1070-42-4

• 常用中文名：bis(2-chloroethyl)phosphite
• 常用英文名：bis(2-chloroethyl)phosphite
• CAS号：1070-42-4
• 分子式：C₄H₉Cl₂O₃P
• 分子量：206.99200
• 发布时间：2017-05-23 00:03:06
• 更新时间：2024-01-09 12:39:41

名称

• 英文名: bis(2-chloroethyl)phosphite
• 英文别名: Phosphorous acid,bis(2-chloroethyl) ester; bis(2-chloroethyl) H-phosphonate; Einecs 213-975-4; Phosphonic acid,bis(2-chloroethyl) ester; bis(2-chloethyl) hydrogen phosphite; Ethanol,2-chloro-,phosphite (2:1); di(2-chloroethyl)phosphorous acid; 2-chloro-ethanophosphite(2:1); bis(2-chloroethyl) phosphonate

物化性质

• 沸点: 311.5ºC at 760mmHg
• 分子式: C₄H₉Cl₂O₃P
• 分子量: 206.99200
• 闪点: 142.2ºC
• 精确质量: 205.96700
• PSA: 52.28000
• LogP: 1.71640
• 蒸汽压: 0.012mmHg at 25°C
• 储存条件:

  库房通风低温干燥; 与食品原料分开存放

• 稳定性:

  可燃; 燃烧产生有毒磷氧化物,氯化物烟雾

• 计算化学:

  1.疏水参数计算参考值（XlogP）:0.7

  2.氢键供体数量:1

  3.氢键受体数量:3

  4.可旋转化学键数量:6

  5.互变异构体数量:2

  6.拓扑分子极性表面积38.7

  7.重原子数量:10

  8.表面电荷:0

  9.复杂度:67.5

  10.同位素原子数量:0

  11.确定原子立构中心数量:0

  12.不确定原子立构中心数量:0

  13.确定化学键立构中心数量:0

  14.不确定化学键立构中心数量:0

  15.共价键单元数量:1

毒性和生态

毒理学数据: 口服-大鼠 LD50: 260 毫克/公斤; 腹腔-小鼠 LDL0: 250 毫克/公斤 CHEMICAL IDENTIFICATION RTECS NUMBER : KK2800000 CAS REGISTRY NUMBER : 1070-42-4 BEILSTEIN REFERENCE NO. : 1705711 LAST UPDATED : 199612 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C4-H9-Cl2-O3-P MOLECULAR WEIGHT : 207.00 WISWESSER LINE NOTATION : G2OPO&O2G HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 260 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 30,470,1969 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 250 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : CBCCT* "Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. (National Academy of Science Library, 2101 Constitution Ave., NW, Washington, DC 20418) Volume(issue)/page/year: 7,790,1955 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Administration onto the skin SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 141 uL/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 30,470,1969 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84167 No. of Facilities: 21 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 21 (estimated)

合成路线

107-07-3 ~10% 1070-42-4

文献：Santschi, Nico; Togni, Antonio Journal of Organic Chemistry, 2011 , vol. 76, # 10 p. 4189 - 4193

140-08-9 ~% 1070-42-4

文献：Walsh Journal of the American Chemical Society, 1959 , vol. 81, p. 3023,3024

762-04-9 107-07-3 ~% 1070-42-4

文献：Fields Journal of the American Chemical Society, 1952 , vol. 74, p. 1528,1530

13598-36-2 107-07-3 ~% 1070-42-4

文献：Fisher, Henry C.; Prost, Lucie; Montchamp, Jean-Luc European Journal of Organic Chemistry, 2013 , # 35 p. 7973 - 7978

107-06-2 ~% 1070-42-4

文献：Bliznyuk,N.K. et al. J. Gen. Chem. USSR (Engl. Transl.), 1967 , vol. 37, # 4 p. 884 - 888,834 - 837

37984-64-8 762-04-9 ~% 1070-42-4

文献：Nuretdinova,O.N. Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1974 , vol. 23, p. 1365 Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1974 , vol. 23, p. 1438 - 1439

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