63127-20-8

• 常用中文名：4-(4-methylpiperazin-1-yl)-8-(trifluoromethyl)-10H-thieno[3,4-b][1,5]benzodiazepine
• 常用英文名：4-(4-methylpiperazin-1-yl)-8-(trifluoromethyl)-10H-thieno[3,4-b][1,5]benzodiazepine
• CAS号：63127-20-8
• 分子式：C₁₇H₁₇F₃N₄S
• 分子量：366.40400
• 发布时间：2017-01-30 07:15:24
• 更新时间：2024-01-13 23:45:35

名称

• 英文名: 4-(4-methylpiperazin-1-yl)-8-(trifluoromethyl)-10H-thieno[3,4-b][1,5]benzodiazepine
• 英文别名: 10-(4-Methyl-1-piperazinyl)-6-trifluoromethyl-4H-thieno(3,4-b)(1,5)benzodiazepine; 4H-Thieno(3,4-b)(1,5)benzodiazepine,10-(4-methyl-1-piperazinyl)-6-trifluoromethyl

物化性质

• 密度: 1.46g/cm3
• 沸点: 464.2ºC at 760 mmHg
• 分子式: C₁₇H₁₇F₃N₄S
• 分子量: 366.40400
• 闪点: 234.5ºC
• 精确质量: 366.11300
• PSA: 59.11000
• LogP: 3.59900
• 折射率: 1.658

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : XJ9008200 CHEMICAL NAME : 4H-Thieno(3,4-b)(1,5)benzodiazepine, 10-(4-methyl-1-piperazinyl)-6-trifluoromethyl- CAS REGISTRY NUMBER : 63127-20-8 LAST UPDATED : 199612 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C17-H17-F3-N4-S MOLECULAR WEIGHT : 366.44 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 600 mg/kg TOXIC EFFECTS : Nutritional and Gross Metabolic - body temperature decrease REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 23,884,1980