126417-82-1

• 常用中文名：3-(4-氯苯基)-1-甲基-1H-吡唑-5-胺
• 常用英文名：3-(4-CHLOROPHENYL)-1-METHYL-1H-PYRAZOL-5-AMINE
• CAS号：126417-82-1
• 分子式：C₁₀H₁₀ClN₃
• 分子量：207.65900
• 发布时间：2018-12-18 17:14:27
• 更新时间：2024-01-09 10:04:10
• 下载msds

名称

• 中文名: 3-(4-氯苯基)-1-甲基-1H-吡唑-5-胺
• 英文名: 5-(4-chlorophenyl)-2-methylpyrazol-3-amine
• 英文别名: 5-Amino-3-(4-chlorophenyl)-1-methyl-1H-pyrazole; 1H-Pyrazol-5-amine,3-(4-chlorophenyl)-1-methyl; 3-(4-chlorophenyl)-1-methyl-1H-pyrazol-5-ylamine; 5-amino-3-(4-chlorophenyl)-1-methylpyrazole; 3-(4-Chlorophenyl)-1-Methyl-1H-Pyrazol-5-Amine; 5-(4-Chloro-phenyl)-2-methyl-2H-pyrazol-3-ylamine; 5-Amino-3-(p-chlorphenyl)-1-methyl-pyrazol

物化性质

• 密度: 1.32g/cm3
• 沸点: 394.4ºC at 760mmHg
• 熔点: 150ºC
• 分子式: C₁₀H₁₀ClN₃
• 分子量: 207.65900
• 闪点: 192.3ºC
• 精确质量: 207.05600
• PSA: 43.84000
• LogP: 2.90390
• 蒸汽压: 1.99E-06mmHg at 25°C
• 折射率: 1.643

MSDS

Name: 3-(4-Chlorophenyl)-1-methyl-1h-pyrazol-5-amine Material Safety Data Sheet Synonym: CAS: 126417-82-1 Section 1 - Chemical Product MSDS Name:3-(4-Chlorophenyl)-1-methyl-1h-pyrazol-5-amine Material Safety Data Sheet Synonym: Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS CAS# Chemical Name content EINECS# 126417-82-1 3-(4-Chlorophenyl)-1-methyl-1h-pyrazol 97+% unlisted Hazard Symbols: XI Risk Phrases: 36/37/38 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW Irritating to eyes, respiratory system and skin. Potential Health Effects Eye: Causes eye irritation. Skin: Causes skin irritation. May be harmful if absorbed through the skin. Ingestion: May cause irritation of the digestive tract. Causes gastrointestinal irritation with nausea, vomiting and diarrhea. May be harmful if swallowed. Inhalation: Causes respiratory tract irritation. May be harmful if inhaled. Chronic: Not available. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Get medical aid. Wash mouth out with water. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Treat symptomatically and supportively. Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Section 7 - HANDLING and STORAGE Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Storage: Store in a cool, dry place. Store in a tightly closed container. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 126417-82-1: Personal Protective Equipment Eyes: Not available. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Solid Color: Grey Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 170 - 172 deg C Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: C10H10CLN3 Molecular Weight: 207.66 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Stable. Conditions to Avoid: Incompatible materials. Incompatibilities with Other Materials: Strong oxidizing agents, acid chlorides. Hazardous Decomposition Products: Carbon monoxide, oxides of nitrogen, carbon dioxide. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 126417-82-1 unlisted. LD50/LC50: Not available. Carcinogenicity: 3-(4-Chlorophenyl)-1-methyl-1h-pyrazol-5-amine - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Not regulated as a hazardous material. IMO Not regulated as a hazardous material. RID/ADR Not regulated as a hazardous material. Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: XI Risk Phrases: R 36/37/38 Irritating to eyes, respiratory system and skin. Safety Phrases: S 22 Do not breathe dust. S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. WGK (Water Danger/Protection) CAS# 126417-82-1: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 126417-82-1 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 126417-82-1 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A

安全

• 危害码 (欧洲): Xi
• 风险声明 (欧洲): R36/37/38
• 安全声明 (欧洲): 26-36/37/39
• 海关编码: 2933199090

合成路线

4640-66-8 ~46% 126417-82-1

文献：SMITHKLINE BEECHAM CORPORATION Patent: WO2004/785 A2, 2003 ; Location in patent: Page 22 ; WO 2004/000785 A2

78583-86-5 60-34-4 ~27% 126417-82-1 120698-01-3

文献：Pharmazie, , vol. 44, # 8 p. 535 - 539

99-91-2 ~% 126417-82-1

文献：Pharmazie, , vol. 44, # 8 p. 535 - 539

78583-86-5 57-14-7 ~9% 126451-03-4 126417-82-1 详细

文献：Pharmazie, , vol. 44, # 8 p. 535 - 539

上下游产品

上游产品  5
4640-66-8 78583-86-5 60-34-4 99-91-2
57-14-7
下游产品  0

海关

海关编码	2933199090
中文概述	2933199090. 其他结构上有非稠合吡唑环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933199090. other compounds containing an unfused pyrazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%