50-11-3

• 常用中文名：美沙比妥
• 常用英文名：5,5-diethyl-1-methyl-1,3-diazinane-2,4,6-trione
• CAS号：50-11-3
• 分子式：C₉H₁₄N₂O₃
• 分子量：198.21900
• 发布时间：2018-09-23 12:54:54
• 更新时间：2024-01-06 11:28:03

名称

• 中文名: 美沙比妥
• 英文名: 5,5-diethyl-1-methyl-1,3-diazinane-2,4,6-trione
• 英文别名: 5,5-Diaethyl-1-methyl-2,4,6-trioxo-hexahydropyrimidin; Metabarbital; Gemonil; Endiemal; 5,5-diethyl-N-methyl-barbituric acid; metharbital; N-Methylbarbital; 5,5-Diethyl-1-methylbarbitursaeure; Methabarbital; Methylbarbital; 1-methyl-5,5-diethylbarbituric acid; Metharbitone; Metharbutal; Endiemalum

物化性质

• 密度: 1.122g/cm3
• 沸点: 302ºC at 760mmHg
• 分子式: C₉H₁₄N₂O₃
• 分子量: 198.21900
• 闪点: 136.4ºC
• 精确质量: 198.10000
• PSA: 66.48000
• LogP: 0.76770
• 折射率: 1.467

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : CQ3675000 CHEMICAL NAME : Barbituric acid, 5,5-diethyl-1-methyl- CAS REGISTRY NUMBER : 50-11-3 BEILSTEIN REFERENCE NO. : 0184688 LAST UPDATED : 199612 DATA ITEMS CITED : 3 MOLECULAR FORMULA : C9-H14-N2-O3 MOLECULAR WEIGHT : 198.25 WISWESSER LINE NOTATION : T6VMVNV FHJ D1 F2 F2 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 500 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 27ZIAQ "Drug Dosages in Laboratory Animals - A Handbook," Rev. ed., Barnes, C.D., and L.G. Eltherington, Berkeley, Univ. of California Press, 1973 Volume(issue)/page/year: -,-,1965 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 500 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : 27ZIAQ "Drug Dosages in Laboratory Animals - A Handbook," Rev. ed., Barnes, C.D., and L.G. Eltherington, Berkeley, Univ. of California Press, 1973 Volume(issue)/page/year: -,159,1973 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X7131 No. of Facilities: 9 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 339 (estimated) No. of Female Employees: 170 (estimated)

安全

• 危险品运输编码: UN 3249
• 包装等级: III
• 危险类别: 6.1(b)
• 海关编码: 2933540000

合成路线

77-25-8 598-50-5 ~65% 50-11-3

文献：Jenny, Christjohannes; Hesse, Manfred Helvetica Chimica Acta, 1981 , vol. 64, # 6 p. 1807 - 1811

129951-99-1 ~14% 50-11-3 129952-12-1 129952-09-6

文献：Aoyama, Hiromu; Hatori, Hiroaki Tetrahedron, 1990 , vol. 46, # 11 p. 3781 - 3788

67678-83-5 ~% 50-11-3

文献：Conrad; Zart Justus Liebigs Annalen der Chemie, 1905 , vol. 340, p. 339

67678-84-6 ~% 50-11-3

文献：Conrad; Zart Justus Liebigs Annalen der Chemie, 1905 , vol. 340, p. 339

1619-56-3 ~% 50-11-3

文献：Conrad; Zart Justus Liebigs Annalen der Chemie, 1905 , vol. 340, p. 339

57-44-3 74-88-4 ~% 50-11-3

文献：Halpern; Jones Journal of the American Pharmaceutical Association (1912-1977), 1949 , vol. 38, p. 352

7647-01-0 76072-09-8 ~% 50-11-3

文献：Majima Chemische Berichte, 1908 , vol. 41, p. 185

7647-01-0 67678-86-8 ~% 50-11-3 74-89-5

文献：Conrad; Zart Justus Liebigs Annalen der Chemie, 1905 , vol. 340, p. 339

上下游产品

上游产品  9
77-25-8 598-50-5 67678-83-5 67678-84-6
1619-56-3 57-44-3 74-88-4 7647-01-0
76072-09-8
下游产品  5
82845-38-3 10274-46-1 1114-38-1 714-59-0
62983-26-0

海关

海关编码	2933540000
中文概述	2933540000 其他丙二酰脲（巴比土酸）的衍生物以及它们的盐。监管条件:无。增值税率:17.0%。退税率:9.0%。最惠国关税:6.5%。普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933540000 other derivatives of malonylurea (barbituric acid); salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:20.0%