CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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XJ5075000
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CHEMICAL NAME :
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Thiazole, 2-hydrazino-4-(p-nitrophenyl)-
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CAS REGISTRY NUMBER :
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26049-70-7
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BEILSTEIN REFERENCE NO. :
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0230245
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LAST UPDATED :
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199612
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DATA ITEMS CITED :
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4
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MOLECULAR FORMULA :
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C9-H8-N4-O2-S
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MOLECULAR WEIGHT :
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236.27
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WISWESSER LINE NOTATION :
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T5N CSJ BMZ ER DNW
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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2700 mg/kg/46W-C
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TOXIC EFFECTS :
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Tumorigenic - Carcinogenic by RTECS criteria Gastrointestinal - tumors Skin and Appendages - tumors
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REFERENCE :
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JNCIAM Journal of the National Cancer Institute. (Washington, DC) V.1-60, 1940-78. For publisher information, see JJIND8. Volume(issue)/page/year: 51,403,1973
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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8000 mg/kg/46W-C
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TOXIC EFFECTS :
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Tumorigenic - equivocal tumorigenic agent by RTECS criteria Lungs, Thorax, or Respiration - tumors Blood - leukemia
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REFERENCE :
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CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 33,1593,1973
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TYPE OF TEST :
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TD - Toxic dose (other than lowest)
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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37 gm/kg/46W-C
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TOXIC EFFECTS :
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Tumorigenic - Carcinogenic by RTECS criteria Gastrointestinal - tumors Skin and Appendages - tumors
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REFERENCE :
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CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 30,897,1970
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TYPE OF TEST :
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TD - Toxic dose (other than lowest)
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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29 gm/kg/44W-C
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TOXIC EFFECTS :
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Tumorigenic - Carcinogenic by RTECS criteria Skin and Appendages - tumors
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REFERENCE :
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PAACA3 Proceedings of the American Association for Cancer Research. (Waverly Press, 428 E. Preston St., Baltimore, MD 21202) V.1- 1954- Volume(issue)/page/year: 10,15,1969
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