166247-63-8

• 常用中文名：7-Deaza-2'-deoxy-7-iodoadenosine
• 常用英文名：7-Deaza-2'-deoxy-7-iodoadenosine
• CAS号：166247-63-8
• 分子式：C₁₁H₁₃IN₄O₃
• 分子量：376.150
• 相关类别： 信号通路 细胞周期/DNA损伤 DNA/RNA合成
• 发布时间：2017-08-10 03:08:02
• 更新时间：2026-07-16 13:37:01
• Deaza-2'-deoxy-7-iodoadenosine 是包含 7-Deazaadenine 的修饰的寡核苷酸。

名称

• 中文名: 7-DEAZA-7-碘-2'-脱氧腺苷
• 英文名: 7-deaza-2'-deoxy-7-iodoadenosine
• 中文别名: 7-脱氮-2'-脱氧-7- IODOADENOSINE; 7-脱氮-7-碘-2'-脱氧腺苷; 5-碘-2'-脱氧结核菌素; 7-碘-7-脱氮-2'-脱氧腺苷; 7-脱氮-2'-脱氧-7-碘腺苷; 7-氮杂-2'-脱氧-7-碘腺嘌呤; 5-碘-2'-脱氧杀结核菌素; 7-I-7-DEAZA-2'-脱氧腺苷; (2R,3S,5R)-5-(4-氨基-5-碘-7H-吡咯并[2,3-D]嘧啶-7-基)-2-(羟甲基)四氢呋喃-3-醇
• 英文别名: 7-I-dA; 2'-deoxy-7-iodotubercidin; (2R,3S,5R)-5-(4-Amino-5-iodo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol; 4-amino-7-(2-deoxy-β-D-erythro-pentofuranosyl)-5-iodo-7H-pyrrolo[2,3-d]pyrimidine; 7-Iodo-7-deaza-2'-deoxyadenosine; 4-amino-7-(2'-deoxy-β-D-erythro-pentofuranosyl)-5-iodo-7H-pyrrolo[2,3-d]pyrimidine; 7-Deaza-7-lodo-2'-Deoxyadenosine; 7-Deaza-7-Iodo-2'-deoxyadeonsine; 2′-deoxy-7-iodo-7-deazaadenosine; 7-deaza-dA; 7-I-7-deaza-dATP; 7-DEAZA-7-IODO-2'-DEOXYADENOSINE //BP; 4-Amino-5-iodo-7-(2-deoxy-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidine; 7-I-7-Deaza-2'-dA; 7-(2-Deoxy-beta-D-erythro-pentofuranosyl)-5-iodo-7H-pyrrolo[2,3-d]pyrimidin-4-amine; 7-(2-Deoxy-β-D-erythro-pentofuranosyl)-5-iodo-7H-pyrrolo[2,3-d]pyrimidin-4-amine; (2R,3S,5R)-5-(4-amino-5-iodopyrrolo[2,3-d]pyrimidin-7-yl)-2-(hydroxymethyl)oxolan-3-ol; 2’-Deoxy-7-iodo tubercidin,7-Iodo-7-deaza-2’-deoxy adenosine; 7H-Pyrrolo[2,3-d]pyrimidin-4-amine, 7-(2-deoxy-b-D-erythro-pentofuranosyl)-5-iodo; 7-DEAZA-7-IODO-2'-DEOXYADENOSINE; 7-Deaza-7-I-2'-dA; 7-Deaza-2'-Deoxy-7-IodoAdenosine; 7-deaza-7-Iodo-deoxyadenosine; (2R,3S,5R)-5-(4-amino-5-iodo-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-(hydroxymethyl)tetrahydrofuran-3-ol; 2'-Deoxy-7-iodotubercidin; 7-Iodo-7-deaza-2’-deoxyadenosine, 4-Amino-7-(2-deoxy--D-ribofuranosyl)-5-iodo-7H-pyrrolo [2,3-d]pyrimidine; 7-I-7-Deaza-dA; 7H-Pyrrolo[2,3-d]pyrimidin-4-amine, 7-(2-deoxy-β-D-erythro-pentofuranosyl)-5-iodo; 5-Iodo-2'-deoxytubercidin

物化性质

• 密度: 2.4±0.1 g/cm3
• 沸点: 657.4±55.0 °C at 760 mmHg
• 分子式: C₁₁H₁₃IN₄O₃
• 分子量: 376.150
• 闪点: 351.4±31.5 °C
• 精确质量: 376.003235
• PSA: 106.42000
• LogP: 0.97
• 外观性状: 固体;White to Light yellow powder to crystal
• 蒸汽压: 0.0±2.1 mmHg at 25°C
• 折射率: 1.882
• 储存条件: 存放于惰性气体之中;避免空气

生物活性

• 描述: Deaza-2'-deoxy-7-iodoadenosine 是包含 7-Deazaadenine 的修饰的寡核苷酸。
• 相关类别:
  信号通路 >> 细胞周期/DNA损伤 >> DNA/RNA合成
  研究领域 >> 其他
• 参考文献:

  [1]. Frank Seela, et al. Oligonucleotides Containing 7‐Deazaadenines: The Influence of the 7‐Substituent Chain Length and Charge on the Duplex Stability. Research Article