3916-18-5

• 常用中文名：DL-苏-3,4-二羟基苯丝氨酸
• 常用英文名：(2R,5R)-2,5-HEXANEDIOL
• CAS号：3916-18-5
• 分子式：C₉H₁₁NO₅
• 分子量：213.18700
• 相关类别： 生物化工 氨基酸及其衍生物 丝氨酸类衍生物
• 发布时间：2018-12-23 19:13:37
• 更新时间：2024-01-30 14:54:27

名称

• 中文名: DL-苏-3,4-二羟基苯丝氨酸
• 英文名: DL-threo-Droxidopa
• 中文别名: DL-苏-3,4-二羟基苯基丝氨酸; (2Rs,3rs)-2-氨基-3-(3,4-二羟基苯基)-3-羟基丙酸
• 英文别名: (2rs,3rs)-2-amino-3-(3,4-dihydroxy-phenyl)-3-hydroxy-propionic acid

物化性质

• 密度: 1.608g/cm3
• 沸点: 549.8ºC at 760mmHg
• 熔点: >200ºC
• 分子式: C₉H₁₁NO₅
• 分子量: 213.18700
• 闪点: 286.3ºC
• 精确质量: 213.06400
• PSA: 124.01000
• LogP: 0.24340
• 外观性状: powder | off-white to yellow-tan
• 折射率: 1.692
• 储存条件: -15°C
• 水溶解性: ethanol: 50 mg/mL Solutions should be freshly prepared.

MSDS

Name: DL-DOPS Material Safety Data Sheet Synonym: DL-threo-3,4-Dihydroxyphenylserine; DL-threo-3-(3,4-Dihydroxyphenyl)serine; beta, 3-Dihydroxy-DL-tyrosine threo-; DL-Tyrosine, beta, 3-dihydroxy-, threo CAS: 3916-18-5 Section 1 - Chemical Product MSDS Name:DL-DOPS Material Safety Data Sheet Synonym:DL-threo-3,4-Dihydroxyphenylserine; DL-threo-3-(3,4-Dihydroxyphenyl)serine; beta, 3-Dihydroxy-DL-tyrosine threo-; DL-Tyrosine, beta, 3-dihydroxy-, threo Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS CAS# Chemical Name content EINECS# 3916-18-5 DL-DOPS 100 223-480-5 Hazard Symbols: None Listed. Risk Phrases: None Listed. Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW The toxicological properties of this material have not been fully investigated. Potential Health Effects Eye: May cause eye irritation. Skin: May cause skin irritation. Ingestion: May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated. Inhalation: May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated. Chronic: No information found. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid immediately. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse. Ingestion: If victim is conscious and alert, give 2-4 cupfuls of milk or water. Never give anything by mouth to an unconscious person. Get medical aid immediately. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing Media: Use agent most appropriate to extinguish fire. Use water spray, dry chemical, carbon dioxide, or appropriate foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Clean up spills immediately, observing precautions in the Protective Equipment section. Sweep up or absorb material, then place into a suitable clean, dry, closed container for disposal. Avoid generating dusty conditions. Provide ventilation. Section 7 - HANDLING and STORAGE Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Storage: Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 3916-18-5: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: A respiratory protection program that meets OSHA's 29 CFR 1910.134 and ANSI Z88.2 requirements or European Standard EN 149 must be followed whenever workplace conditions warrant respirator use. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Solid Color: off-white Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: > 200 deg C Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: C9H11NO5 Molecular Weight: 213.19 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Stable. Conditions to Avoid: Incompatible materials, dust generation, strong oxidants. Incompatibilities with Other Materials: Strong oxidizing agents. Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide. Hazardous Polymerization: Will not occur. Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 3916-18-5: VT9626000 LD50/LC50: CAS# 3916-18-5: Oral, mouse: LD50 = >10 gm/kg. Carcinogenicity: DL-DOPS - Not listed by ACGIH, IARC, or NTP. Other: See actual entry in RTECS for complete information. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Not regulated as a hazardous material. IMO Not regulated as a hazardous material. RID/ADR Not regulated as a hazardous material. Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: Not available. Risk Phrases: Safety Phrases: S 24/25 Avoid contact with skin and eyes. S 28A After contact with skin, wash immediately with plenty of water. S 37 Wear suitable gloves. S 45 In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). WGK (Water Danger/Protection) CAS# 3916-18-5: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 3916-18-5 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 3916-18-5 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : VT9626000 CHEMICAL NAME : Serine, 3-(3,4-dihydroxyphenyl)-, DL-threo- CAS REGISTRY NUMBER : 3916-18-5 BEILSTEIN REFERENCE NO. : 2852792 LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C9-H11-N-O5 MOLECULAR WEIGHT : 213.21 WISWESSER LINE NOTATION : QVYZYQR CQ DQ HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >10 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JKXXAF Japanese Kokai Tokyo Koho Patents. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #81-104815 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 10 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JKXXAF Japanese Kokai Tokyo Koho Patents. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #81-104815

安全

• 安全声明 (欧洲): S24/25
• WGK德国: 2
• RTECS号: VT9626000