18921-70-5

• 常用中文名：麦撒奎
• 常用英文名：L-Aspartic acid,N-[4-[[(2,4-diamino-5-methyl-6-quinazolinyl)methyl]amino]benzoyl]-
• CAS号：18921-70-5
• 分子式：C₂₁H₂₂N₆O₅
• 分子量：438.43700
• 发布时间：2018-09-23 15:40:58
• 更新时间：2023-01-16 18:12:19

名称

• 中文名: 麦撒奎
• 英文名: 2-[[4-[(2,4-diamino-5-methylquinazolin-6-yl)methylamino]benzoyl]amino]butanedioic acid
• 英文别名: Methasquin; N-{4-[(2,4-diamino-5-methyl-quinazolin-6-ylmethyl)-amino]-benzoyl}-aspartic acid; Aspartic acid,N-(p-(((2,4-diamino-5-methyl-6-quinazolinyl)methyl)amino)benzoyl)-,L; N-(p-(((2,4-Diamino-5-methyl-6-quinazolinyl)methyl)amino)benzoyl)-L-aspartic acid

物化性质

• 分子式: C₂₁H₂₂N₆O₅
• 分子量: 438.43700
• 精确质量: 438.16500
• PSA: 193.55000
• LogP: 2.99870

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : CI9320000 CHEMICAL NAME : Aspartic acid, N-(p-(((2,4-diamino-5-methyl-6-quinazolinyl)methyl)am ino)benzoyl)-, L- CAS REGISTRY NUMBER : 18921-70-5 LAST UPDATED : 199612 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C21-H22-N6-O5 MOLECULAR WEIGHT : 438.49 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 50110 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 158 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value MUTATION DATA TYPE OF TEST : Mutation test systems - not otherwise specified TEST SYSTEM : Human Lymphocyte DOSE/DURATION : 17 nmol/L REFERENCE : BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 25,1947,1976