-4-ylpyrimidin-4-yl)morpholine Structure

4-(2-chloro-6-m...

CAS#:479493-68-0

Literature: NOVARTIS AG Patent: WO2007/84786 A1, 2007 ; Location in patent: Page/Page column 123 ; WO 2007/084786 A1

 Precursor & DownStream

Precursor  2

DownStream  0

 Synonyms

4,6-dimorpholino-2-chloropyrimidine