642-44-4

• 常用中文名：氨美啶
• 常用英文名：aminometradine
• CAS号：642-44-4
• 分子式：C₉H₁₃N₃O₂
• 分子量：195.21800
• 发布时间：2018-05-13 08:00:00
• 更新时间：2024-01-03 16:53:22

名称

• 中文名: 氨美啶
• 英文名: 6-amino-3-ethyl-1-prop-2-enylpyrimidine-2,4-dione
• 英文别名: Aminometramide; Catapyrin; 1-Allyl-6-amino-3-ethyl-2,4(1H,3H)-pyrimidinedione; Alacil; Aminometradinum [INN-Latin]; 1-allyl-3-ethyl-6-aminouracil; 6-amino-3-ethyl-1-(2-propenyl)-2,4(1H,3H)-pyrimidinedione; Mincard; 3-ethyl-1-allyl-6-amino-1H-pyrimidine-2,4-dione; Mictine; AMINOMETRADINE; 1-allyl-6-amino-3-ethyluracil; Allacyl; Katapyrin; 3-Aethyl-1-allyl-6-amino-1H-pyrimidin-2,4-dion

物化性质

• 密度: 1.167g/cm3
• 沸点: 292.8ºC at 760 mmHg
• 分子式: C₉H₁₃N₃O₂
• 分子量: 195.21800
• 闪点: 130.9ºC
• 精确质量: 195.10100
• PSA: 70.02000
• LogP: 0.37930
• 折射率: 1.534
• 储存条件: 库房通风低温干燥,与食品原料分开存放

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : YQ8665000 CHEMICAL NAME : Uracil, 1-allyl-6-amino-3-ethyl- CAS REGISTRY NUMBER : 642-44-4 BEILSTEIN REFERENCE NO. : 0175533 LAST UPDATED : 199612 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C9-H13-N3-O2 MOLECULAR WEIGHT : 195.25 WISWESSER LINE NOTATION : T6NVNVJ A2U1 C2 FZ HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 2300 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : FEPRA7 Federation Proceedings, Federation of American Societies for Experimental Biology. (Bethesda, MD) V.1-46, 1942-87. Volume(issue)/page/year: 14,392,1955 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 500 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : CLDND* Compilation of LD50 Values of New Drugs. (J.R. MacDougal, Dept. of National Health and Welfare, Food and Drug Divisions, 35 John St., Ottawa, Ont., Canada) TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 1300 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : PRPHA8 Produits Pharmaceutiques. (Paris, France) V.1-16, 1946-61. For publisher information, see PPRPAS. Volume(issue)/page/year: 13,125,1958 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 560 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : PRPHA8 Produits Pharmaceutiques. (Paris, France) V.1-16, 1946-61. For publisher information, see PPRPAS. Volume(issue)/page/year: 13,125,1958

合成路线

872828-38-1 ~% 642-44-4

文献：Papesch; Schroeder Journal of Organic Chemistry, 1951 , vol. 16, p. 1879,1881,1887

64-67-5 4852-21-5 ~% 642-44-4

文献：Papesch; Schroeder Journal of Organic Chemistry, 1951 , vol. 16, p. 1879,1881,1887

89607-21-6 372-09-8 ~% 642-44-4

文献：Papesch; Schroeder Journal of Organic Chemistry, 1951 , vol. 16, p. 1879,1881,1887

上下游产品

上游产品  5
872828-38-1 64-67-5 4852-21-5 89607-21-6
372-09-8
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