81012-92-2

81012-92-2结构式

常用中文名：(2-萘氧基)醋酸N-羟基丁二酰亚胺酯
常用英文名：(2-naphthoxy)acetic acid n-hydroxysuccinimide ester
CAS号：81012-92-2
分子式：C₁₆H₁₃NO₅
分子量：299.27800
发布时间：2018-12-20 15:46:17
更新时间：2024-04-07 16:50:01

中文名	(2-萘氧基)醋酸N-羟基丁二酰亚胺酯
英文名	(2-naphthoxy)acetic acid n-hydroxysuccinimide ester
英文别名	2-Naphthoxyacetic acid succinimidyl ester [(2-Naphthalenyl)oxy]acetic acid 2,5-dioxopyrrolidin-1-yl ester N-[(2-Naphtyloxy)acetoxy]succinimide N-Hydroxysuccinimid-2-naphthoxy-essigsaeureester 2-(naphthalen-2-yloxy)acetic acid N-hydroxysuccinimide ester 2-NAPHTHOXYACETIC ACID N-HYDROXYSUCCINIMIDE ESTER CRYSTALLINE (2-naphthoxy)acetic acid MFCD00004065 succinimidyl 2-naphthoxyacetate (2-Naphthoxy)acetic acid N-hydroxysuccinimideester N-Succinimidyl 2-naphthoxyacetate succinimido (2-naphthyloxy)acetate (2-NAPHTHOXY)ACETIC ACID N-HYDROXYSUCC N-hydroxysuccinimide 2-(naphthalen-2-yloxy)acetic acid ester

密度	1.4g/cm3
沸点	485.1ºC at 760 mmHg
熔点	150-152ºC(lit.)
分子式	C₁₆H₁₃NO₅
分子量	299.27800
闪点	247.2ºC
精确质量	299.07900
PSA	72.91000
LogP	1.76370
折射率	1.649
储存条件	密闭于0-6 ºC阴凉干燥环境中
稳定性	遵照规定使用和储存则不会分解。
分子结构	1、摩尔折射率：77.76 2、摩尔体积（m³/mol）：213.4 3、等张比容（90.2K）：601.9 4、表面张力（dyne/cm）：63.3 5、极化率（10 ^-24cm ³）：30.82
计算化学	1.疏水参数计算参考值（XlogP）:2.2 2.氢键供体数量:0 3.氢键受体数量:5 4.可旋转化学键数量:5 5.互变异构体数量:3 6.拓扑分子极性表面积72.9 7.重原子数量:22 8.表面电荷:0 9.复杂度:448 10.同位素原子数量:0 11.确定原子立构中心数量:0 12.不确定原子立构中心数量:0 13.确定化学键立构中心数量:0 14.不确定化学键立构中心数量:0 15.共价键单元数量:1
更多	1. 性状：无可用 2. 密度（g/mL,25/4℃）：无可用 3. 相对蒸汽密度（g/mL,空气=1）：无可用 4. 熔点（ºC）：150-152 5. 沸点（ºC,常压）：无可用 6. 沸点（ºC,5.2kPa）：无可用 7. 折射率：无可用 8. 闪点（ºC）：无可用 9. 比旋光度（º）：无可用 10. 自燃点或引燃温度（ºC）：无可用 11. 蒸气压（kPa,25ºC）：无可用 12. 饱和蒸气压（kPa,60ºC）：无可用 13. 燃烧热（KJ/mol）：无可用 14. 临界温度（ºC）：无可用 15. 临界压力（KPa）：无可用 16. 油水（辛醇/水）分配系数的对数值：无可用 17. 爆炸上限（%,V/V）：无可用 18. 爆炸下限（%,V/V）：无可用 19. 溶解性：无可用

Name:	(2-Naphthoxy)Acetic Acid N-Hydroxysuccinimide Ester 98% Material Safety Data Sheet
Synonym:	None Known
CAS:	81012-92-2

Section 1 - Chemical Product MSDS Name:(2-Naphthoxy)Acetic Acid N-Hydroxysuccinimide Ester 98% Material Safety Data Sheet
Synonym:None Known

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS

CAS#	Chemical Name	content	EINECS#
81012-92-2	(2-Naphthoxy)Acetic Acid, N-Hydroxysuc	98	279-655-1

Hazard Symbols: None Listed.
Risk Phrases: None Listed.

Section 3 - HAZARDS IDENTIFICATION

EMERGENCY OVERVIEW
Moisture sensitive.The toxicological properties of this material have not been fully investigated.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation.
Ingestion:
May cause irritation of the digestive tract. The toxicological properties of this substance have not been fully investigated.
Inhalation:
May cause respiratory tract irritation. The toxicological properties of this substance have not been fully investigated.
Chronic:
No information found.

Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Notes to Physician:

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Runoff from fire control or dilution water may cause pollution.
Extinguishing Media:
In case of fire, use water, dry chemical, chemical foam, or alcohol-resistant foam. Use agent most appropriate to extinguish fire. Do NOT get water inside containers.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions.
Provide ventilation. Do not get water inside containers.

Section 7 - HANDLING and STORAGE
Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation. Do not allow contact with water. Keep from contact with moist air and steam.
Storage:
Store in a tightly closed container. Keep refrigerated. (Store below 4C/39F.) Store protected from moisture.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use process enclosure, local exhaust ventilation, or other engineering controls to control airborne levels.
Exposure Limits CAS# 81012-92-2: Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166.
Skin:
Wear appropriate protective gloves and clothing to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to minimize contact with skin.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Powder
Color: white to off-white
Odor: None reported.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 150.00 - 152.00 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C16H13NO5
Molecular Weight: 299.27

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable under normal temperatures and pressures. May decompose on exposure to moist air or water.
Conditions to Avoid:
Incompatible materials, dust generation, moisture, excess heat, strong oxidants.
Incompatibilities with Other Materials:
Moisture, oxidizing agents, strong acids.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, irritating and toxic fumes and gases, carbon dioxide, nitrogen.
Hazardous Polymerization: Has not been reported.

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 81012-92-2 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
(2-Naphthoxy)Acetic Acid, N-Hydroxysuccinimide Ester - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION

Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing Group:
IMO
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing Group:
RID/ADR
Shipping Name: Not regulated.
Hazard Class:
UN Number:
Packing group:

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 81012-92-2: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 81012-92-2 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 81012-92-2 is not listed on the TSCA inventory.
It is for research and development use only.

SECTION 16 - ADDITIONAL INFORMATION
N/A

生态学数据:

该物质对环境可能有危害，对水体应给予特别注意。

安全声明 (欧洲)	S24/25
海关编码	2925190090

120-23-0

81012-92-2

文献：Ferreira, Rafaela S.; Dessoy, Marco A.; Pauli, Ivani; Souza, Mariana L.; Krogh, Renata; Sales, Ana I. L.; Oliva, Glaucius; Dias, Luiz C.; Andricopulo, Adriano D. Journal of Medicinal Chemistry, 2014 , vol. 57, # 6 p. 2380 - 2392

上游产品 1
120-23-0
下游产品 0

海关编码	2925190090
中文概述	2925190090 其他酰亚胺及其衍生物盐. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:6.5% 普通关税:30.0%
申报要素	品名, 成分含量, 用途
Summary	2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

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