144690-33-5

• 常用中文名：4-(1-羟基-1-甲基乙基)-2-丙基-1-[4-[2-(三苯甲基四氮唑-5-基)苯基]苯基]甲基咪唑-5-羧酸乙酯
• 常用英文名：Ethyl 4-(2-hydroxypropan-2-yl)-2-propyl-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-imidazole-5-carboxylate
• CAS号：144690-33-5
• 分子式：C₄₅H₄₄N₆O₃
• 分子量：716.86900
• 发布时间：2017-05-03 17:37:57
• 更新时间：2026-07-11 16:01:42

名称

• 中文名: 4-(1-羟基-1-甲基乙基)-2-丙基-1-[4-[2-(三苯甲基四氮唑-5-基)苯基]苯基]甲基咪唑-5-羧酸乙酯
• 英文名: Ethyl 4-(2-hydroxy-2-propanyl)-2-propyl-1-{[2'-(1-trityl-1H-tetra zol-5-yl)-4-biphenylyl]methyl}-1H-imidazole-5-carboxylate
• 中文别名: 奥美沙坦乙酯三苯甲基杂质; 奥美沙坦酯杂质28; 4-(1-羟基-1-甲基乙基)-2-丙基-1-[[2'-[2-(三苯基甲基)-2H-四氮唑-5-基]联苯-4-基]甲基]咪唑-5-羧酸乙酯; 4-(2-羟基丙-2-基)-2-丙基-1-((2'-(1-三苯甲基-1H-四唑-5-基)-[1,1'-联苯]-4-基)甲基)-1H-咪唑-5-羧酸酯(奥美沙坦酯杂质); 奥美沙坦酯杂质31; 奥美沙坦酯杂质; 奥美沙坦乙酯三乙基杂质; 4-(2-羟基丙-2-基)-2-丙基-1-((2'-(1-三苯甲基-1H-四唑-5-基)-[1,1'-联苯]-4-基)甲基)-1H-咪唑-5-羧酸酯; 三苯甲基奥美沙坦乙酯; 奥美沙坦乙酯三甲基杂质; 奥美沙坦乙酯三苯酯杂质
• 英文别名: Ethyl 4-(2-hydroxy-2-propanyl)-2-propyl-1-{[2'-(1-trityl-1H-tetra zol-5-yl)-4-biphenylyl]methyl}-1H-imidazole-5-cboxylate; ethyl 4-(1-hydroxy-1-methylethyl)-2-propyl-1-[[2'-(N-triphenylmethyl-1H-tetrazole-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-carboxylate; 1H-imidazole-5-cboxylic acid, 2-propyl-4-(1-hydroxy-1-methylethyl)-1-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-,ethyl ester; ethyl 5-(1-hydroxy-1-methylethyl)-2-propyl-3-[2'-(1-trityl-1H-tetrazol-5-yl)biphenyl-4-ylmethyl]-3H-imidazole-4-carboxylate; Trityl olMestan ethyl ester; Azilstan medoxomil impurity229; OlMestan Ethyl Ester Trityl IMpurity; Olmestan Ethyl Ester Trityl Impurity 1H-Imidazole-5-cboxylic acid, 4-(1-hydroxy-1-methylethyl)-2- propyl-1-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1'- biphenyl]-4-yl]methyl]-, ethyl ester' Ethyl 4-(1-hydroxy-1- methylethyl)-2-propyl-1-[4-[2-(trityltetrazol-5; ethyl 4-(1-hydroxy-1-methylethyl)-2-propyl-1-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5yl]biphenyl-4-yl]methyl]imidazole-5-carboxylate; 4-(pyrrol-1-yl)benzoic acid ethyl ester; ethyl 4-(pyrrol-1-yl)benzoate; Ethyl 4-(2-hydroxypropan-2-yl)-2-propyl-1-(2(2-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)ethyl)-1H-imidazole-5-cboxylate; ethyl 4-pyrrolylbenzoate; OMSTINT-J; 5-(4'-(dibromomethyl)-[1,1'-biphenyl]-2-yl)-1H-tetrazole; Olmestan Medoxomil Impurity 28; 4-(1-Hydroxy-1-methylethyl)-2-propyl-1[4-[2-(trityltetrazol-5-yl)phenyl]phenyl]methylimidazo-5-cboxylate ethyl; 2-propyl-1-[[2'-[1-(triphenylMethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]Methyl]-, ethyl ester; Ethyl 4-(2-hydroxypropan-2-yl)-2-propyl-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-imidazole-5-cboxylate (Olmestan Medoxomi Impurity); ethyl 4-(1-hydroxy-1-methylethyl)-2-propyl-1-{4-[2-(trityltetrazol-5-yl)-phenyl]phenyl}-methylimidazole-5-carboxylate; Olmestan ester impurity 28; Ethyl 4-(2-hydroxypropan-2-yl)-2-propyl-1-((2'-(1-trityl-1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-1H-imidazole-5-cboxylate; 4-(1-hydroxy-1-methylethyl)-2-propyl-1-[[2'-[1-(triphenylmethyl)-1H-tetrazol; 1-(4-ethoxycarbonylphenyl)pyrrole; Ethyl 4-(2-hydroxypropan-2-yl)-2-propyl-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-imidazole-5-cboxylate; 4-(1-Hydroxy-1-methylethyl)-2-propyl-1-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-1H-imidazole-5-cboxylic acid ethyl ester; Olmestan Medoxomil Impurity 31; ethyl 4-(2-hydroxypropan-2-yl)-2-propyl-1-((2'-(1-trityl-1H-tetrazol-5-yl)biphenyl-4-yl)methyl)-1H-imidazole-5-carboxylate; Olmestan Medoxomil-19; 1H-Imidazole-5-cboxylic acid, 4-(1-hydroxy-1-methylethyl); 1H-IMidazole-5-cboxylic acid, 4-(1-hydroxy-1-Methylethyl)-2-propyl-1-[[2'-[1-(triphenylMethyl)-1H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]Methyl]-, ethyl ester; 1H-IMidazole-5-cboxylic acid, 4-(1-hydroxy-1-Methylethyl)-2-propyl-1-[[2'-[1; ethyl 4-(1H-pyrrol-1-yl)benzoate; Olmestan Medoxomil impurity 2/Olmestan Ethyl Ester Trityl Impurity/Ethyl 4-(2-Hydroxypropan-2-yl)-2-propyl-1-((2'-(1-trityl-1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-imidazole-5-cboxylate; ethyl-4-(1-hydroxymethylethyl)-2-propyl-1-{4-(2-trityltetrazol-5-yl)phenyl}phenylmethylimidazole-5-carboxylate; ethyl 4-(1-hydroxy-1-methylethyl)-2-propyl-1-{4-[2-(1-trityltetrazol-5-yl)phenyl]phenylmethyl}imidazole-5-carboxylate

物化性质

• 分子式: C₄₅H₄₄N₆O₃
• 分子量: 716.86900
• 精确质量: 716.34700
• PSA: 107.95000
• LogP: 8.44870
• 储存条件: 室温

合成路线

124750-51-2 144689-93-0 ~91% 144690-33-5

文献：KRKA Patent: WO2007/17135 A2, 2007 ; Location in patent: Page/Page column 5; 21 ;

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