641993-18-2

• 常用中文名：8-chloro-4-oxo-5-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxylic acid
• 常用英文名：8-chloro-4-oxo-5-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxylic acid
• CAS号：641993-18-2
• 分子式：C₁₁H₅ClF₃NO₃
• 分子量：291.611
• 发布时间：2017-03-01 10:16:13
• 更新时间：2024-01-12 11:13:21

名称

• 英文名: 8-chloro-4-oxo-5-(trifluoromethyl)-1H-quinoline-3-carboxylic acid
• 英文别名: 8-Chloro-4-oxo-5-(trifluoromethyl)-1,4-dihydro-3-quinolinecarboxylic acid; 8-chloro-4-oxo-5-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxylic acid; QC-4930; 3-Quinolinecarboxylic acid, 8-chloro-1,4-dihydro-4-oxo-5-(trifluoromethyl)-

物化性质

• 密度: 1.6±0.1 g/cm3
• 沸点: 391.4±42.0 °C at 760 mmHg
• 分子式: C₁₁H₅ClF₃NO₃
• 分子量: 291.611
• 闪点: 190.5±27.9 °C
• 精确质量: 290.990997
• PSA: 70.16000
• LogP: 4.21
• 蒸汽压: 0.0±0.9 mmHg at 25°C
• 折射率: 1.560

合成路线

1221573-17-6 ~% 641993-18-2

文献：VERTEX PHARMACEUTICALS INCORPORATED; ZHANG, Beili; KRAWIEC, Mariusz; LUISI, Brian; MEDEK, Ales Patent: WO2011/50220 A1, 2011 ; Location in patent: Page/Page column 44-45 ; WO 2011/050220 A1

121-50-6 ~% 641993-18-2

文献：VERTEX PHARMACEUTICALS INCORPORATED; ZHANG, Beili; KRAWIEC, Mariusz; LUISI, Brian; MEDEK, Ales Patent: WO2011/50220 A1, 2011 ; WO 2011/050220 A1

93514-81-9 ~% 641993-18-2

文献：VERTEX PHARMACEUTICALS INCORPORATED; ZHANG, Beili; KRAWIEC, Mariusz; LUISI, Brian; MEDEK, Ales Patent: WO2011/50220 A1, 2011 ; WO 2011/050220 A1

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