188416-20-8

• 常用中文名：3-(6-氯-5-氟嘧啶-4-基)-2-(2,4-二氟苯基)-1-(1H-1,2,4-三唑-1-基)-2-丁醇盐酸盐
• 常用英文名：3-(6-CHLORO-5-FLUOROPYRIMIDIN-4-YL)-2,(2,4-DIFLUORO PHENYL)-1-(1H-1,2,4-TRIAZOLE-1-YL)BUTAN-2-OL HYDROCHLORIDE
• CAS号：188416-20-8
• 分子式：C₁₆H₁₄Cl₂F₃N₅O
• 分子量：420.216
• 发布时间：2018-12-31 19:27:44
• 更新时间：2024-01-06 12:34:07

名称

• 中文名: 3-(6-氯-5-氟嘧啶-4-基)-2-(2,4-二氟苯基)-1-(1H-1,2,4-三唑-1-基)-2-丁醇盐酸盐
• 英文名: 3-(6-chloro-5-fluoropyrimidin-4-yl)-2-(2,4-difluorophenyl)-1-(1,2,4-triazol-1-yl)butan-2-ol,hydrochloride
• 中文别名: 3-(6-氯-5-氟嘧啶-4-基)-2-(2,4-二氟苯基)-1-(1H-1,2,4-噻唑-1-基)-2-丁醇盐酸盐
• 英文别名: (2R,3S/2S,3R)-3-(4-chloro-5-fluoropyrimidin-6-yl)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol Hydrochloride; 6-Chloro-α-(2,4-difluorophenyl)-5-fluoro-β-methyl-α-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol, hydrochloride (1:1); 3-(6-Chloro-5-fluoropyrimidin-4-yl)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol hydrochloride; 4-Pyrimidineethanol, 6-chloro-α-(2,4-difluorophenyl)-5-fluoro-β-methyl-α-(1H-1,2,4-triazol-1-ylmethyl)-, hydrochloride (1:1); 3-(6-Chloro-5-fluoro-4-pyrimidinyl)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-2-butanol hydrochloride (1:1); 3-(6-Chloro-5-fluoropyrimidin-4-yl)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol hydrochloride (1:1); T6N CNJ DG EF FY1&XQR BF DF&1- AT5NN DNJ &&HCl; 3-(6-CHLORO-5-FLUOROPYRIMIDIN-4-YL)-2,(2,4-DIFLUORO PHENYL) - 1-(1H-1,2,4-TRIAZOLE-1-YL)BUTAN-2-OL HYDROCHLORIDE

物化性质

• 熔点: 126-130°C
• 分子式: C₁₆H₁₄Cl₂F₃N₅O
• 分子量: 420.216
• 精确质量: 419.052765
• PSA: 76.72000
• LogP: 3.63230
• 储存条件: 室温，干燥

安全

• 危害码 (欧洲): Xi
• 海关编码: 2933599090

合成路线

188416-28-6 86404-63-9 ~50% 188416-20-8

文献：DONGKOOK PHARMACEUTICAL CO., LTD.; KWON, Hyuk Chul; RHO, Man Dong; CHA, Kyung Hoi Patent: WO2011/96697 A2, 2011 ; Location in patent: Page/Page column 15-16 ;

188416-28-6 86404-63-9 ~49% 188416-20-8

文献：DONGKOOK PHARMACEUTICAL CO., LTD.; KWON, Hyuk Chul; RHO, Man Dong; CHA, Kyung Hoi Patent: WO2011/96697 A2, 2011 ; Location in patent: Page/Page column 15-16 ;

海关

海关编码	2933599090
中文概述	2933599090. 其他结构上有嘧啶环的化合物(包括其他结构上有哌嗪环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%