63127-20-8

63127-20-8 structure

63127-20-8 structure

Name: 4-(4-methylpiperazin-1-yl)-8-(trifluoromethyl)-10H-thieno[3,4-b][1,5]benzodiazepine
Chemical Name: 4-(4-methylpiperazin-1-yl)-8-(trifluoromethyl)-10H-thieno[3,4-b][1,5]benzodiazepine
CAS Number: 63127-20-8
Molecular Formula: C₁₇H₁₇F₃N₄S
Molecular Weight: 366.40400
Create Date: 2017-01-30 07:15:24
Modify Date: 2024-01-13 23:45:35

Name	4-(4-methylpiperazin-1-yl)-8-(trifluoromethyl)-10H-thieno[3,4-b][1,5]benzodiazepine
Synonyms	10-(4-Methyl-1-piperazinyl)-6-trifluoromethyl-4H-thieno(3,4-b)(1,5)benzodiazepine 4H-Thieno(3,4-b)(1,5)benzodiazepine,10-(4-methyl-1-piperazinyl)-6-trifluoromethyl

Density	1.46g/cm3
Boiling Point	464.2ºC at 760 mmHg
Molecular Formula	C₁₇H₁₇F₃N₄S
Molecular Weight	366.40400
Flash Point	234.5ºC
Exact Mass	366.11300
PSA	59.11000
LogP	3.59900
Index of Refraction	1.658

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XJ9008200

CHEMICAL NAME :: 4H-Thieno(3,4-b)(1,5)benzodiazepine, 10-(4-methyl-1-piperazinyl)-6-trifluoromethyl-

CAS REGISTRY NUMBER :: 63127-20-8

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C17-H17-F3-N4-S

MOLECULAR WEIGHT :: 366.44

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 600 mg/kg

TOXIC EFFECTS :: Nutritional and Gross Metabolic - body temperature decrease

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 23,884,1980