173676-59-0

• 常用中文名：4-氯-2-(三氟乙酰基)苯胺盐酸盐 水合物
• 常用英文名：4-Chloro-2-(trifluoroacetyl)aniline hydrochloride
• CAS号：173676-59-0
• 分子式：C₈H₆Cl₂F₃NO
• 分子量：260.040
• 发布时间：2018-12-29 18:30:29
• 更新时间：2026-07-02 18:56:24

名称

• 中文名: 4-氯-2-(三氟乙酰基)苯胺盐酸盐
• 英文名: 4-Chloro-2-(trifluoroacetyl)aniline hydrochloride
• 中文别名: 4-氯-2-(三氟乙酰基)苯胺盐酸盐水合物 中间体; 4-氯-2-(三氟乙酰基)苯胺盐酸盐依法韦仑中间体; 2-(三氟乙酰基)-4-氯苯胺盐酸盐; 抑制剂1-(2-Amino-5-chlorophenyl)-2,2,2-trifluoroethanone hydrochloride 1-（2-氨基-5-氯苯基）-2,2,2-三氟乙烷盐酸盐; 1-(2-氨基-5-氯苯基)-2,2,2-三氟乙酮盐酸盐; 4-氯-2-(三氟乙酰基)苯胺盐酸盐水合物(E-2); 抑制剂1-(2-Amino-5-chlorophenyl)-2,2,2-trifluoroethanone hydrochloride 1-(2-氨基-5-氯苯基)-2,2,2-三氟乙烷盐酸盐; 依非韦伦中间体E-2/4-氯-2-(三氟乙酰基)苯胺盐酸盐水合物; 艾法韦纶中间体E-2; 依法韦仑E-2; 依法韦仑中间体:三氟乙酮; 1-(2-氨基-5-氯苯基)-2,2,2-三氟乙烷-1-酮盐酸盐; 4-氯-2-(三氟乙酰基)苯胺盐酸盐E-2; 依法韦仑中间体E2; 2-(三氟乙酰基)-4-氯苯胺; 依非韦伦中间体E-2
• 英文别名: 1-(2-Amino-5-chlorophenyl)-2,2,2-trifluoroethanone hydrochloride; 4-CHLORO-2(1,1-DIHYDROXY-2,2,2-TRIFLUOROETHYL)ANILINE HCL (SD570); Ethanone, 1-(2-amino-5-chlorophenyl)-2,2,2-trifluoro-, hydrochloride (1:1); 1-(2-amino-5-chloro-phenyl)-2,2,2-trifluoro-ethane-1,1-diol; 4-Chloro-2-trifluoroacetylanilinehydrochloridehydrate; 2-(Trifluoroacetyl)-4-chloroaniline, Hydrochloride Hydrate (See C421880 for freebase); 4-Chloro-2-(Trifluoroacetyl)aniline Hydrochloride Hydrate (E-2); Ethanone, 1-(2-amino-5-chlorophenyl)-2,2,2-trifluoro-, hydrochloride; 4-Chloro-2-(Trifluoroacetyl)Aniline HCl; 4-Chloro-2-(trifluoroacetyl)aniline hydrochloride ISO 9001：2015 REACH; 4-Chloro-2-Trifluoracetyl Aniline Hydrochloride Hydrate; 4-CHLORO-2-(TRI FLUROACETYL)ANILINE HYDROCHLORIDE; 1-(2-Amino-5-chlorophenyl)-2,2,2-trifluoroethane-1,1-diolhydrochloride; 1-(2-Amino-5-chlorophenyl)-2,2,2-trifluoroethan-1-one hydrochloride; 2'-Amino-5'-chloro-2,2,2-trifluoroacetophenone hydrochloride; 1-(2-amino-5-chlorophenyl)-2,2,2-trifluoroethanone hydrochloride; 1-[5-chloro-2-(hydroxyaMino)phenyl]-2,2,2-trifluoroethan-1-one hydrochloride; Efavirenz Intermediate E-2; Efavirenz Intermediate: Trifluoroethanone; 1-(2-amino-5-chlorophenyl)-2,2,2-trifluoroethanone,hydrate,hydrochloride; 4-CHLORO-2,2,2-TRIFLUORO ACETYL ANILINE HYDROCHLORIDE; 4-Chloro-2-(trifluoroacetyl)aniline hydrochloride monohydrate; Ethanone,1-(2-amino-5-chlorophenyl)-2,2,2-trifluoro-, hydrochloride (1:1); 4-CHLORO-2(1,1-DIHYDROXY-2,2,2-TRIFLUOROETHYL)ANILINE HCL; 1-(2-Amino-5-chlorophenyl)-2,2,2-trifluoro-ethanone Hydrochloride Hydrate; 4-Chloro-2(1,1-Dihydroxy-2,2,2-Trifluoroethyl)Aniline HCL (S; ZR DG BVXFFF &&HCl; "4-Chloro-2-(1,1-dihydroxy-2,2,2-trifluoroethyl) aniline Hydrochloride"; 4-Chloro-2-(trifluoroacetyl)aniline, HCl hydrate; 1-(2-amino-5-chlorophenyl)-2,2,2-trifluoroethanone hydrate hydrochloride; 4-Chloro-2-trifluoro acetyaniline hydrochloride hydrate; 4-Chloro-2-trifluoroacetylanilineHCl(E2); 1-(2-Amino-5-chlorophenyl)-2,2,2-trifluoroethanone hydrochloride (1:1); 1-(2-Amino-5-chlorophenyl)-2,2,2-trifluoroethan-1-one hydrate hydrochloride

物化性质

• 沸点: 282.3ºC at 760 mmHg
• 熔点: 156-158ºC
• 分子式: C₈H₆Cl₂F₃NO
• 分子量: 260.040
• 闪点: 124.5ºC
• 精确质量: 258.977844
• PSA: 52.32000
• LogP: 3.98610
• 蒸汽压: 0.00339mmHg at 25°C
• 储存条件: 2~8℃

安全

• 危害码 (欧洲): Xi

合成路线

181190-33-0 ~% 173676-59-0

文献：WO2006/98969 A2, ; Page/Page column 35-37 ; WO 2006/098969 A2

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