1184-57-2

• 常用中文名：氢氧化甲基汞(II)
• 常用英文名：methylmercury(ii) hydroxide
• CAS号：1184-57-2
• 分子式：CH₄HgO
• 分子量：232.63200
• 发布时间：2018-09-06 14:05:22
• 更新时间：2024-01-11 17:30:30

名称

• 中文名: 甲基氢氧化汞(II)
• 英文名: methylmercury(ii) hydroxide
• 中文别名: 甲基氢氧化汞
• 英文别名: Methylmercury(II) hydroxide; MFCD00013924; methylmercury(1+),hydroxide; EINECS 214-667-2

物化性质

• 熔点: 137ºC
• 分子式: CH₄HgO
• 分子量: 232.63200
• 精确质量: 233.99700
• PSA: 20.23000
• LogP: 0.40450
• 外观性状: 固体片或粉末
• 储存条件:

  密封储存，储存于阴凉、干燥的库房。

• 稳定性:

  避免与水溶液，碱金属，碱土金属，许多有机无机的活性化学药品接触。

  与碱性金属，碱金属反应。

• 分子结构:

  1、摩尔折射率：无可用的

  2、摩尔体积（cm³/mol）：无可用的

  3、等张比容（90.2K）：无可用的

  4、表面张力（dyne/cm）：无可用的

  5、介电常数：无可用的

  6、极化率（10^-24cm³）：无可用的

  7、单一同位素质量：233.996815 Da

  8、标称质量：234 Da

  9、平均质量：232.6319 Da

• 计算化学:

  1.疏水参数计算参考值（XlogP）:无

  2.氢键供体数量:1

  3.氢键受体数量:1

  4.可旋转化学键数量:0

  5.互变异构体数量:无

  6.拓扑分子极性表面积1

  7.重原子数量:3

  8.表面电荷:0

  9.复杂度:2

  10.同位素原子数量:0

  11.确定原子立构中心数量:0

  12.不确定原子立构中心数量:0

  13.确定化学键立构中心数量:0

  14.不确定化学键立构中心数量:0

  15.共价键单元数量:2

• 更多:

  1. 性状：无色有特征气味的溶液

  2. 密度（g/mL,25℃）：未确定

  3. 相对蒸汽密度（g/mL,空气=1）：未确定

  4. 熔点（ºC）：未确定

  5. 沸点（ºC,常压）：未确定

  6. 沸点（ºC,12mmHg）：未确定

  7. 折射率(n20/D)：未确定

  8. 闪点（ºC）：未确定

  9. 比旋光度（º）：未确定

  10. 自燃点或引燃温度（ºC）：未确定

  11. 蒸气压（kPa,55ºC）：未确定

  12. 饱和蒸气压（kPa,25ºC）：未确定

  13. 燃烧热（KJ/mol）：未确定

  14. 临界温度（ºC）：未确定

  15. 临界压力（KPa）：未确定

  16. 油水（辛醇/水）分配系数的对数值：未确定

  17. 爆炸上限（%,V/V）：未确定

  18. 爆炸下限（%,V/V）：未确定

  19. 溶解性：与水完全可拌合的

MSDS

Section 1: Product Identification Chemical Name:Methylmercury (II) hydroxide,approx. 1M aqueous solution CAS Registry Number:1184-57-2 Formula:CH3HgOH EINECS Number:214-667-2 Chemical Family:organomercury compound Synonym:Methylmercury hydroxide Section 2: Composition and Information on Ingredients IngredientCAS NumberPercentACGIH (TWA)OSHA (PEL) Title Compound1184-57-223%0.01mg/m30.01mg/m3 water7732-18-577%no datano data Section 3: Hazards Identification Mercury salts are poisonous by ingestion and inhalation of dust. Possible risk of harm to the unborn child. Emergency Overview: Prolonged exposure may cause heritable genetic damage and impaired fertility. Primary Routes of Exposure:Ingestion, Skin. Eye Contact:May cause mild to severe irritation of the eyes. May deposit mercury in the lens of the eye. Skin Contact:May cause mild to severe irritation of the skin. Toxic in contact with skin. May be toxic by inhalation. May cause severe respiratory and gastrointestinal distress. May damage the Inhalation: central nervous system. Very toxic if swallowed. Lack of appetite, abdominal cramps, vomiting, kidney failure, paralysis. Mercury binds Ingestion: to thiol groups of protein. Poison. stomach upset and pain, mouth pain, vomiting, excessive salivation, urine products appear in the Acute Health Affects: blood. The chronic effects of mercury poisoning include stomatitis, tremors, psychic disturbances, excessive Chronic Health Affects: salivation, dermatitis, and pain on chewing. May cause heritable genetic damage and impair fertility. NTP:No IARC:Yes OSHA:No SECTION 4: First Aid Measures Immediately flush the eyes with copious amounts of water for at least 10-15 minutes. A victim may need Eye Exposure: assistance in keeping their eye lids open. Get immediate medical attention. Wash the affected area with water. Remove contaminated clothes if necessary. Seek medical assistance if Skin Exposure: irritation persists. Remove the victim to fresh air. Closely monitor the victim for signs of respiratory problems, such as difficulty Inhalation: in breathing, coughing, wheezing, or pain. In such cases seek immediate medical assistance. Seek medical attention immediately. Keep the victim calm. Give the victim water (only if conscious). Induce Ingestion: vomiting only if directed by medical personnel. SECTION 5: Fire Fighting Measures Flash Point:no data Autoignition Temperature:none Explosion Limits:none Extinguishing Medium:carbon dioxide, foam or dry powder If this product is involved in a fire, fire fighters should be equipped with a NIOSH approved positive pressure Special Fire Fighting Procedures: self- contained breathing apparatus and full protective clothing. Hazardous Combustion andIf involved in a fire this material may emit toxic fumes containing mercury. Decomposion Products: Unusual Fire or Explosion Hazards: No unusual fire or explosion hazards. SECTION 6: Accidental Release Measures Small spills can be mixed with vermiculite, sodium carbonate or other suitable non combustible adsorbent and Spill and Leak Procedures: swept up. SECTION 7: Handling and Storage Handling and Storage:Store in a cool, dry place in a tightly sealed container. SECTION 8: Exposure Controls and Personal Protection Eye Protection:Always wear approved safety glasses when handling a chemical substance in the laboratory. Skin Protection:Wear protective clothing and gloves. Ventilation:If possible, handle the material in an efficient fume hood. If ventilation is not available a respirator should be worn. The use of respirators requires a Respirator Respirator: Protection Program to be in compliance with 29 CFR 1910.134. Ventilation:If possible, handle the material in an efficient fume hood. Additional Protection:No additional protection required. SECTION 9: Physical and Chemical Properties Color and Form:colorless liq. Molecular Weight:232.63 Melting Point:no data Boiling Point:no data Vapor Pressure:no data Specific Gravity:no data Odor:none Solubility in Water:material is a water solution SECTION 10: Stability and Reactivity Stability:air and moisture stable Hazardous Polymerization:no hazardous polymerization Conditions to Avoid:none Incompatibility:azides, fulminates, active metals, reducing agents, and strong oxidizing agents. Decomposition Products:carbon monoxide, carbon dioxide, mercury fumes, and organic fumes. SECTION 11: Toxicological Information Oral (rat); LD50: 43300 ug/kg. Intraperitoneal (mouse); LD50: 20 mg/kg. Oral (monkey); LD: >3 mg/kg. Oral (rat); TDLo: 315 mg/kg/30W-C. Subcutaneous (rat); TDLo: 70 mg/kg/7D-I. Oral (monkey); TDLo: 26320 RTECS Data:mg/kg/43W-I. Oral (rat); TDLo: 50 mg/kg. Subcutaneous (rat); TDLo:100 mg/kg. Human HeLa cell; DNA inhibition: 10 umol/L. Human HeLa cell; Mutation test not-not otherwise specified: 7500 nmol/L. Intraperitoneal (mouse); DNA inhibition: 1 mg/kg. Carcinogenic Effects:No data Mutagenic Effects:Mutagen Tetratogenic Effects:Reproductive effector SECTION 12: Ecological Information Avoid release to groundwater or waterways. Very toxic to aquatic organisms. May cause long-term adverse Ecological Information: effects. SECTION 13: Disposal Considerations Disposal:Dispose of according to local, state and federal regulations. SECTION 14: Transportation Shipping Name (CFR):Mercury compounds, liquid, N.O.S. Hazard Class (CFR):6.1 Additional Hazard Class (CFR):NA Packaging Group (CFR):II UN ID Number (CFR):UN# 2024 Shipping Name (IATA):Mercury compound, liquid, N.O.S. Hazard Class (IATA):6.1 Additional Hazard Class (IATA):NA Packaging Group (IATA):II UN ID Number (IATA):UN# 2024 SECTION 15: Regulatory Information TSCA:Not listed in the TSCA inventory. SARA (Title 313):Title compound: See category N458 for reporting. Second Ingredient:None SECTION 16 - ADDITIONAL INFORMATION N/A

毒性和生态

生态学数据: 对水是极其危害的，即使是小量，对水体中的鱼和浮游生物是有毒害的。 对水中的有机物，鱼类有剧毒， 禁止进入水体。 若无政府许可，勿将材料排入周围环境。 CHEMICAL IDENTIFICATION RTECS NUMBER : OW4900000 CHEMICAL NAME : Mercury, hydroxymethyl- CAS REGISTRY NUMBER : 1184-57-2 LAST UPDATED : 199712 DATA ITEMS CITED : 60 MOLECULAR FORMULA : C-H4-Hg-O MOLECULAR WEIGHT : 232.64 WISWESSER LINE NOTATION : Q-HG-1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 43300 ug/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 20 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD - Lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Primate - monkey DOSE/DURATION : >3 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 105 mg/kg/15W-I TOXIC EFFECTS : Behavioral - muscle weakness Behavioral - alteration of operant conditioning Nutritional and Gross Metabolic - weight loss or decreased weight gain TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 315 mg/kg/30W-C TOXIC EFFECTS : Kidney, Ureter, Bladder - interstitial nephritis Biochemical - Metabolism (Intermediary) - porphyrin including bile pigments Related to Chronic Data - death TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 70 mg/kg/7D-I TOXIC EFFECTS : Peripheral Nerve and Sensation - structural change in nerve or sheath Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Nutritional and Gross Metabolic - weight loss or decreased weight gain TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Primate - monkey DOSE/DURATION : 26320 mg/kg/43W-I TOXIC EFFECTS : Brain and Coverings - other degenerative changes TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Primate - monkey DOSE/DURATION : 32 mg/kg/1.5Y-I TOXIC EFFECTS : Brain and Coverings - other degenerative changes TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Mammal - cat DOSE/DURATION : 19948 ug/kg/20D-I TOXIC EFFECTS : Brain and Coverings - other degenerative changes Behavioral - convulsions or effect on seizure threshold Related to Chronic Data - death TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral DOSE : 48 mg/kg SEX/DURATION : female 16-22 day(s) after conception lactating female 17 day(s) post-birth TOXIC EFFECTS : Reproductive - Effects on Embryo or Fetus - cytological changes (including somatic cell genetic material) Reproductive - Specific Developmental Abnormalities - Central Nervous System TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral DOSE : 50 mg/kg SEX/DURATION : female 1-20 day(s) after conception TOXIC EFFECTS : Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - hepatobiliary system Reproductive - Specific Developmental Abnormalities - urogenital system TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral DOSE : 50 mg/kg SEX/DURATION : female 1-20 day(s) after conception TOXIC EFFECTS : Reproductive - Effects on Embryo or Fetus - cytological changes (including somatic cell genetic material) TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral DOSE : 43 mg/kg SEX/DURATION : female 28 day(s) pre-mating female 1-19 day(s) after conception TOXIC EFFECTS : Reproductive - Effects on Embryo or Fetus - other effects to embryo TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral DOSE : 23500 ug/kg SEX/DURATION : female 28 day(s) pre-mating female 1-19 day(s) after conception TOXIC EFFECTS : Reproductive - Effects on Newborn - biochemical and metabolic TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous DOSE : 100 mg/kg SEX/DURATION : female 1-20 day(s) after conception TOXIC EFFECTS : Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - hepatobiliary system Reproductive - Specific Developmental Abnormalities - urogenital system TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous DOSE : 100 mg/kg SEX/DURATION : female 1-20 day(s) after conception TOXIC EFFECTS : Reproductive - Effects on Embryo or Fetus - cytological changes (including somatic cell genetic material) TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous DOSE : 7 mg/kg SEX/DURATION : female 8-21 day(s) after conception TOXIC EFFECTS : Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral DOSE : 3237 ug/kg SEX/DURATION : female 8 day(s) after conception TOXIC EFFECTS : Reproductive - Effects on Newborn - live birth index (measured after birth) Reproductive - Effects on Newborn - growth statistics (e.g.%, reduced weight gain) Reproductive - Effects on Newborn - behavioral TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intraperitoneal DOSE : 8 mg/kg SEX/DURATION : female 10 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue) TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous DOSE : 6 mg/kg SEX/DURATION : female 10 day(s) after conception TOXIC EFFECTS : Reproductive - Effects on Newborn - behavioral TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous DOSE : 24 mg/kg SEX/DURATION : female 7-12 day(s) after conception TOXIC EFFECTS : Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus) Reproductive - Specific Developmental Abnormalities - Central Nervous System TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous DOSE : 8 mg/kg SEX/DURATION : female 10 day(s) after conception TOXIC EFFECTS : Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue) TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous DOSE : 12 mg/kg SEX/DURATION : female 10 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Intravenous DOSE : 8 mg/kg SEX/DURATION : female 10 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Specific Developmental Abnormalities - craniofacial (including nose and tongue) TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral DOSE : 11550 ug/kg SEX/DURATION : female 1-24 week(s) after conception TOXIC EFFECTS : Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea) Reproductive - Effects on Embryo or Fetus - fetal death TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral DOSE : 88 mg/kg SEX/DURATION : female 30 day(s) pre-mating female 1-68 day(s) after conception TOXIC EFFECTS : Reproductive - Specific Developmental Abnormalities - Central Nervous System TYPE OF TEST : Specific locus test TYPE OF TEST : Sex chromosome loss and nondisjunction TYPE OF TEST : Cytogenetic analysis TYPE OF TEST : DNA inhibition TYPE OF TEST : Unscheduled DNA synthesis TYPE OF TEST : Dominant lethal test MUTATION DATA TEST SYSTEM : Rodent - mouse REFERENCE : MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 30,365,1975 *** REVIEWS *** ACGIH TLV-TWA 0.01 mg(Hg)/m3; STEL 0.03 mg/m3 DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 TOXICOLOGY REVIEW TJADAB Teratology, The International Journal of Abnormal Development. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.1- 1968- Volume(issue)/page/year: 12,311,1975 TOXICOLOGY REVIEW RREVAH Residue Reviews. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1962- Volume(issue)/page/year: 42,103,1972 *** U.S. STANDARDS AND REGULATIONS *** MSHA STANDARD-air:TWA 0.001 ppm (0.01 mg(Hg)/m3) DTLWS* "Documentation of the Threshold Limit Values for Substances in Workroom Air," Supplements. For publisher information, see 85INA8. Volume(issue)/page/year: 3,22,1973 OSHA PEL (Gen Indu):8H TWA 0.01 mg(Hg)/m3 CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1910.1000,1994 OSHA PEL (Construc):8H TWA 0.01 mg(Hg)/m3 (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1926.55,1994 OSHA PEL (Shipyard):8H TWA 0.01 mg(Hg)/m3 (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 29,1915.1000,1993 OSHA PEL (Fed Cont):8H TWA 0.01 mg(Hg)/m3 (skin) CFRGBR Code of Federal Regulations. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) Volume(issue)/page/year: 41,50-204.50,1994 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 0.01 mg(Hg)/m3;STEL 0.03 mg(Hg)/m3;Skin JAN 1993 OEL-BELGIUM:TWA 0.01 mg(Hg)/m3;STEL 0.03 mg(Hg)/m3;Skin JAN 1993 OEL-DENMARK:TWA 0.01 mg(Hg)/m3;Skin JAN 1993 OEL-FINLAND:TWA 0.01 mg(Hg)/m3;Skin JAN 1993 OEL-FRANCE:TWA 0.01 mg(Hg)/m3;Skin JAN 1993 OEL-THE NETHERLANDS:TWA 0.01 mg(Hg)/m3;STEL 0.02 mg(Hg)/m3;Skin JAN 1993 OEL-THE PHILIPPINES:TWA 0.01 mg(Hg)/m3 JAN 1993 OEL-SWEDEN:TWA 0.01 mg(Hg)/m3;Skin JAN 1993 OEL-THAILAND:TWA 0.01 mg(Hg)/m3;STEL 0.04 mg(Hg)/m3 JAN 1993 OEL-TURKEY:TWA 0.01 mg(Hg)/m3;Skin JAN 1993 OEL-UNITED KINGDOM:TWA 0.01 mg(Hg)/m3;STEL 0.03 mg(Hg)/m3;Skin JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO MERCURY, ORGANO-air:TWA 0.01 mg/m3;STEL 0.03 mg/m3 (Sk) REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992

安全

• 风险声明 (欧洲): R26/27/28
• 安全声明 (欧洲): S13;S28;S45
• 危险品运输编码: UN 2024
• 危险类别: 6.1
• 海关编码: 2931900090

合成路线

22967-92-6 ~% 1184-57-2

文献：Canadian Journal of Chemistry, , vol. 65, p. 491 - 496

3352-57-6 593-74-8 ~% 1184-57-2

文献：Journal of Physical Chemistry, , vol. 87, # 24 p. 4978 - 4981

143-36-2 20667-12-3 ~% 1184-57-2

文献：Canadian Journal of Chemistry, , vol. 61, p. 1428 - 1434

上下游产品

上游产品  5
22967-92-6 3352-57-6 593-74-8 143-36-2
20667-12-3
下游产品  0

海关

海关编码	2931900090
中文概述	2931900090. 其他有机-无机化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:AB(入境货物通关单,出境货物通关单). 最惠国关税:6.5%. 普通关税:30.0%
Summary	2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%