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175278-35-0

175278-35-0结构式

常用中文名：4-羟基-8-(三氟甲氧基)喹啉-3-羧酸乙酯
常用英文名：Ethyl 4-hydroxy-8-(trifluoromethoxy)quinoline-3-carboxylate
CAS号：175278-35-0
分子式：C₁₃H₁₀F₃NO₄
分子量：301.218
发布时间：2018-10-07 10:59:22
更新时间：2024-07-18 12:20:55

中文名	4-氧代-8-(三氟甲氧基)-1,4-二氢喹啉-3-羧酸乙酯
英文名	ethyl 4-oxo-8-(trifluoromethoxy)-1H-quinoline-3-carboxylate
英文别名	Ethyl 4-hydroxy-8-(trifluoromethoxy)quinoline-3-carboxylate ETHYL 4-OXO-8-(TRIFLUOROMETHOXY)-1,4-DIHYDROQUINOLINE-3-CARBOXYLATE Ethyl 4-hydroxy-8-(trifluoromethoxy)-3-quinolinecarboxylate 4-Hydroxy-8-trifluoromethoxyquinoline-3-carboxylic acid ethyl ester 3-Quinolinecarboxylic acid, 4-hydroxy-8-(trifluoromethoxy)-, ethyl ester MFCD00221480

密度	1.4±0.1 g/cm3
沸点	338.0±37.0 °C at 760 mmHg
熔点	235ºC
分子式	C₁₃H₁₀F₃NO₄
分子量	301.218
闪点	158.2±26.5 °C
精确质量	301.056183
PSA	68.39000
LogP	4.67
蒸汽压	0.0±0.8 mmHg at 25°C
折射率	1.557
储存条件	-20°C

Name:	Ethyl 4-oxo-8-(trifluoromethoxy)-1 4-dihydroquinoline-3-carboxylate Material Safety Data Sheet
Synonym:
CAS:	175278-35-0

Section 1 - Chemical Product MSDS Name:Ethyl 4-oxo-8-(trifluoromethoxy)-1 4-dihydroquinoline-3-carboxylate Material Safety Data Sheet
Synonym:

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS

CAS#	Chemical Name	content	EINECS#
175278-35-0	Ethyl 4-oxo-8-(trifluoromethoxy)-1,4-d	97%	unlisted

Hazard Symbols: XI
Risk Phrases: 36/37/38

Section 3 - HAZARDS IDENTIFICATION

EMERGENCY OVERVIEW
Irritating to eyes, respiratory system and skin.
Potential Health Effects
Eye:
Causes eye irritation.
Skin:
Causes skin irritation. May be harmful if absorbed through the skin.
Ingestion:
May cause irritation of the digestive tract. May be harmful if swallowed.
Inhalation:
Causes respiratory tract irritation. May be harmful if inhaled.
Chronic:
Not available.

Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Get medical aid. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:
Treat symptomatically and supportively.

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container.

Section 7 - HANDLING and STORAGE
Handling:
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Storage:
Store in a cool, dry place. Store in a tightly closed container.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 175278-35-0: Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Solid
Color: white
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 235 - 240 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C13H10F3NO4
Molecular Weight: 301.22

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Not available.
Conditions to Avoid:
Incompatible materials.
Incompatibilities with Other Materials:
Oxidizing agents, reducing agents, acids, bases.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide, fluorine, hydrogen fluoride gas.
Hazardous Polymerization: Has not been reported

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 175278-35-0 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
Ethyl 4-oxo-8-(trifluoromethoxy)-1,4-dihydroquinoline-3-carboxylate - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION

Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
No information available.
IMO
No information available.
RID/ADR
No information available.

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: XI
Risk Phrases:
R 36/37/38 Irritating to eyes, respiratory system
and skin.
Safety Phrases:
S 26 In case of contact with eyes, rinse immediately
with plenty of water and seek medical advice.
S 37/39 Wear suitable gloves and eye/face
protection.
WGK (Water Danger/Protection)
CAS# 175278-35-0: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 175278-35-0 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 175278-35-0 is not listed on the TSCA inventory.
It is for research and development use only.

SECTION 16 - ADDITIONAL INFORMATION
N/A

危害码 (欧洲)	Xi:Irritant;
风险声明 (欧洲)	36/37/38
安全声明 (欧洲)	26-36/37/39
海关编码	2933499090

海关编码	2933499090
中文概述	2933499090. 其他含喹琳或异喹啉环系的化合物〔但未进一步稠合的〕. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

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