22348-44-3

• 常用中文名：反式-4-甲基氨基-环己醇
• 常用英文名：TRANS-4-(METHYLAMINO)CYCLOHEXANOL
• CAS号：22348-44-3
• 分子式：C₇H₁₅NO
• 分子量：129.200
• 发布时间：2018-06-08 09:33:52
• 更新时间：2024-01-30 12:40:28

名称

• 中文名: 顺-4-甲胺基环己醇
• 英文名: trans-4-(Methylamino)cyclohexanol
• 英文别名: TRANS-L-4-HYDROXY-PROLINE BENZYL ESTER HCL; L-4-Hydroxy-proline benzyl ester hydrochloride; trans-4-hydroxy-N-methylcyclohexylamine; trans-4-hydroxy-L-proline benzyl ester,hydrochloride; 4-(Methylamino)cyclohexanol; Cyclohexanol, 4-(methylamino)-; trans-4-Methylamino-cyclohexanol; trans-4-hydroxymethylcyclohexane carboxylic acid; trans-4-Hydroxy-L-prolin-benzylester,Hydrochlorid; phenylmethyl ester,hydrochloride

物化性质

• 密度: 1.0±0.1 g/cm3
• 沸点: 211.8±33.0 °C at 760 mmHg
• 分子式: C₇H₁₅NO
• 分子量: 129.200
• 闪点: 86.8±16.0 °C
• 精确质量: 129.115356
• PSA: 32.26000
• LogP: -0.08
• 蒸汽压: 0.0±0.9 mmHg at 25°C
• 折射率: 1.480
• 储存条件: 室温，干燥，密封

安全

• 危害码 (欧洲): Xi
• 海关编码: 2922199090

合成路线

111300-06-2 ~90% 22348-44-3

文献：ALMIRALL, S.A.; AIGUADE BOSCH, Jose; GUAL ROIG, Silvia; PRAT QUINONES, Maria; PUIG DURAN, Carlos Patent: WO2013/68552 A1, 2013 ; Location in patent: Page/Page column 39 ;

541-41-3 50910-54-8 ~% 22348-44-3

文献：CORTEX PHARMACEUTICALS, INC. Patent: WO2008/143963 A1, 2008 ; Location in patent: Example 51 ;

27489-63-0 ~80% 22348-44-3

文献：Dehmlow, Henrietta; Ackermann, Jean; Aebi, Johannes; Blum-Kaelin, Denise; Chucholowski, Alexander; Coassolo, Philippe; Hartman, Peter; Kansy, Manfred; Maerki, Hans Peter; Morand, Olivier; Von Der Mark, Elisabeth; Panday, Narendra; Ruf, Armin; Thoma, Ralf; Schulz-Gasch, Tanja Chimia, 2005 , vol. 59, # 3 p. 72 - 76

27489-62-9 ~% 22348-44-3

文献：Almirall, S.A.; Aiguade Bosch, Jose; Gual Roig, Silvia; Prat Quiñones, María; Puig Duran, Carlos Patent: EP2592077 A1, 2013 ;

50910-54-8 ~% 22348-44-3

文献：Venuti, Michael C.; Jones, Gordon H.; Alvarez, Robert; Bruno, John J. Journal of Medicinal Chemistry, 1987 , vol. 30, # 2 p. 303 - 318

22906-85-0 ~% 22348-44-3

文献：Russo,G.; Danieli,B. Gazzetta Chimica Italiana, 1965 , vol. 95, p. 438 - 447

579-58-8 ~% 22348-44-3

文献：CIBA Patent: US2152960 , 1936 ;

上下游产品

上游产品  6
111300-06-2 541-41-3 50910-54-8 27489-63-0
27489-62-9 579-58-8
下游产品  1
2976-84-3

海关

海关编码	2922199090
中文概述	2922199090. 其他氨基醇及其醚，酯和它们的盐（但含一种以上含氧基的除外）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
申报要素	品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装
Summary	2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%