1522-46-9

• 常用中文名：2-异丙基乙酰乙酸乙酯
• 常用英文名：Ethyl 5-methyl-3-oxohexanoate
• CAS号：1522-46-9
• 分子式：C₉H₁₆O₃
• 分子量：172.221
• 发布时间：2018-02-23 08:00:00
• 更新时间：2024-01-02 18:57:29
• 下载msds

名称

• 中文名: 2-异丙基乙酰乙酸乙酯
• 英文名: Ethyl 2-isopropylacetoacetate
• 中文别名: 2-乙酰基-3-甲基丁酸乙酯; Α-異丙基乙醯乙酸乙酯; 2-异丙基乙本酰乙酸乙酯
• 英文别名: Ethyl 2-acetyl-3-methylbutanoate; Butanoic acid, 2-acetyl-3-methyl-, ethyl ester; ethyl 2-acetyl-3-methylbutyrate; ethyl 2-iso-propyl-3-oxo-butyrate; ethyl 3-methyl-2-acetylbutanoate; Ethyl2-isopropylacetoacetate; Ethyl α-isopropylacetoacetate; ethyl 2-isopropyl-3-oxobutanoate; ETHYL-ISO-PROPYLACETOACETATE; Hexanoic acid, 5-methyl-3-oxo-, ethyl ester; Ethyl 2-Isopropylacetoacetate; ETHYL A-ISOPROPYLACETOACETATE; 2-Isopropylacetoacetic acid ethyl ester; Acetoacetic acid, 2-isopropyl-, ethyl ester; Acetoacetic acid, 2-isopropyl-, ethyl ester (8CI); Ethyl 5-methyl-3-oxohexanoate; 2-Acetyl-3-methylbutyric Acid Ethyl Ester; Isovaleric acid,a-acetyl,ethyl ester; MFCD00042884; EINECS 216-192-6

物化性质

• 密度: 1.0±0.1 g/cm3
• 沸点: 207.1±8.0 °C at 760 mmHg
• 熔点: -20ºC
• 分子式: C₉H₁₆O₃
• 分子量: 172.221
• 闪点: 78.9±18.5 °C
• 精确质量: 172.109940
• PSA: 43.37000
• LogP: 1.94
• 外观性状: 透明无色液体
• 蒸汽压: 0.2±0.4 mmHg at 25°C
• 折射率: 1.423
• 储存条件: -20C

MSDS

Ethyl 2-Isopropylacetoacetate SAFETY DATA SHEET Section1. IDENTIFICATION Product name:Ethyl 2-Isopropylacetoacetate Section2. HAZARDS IDENTIFICATION GHS classification PHYSICAL HAZARDS Category 4 Flammable liquids HEALTH HAZARDSNot classified Not classified ENVIRONMENTAL HAZARDS GHS label elements, including precautionary statements None Pictograms or hazard symbols Signal wordWarning Combustible liquid Hazard statements Precautionary statements: Keep away from flames and hot surfaces. [Prevention] Wear protective gloves and eye/face protection. Store in a well-ventilated place. Keep cool. [Storage] [Disposal]Dispose of contents/container through a waste management company authorized by the local government. Section3. COMPOSITION/INFORMATION ON INGREDIENTS Substance/mixture:Substance Components:Ethyl 2-Isopropylacetoacetate >98.0%(GC) Percent: CAS Number:1522-46-9 2-Isopropylacetoacetic Acid Ethyl Ester , Ethyl 2-Acetyl-3-methylbutyrate , 2-Acetyl-3- Synonyms: methylbutyric Acid Ethyl Ester Chemical Formula:C9H16O3 Section4. FIRST AID MEASURES Inhalation:Remove victim to fresh air and keep at rest in a position comfortable for breathing. Get medical advice/attention if you feel unwell. Remove/Take off immediately all contaminated clothing. Rinse skin with Skin contact: water/shower. If skin irritation or rash occurs: Get medical advice/attention. Rinse cautiously with water for several minutes. Remove contact lenses, if present Eye contact: and easy to do. Continue rinsing. If eye irritation persists: Get medical advice/attention. Ingestion:Get medical advice/attention if you feel unwell. Rinse mouth. Protection of first-aiders:A rescuer should wear personal protective equipment, such as rubber gloves and air- tight goggles. Ethyl 2-Isopropylacetoacetate Section5. FIRE-FIGHTING MEASURES Suitable extinguishingDry chemical, foam, carbon dioxide. media: Unsuitable extinguishing Water (It may scatter and spread fire.) media: Precautions for firefighters: Fire-extinguishing work is done from the windward and the suitable fire-extinguishing method according to the surrounding situation is used. Uninvolved persons should evacuate to a safe place. In case of fire in the surroundings: Remove movable containers if safe to do so. Special protectiveWhen extinguishing fire, be sure to wear personal protective equipment. equipment for firefighters: Section6. ACCIDENTAL RELEASE MEASURES Use personal protective equipment. Keep people away from and upwind of spill/leak. Personal precautions, protective equipment and Ensure adequate ventilation. Entry to non-involved personnel should be controlled emergency procedures: around the leakage area by roping off, etc. Environmental precautions: Prevent product from entering drains. Methods and materials for Absorb spilled material in a suitable absorbent (e.g. rag, dry sand, earth, saw-dust). containment and cleaning In case of large amount of spillage, contain a spill by bunding. Adhered or collected up: material should be promptly disposed of, in accordance with appropriate laws and regulations. Prevention of secondary Remove all sources of ignition. Fire-extinguishing devices should be prepared in hazards:case of a fire. Use spark-proof tools and explosion-proof equipment. Section7. HANDLING AND STORAGE Precautions for safe handling Technical measures:Handling is performed in a well ventilated place. Wear suitable protective equipment. Prevent generation of vapour or mist. Keep away from flames and hot surfaces. Take measures to prevent the build up of electrostatic charge. Use explosion-proof equipment. Wash hands and face thoroughly after handling. Use a closed system, ventilation. Advice on safe handling: Avoid contact with skin, eyes and clothing. Conditions for safe storage, including any incompatibilities Storage conditions:Keep container tightly closed. Store in a cool, dark and well-ventilated place. Store away from incompatible materials such as oxidizing agents. Comply with laws. Packaging material: Section8. EXPOSURE CONTROLS / PERSONAL PROTECTION Engineering controls:Install a closed system or local exhaust as possible so that workers should not be exposed directly. Also install safety shower and eye bath. Personal protective equipment Respiratory protection: Vapor respirator. Follow local and national regulations. Hand protection:Protective gloves. Safety glasses. A face-shield, if the situation requires. Eye protection: Skin and body protection: Protective clothing. Protective boots, if the situation requires. Section9. PHYSICAL AND CHEMICAL PROPERTIES Physical state (20°C):Liquid Clear Form: Colour:Colorless - Almost colorless No data available Odour: pH: No data available Melting point/freezing point:No data available Boiling point/range:202°C Flash point:76°C Flammability or explosive limits: Ethyl 2-Isopropylacetoacetate Section9. PHYSICAL AND CHEMICAL PROPERTIES Lower:No data available Upper:No data available Relative density:0.96 Solubility(ies): [Water]No data available No data available [Other solvents] Section10. STABILITY AND REACTIVITY Chemical stability:Stable under proper conditions. Possibility of hazardous No special reactivity has been reported. reactions: Conditions to avoid:Open flame Incompatible materials: Oxidizing agents Hazardous decomposition Carbon monoxide, Carbon dioxide products: Section11. TOXICOLOGICAL INFORMATION Acute Toxicity:No data available Skin corrosion/irritation: No data available Serious eyeNo data available damage/irritation: Germ cell mutagenicity: No data available Carcinogenicity: IARC =No data available No data available NTP = Reproductive toxicity:No data available Section12. ECOLOGICAL INFORMATION Ecotoxicity: Fish:No data available Crustacea:No data available Algae:No data available Persistence / degradability: No data available BioaccumulativeNo data available potential(BCF): Mobility in soil Log Pow:No data available Soil adsorption (Koc):No data available Henry's LawNo data available constant(PaM3/mol): Section13. DISPOSAL CONSIDERATIONS Recycle to process, if possible. Consult your local regional authorities. You may be able to burn in a chemical incinerator equipped with an afterburner and scrubber system. Observe all federal, state and local regulations when disposing of the substance. Section14. TRANSPORT INFORMATION Hazards Class:Does not correspond to the classification standard of the United Nations UN-No:Not listed Section15. REGULATORY INFORMATION Safe management ordinance of dangerous chemical product (State Council announces on January 26, 2002 and revised on February 16,2011): Safe use and production, the storage of a dangerous chemical, transport, loading and unloading were prescribed. Ethyl 2-Isopropylacetoacetate SECTION 16 - ADDITIONAL INFORMATION N/A

安全

• 安全声明 (欧洲): 23-24/25
• WGK德国: 3
• 海关编码: 2918300090

合成路线

141-97-9 75-26-3 ~51% 1522-46-9

文献：Nambu, Mitch; White, James D. Chemical Communications, 1996 , # 14 p. 1619 - 1620

75-30-9 141-97-9 ~63% 1522-46-9

文献：Beddow, James E.; Davies, Stephen G.; Ling, Kenneth B.; Roberts, Paul M.; Russell, Angela J.; Smith, Andrew D.; Thomson, James E. Organic and Biomolecular Chemistry, 2007 , vol. 5, # 17 p. 2812 - 2825

141-97-9 67-63-0 ~% 1522-46-9

文献：Journal of the American Chemical Society, , vol. 62, p. 2392 Journal of the American Chemical Society, , vol. 65, p. 552 Organic Syntheses, , vol. Coll. Vol. III, p. 405,407

108-20-3 141-97-9 ~% 1522-46-9

文献：Journal of the American Chemical Society, , vol. 62, p. 2392 Journal of the American Chemical Society, , vol. 65, p. 552

108-21-4 141-97-9 ~% 1522-46-9

文献：Journal of the American Chemical Society, , vol. 62, p. 2612

75-30-9 66279-50-3 ~% 1522-46-9

文献：Tetrahedron, , vol. 27, p. 4777 - 4785

1007476-32-5 75-26-3 ~% 1522-46-9

文献：Helvetica Chimica Acta, , vol. 6, p. 1063

75-29-6 141-97-9 ~% 1540-21-2 1522-46-9

文献：Journal of Organic Chemistry, , vol. 34, p. 1969 - 1973

75-30-9 1007476-32-5 ~% 1522-46-9

文献：Justus Liebigs Annalen der Chemie, , vol. 145, p. 84

上下游产品

上游产品  9
141-97-9 75-26-3 75-30-9 67-63-0
108-20-3 108-21-4 66279-50-3 1007476-32-5
75-29-6
下游产品  10
565-61-7 5432-85-9 516-06-3 2217-17-6
29068-34-6 29068-33-5 89-81-6 589-43-5
108-64-5 123-51-3

海关

海关编码	2918300090
中文概述	2918300090 其他含醛基或酮基不含其他含氧基羧酸（包括酸酐、酰卤化物、过氧化物和过氧酸及该税号的衍生物）. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:30.0%
申报要素	品名, 成分含量, 用途
Summary	2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%