7084-24-4

• 常用中文名：氯化失车菊素-3-O-葡萄糖苷
• 常用英文名：Cyanidin-3-O-glucoside chloride
• CAS号：7084-24-4
• 分子式：C₂₁H₂₁ClO₁₁
• 分子量：484.838
• 相关类别： 生物化工 植物提取物
• 发布时间：2018-06-02 08:00:00
• 更新时间：2026-06-30 16:47:38
• 矢车菊素-3-O-葡萄糖苷 (Kuromanin chloride) 来源于桑叶,具有提高血糖浓度、维持脂质代谢平衡以降低肥胖的作用。
• 现代药理学研究证明矢车菊素-3-O-葡萄糖苷具有显著的抗氧化、抗肿瘤、保护神经系统、恢复短暂性视力减弱等多种医疗保健作用。另有研究发现矢车菊素-3-O-葡萄糖苷可作为植物保护剂，保护棉花叶片免受棉铃虫的危害。
  黑豆皮中矢车菊素-3-O-葡萄糖苷能够减少3T3-L1脂肪细胞胞内的活性氧物质的产生，从而剂量依赖地改善H2O2或者TNF-α诱导的胰岛素耐受性；同时能够减少视黄醇结合蛋白在Ⅱ型糖尿病大鼠的表达，改善高血糖症和提高胰岛素敏感度，从而改善糖尿病症状。

名称

• 中文名: 矢车菊素-3-O-葡萄糖苷
• 英文名: cyanidin 3-O-β-D-glucoside
• 中文别名: 花青素; 花青素对照品,HPLC(面积归一化法); 氰胺3-O-葡糖苷氯化物(氯库洛明); 矢车菊素-3-O-葡萄糖苷(对照品); 矢车菊素-3-O-葡萄糖苷氯化物, 来源于黑豆皮; 6-脱水-Β-D-葡萄糖; 矢车菊苷; 2-(3,4-二羟基苯基)-3-(β-D-吡喃葡萄糖氧基)-5,7-二羟基-1-苯并氯化物; 2-(3,4-二羟基苯基)-3-(BETA-D-吡喃葡萄糖氧基)-5,7-二羟基-1-苯并吡喃氯化物; 矢车菊素-3-O-葡萄糖苷,10 MM DMSO 溶液; 矢车菊素-3-0-葡糖糖苷; Cyanidin-3-O-glucoside chloride :矢车菊素; 矢车菊苷(-20°C); 氰胺3-葡糖苷; 矢车菊素-葡萄糖苷; 矢车菊素-3-O-葡萄糖苷(花青素)对照品; 氯化矢车菊素3-O-葡萄糖苷; 矢车菊素-3-O-葡; RAPGEF1 多克隆抗体-E-AB-19964; 2-(3,4-二羟基苯基)-3-(BETA-D-吡喃葡萄糖氧基)-5,7-二羟基-1-苯并吡喃鎓氯化物; 花青素对照品,HPLC(标定); 映山红提取物; 矢车菊色素-3-O-葡萄糖苷; 2-(3,4-二羟基苯基)-3-(Β-D-吡喃葡萄糖氧基)-5,7-二羟基-1-苯并吡喃氯化物; 罗恩 矢车菊素-3-O-葡萄糖苷 R001283; 矢车菊素-3-O-葡萄糖苷(花青素(C3G)); 2-(3,4-二羟基苯基)-3-(beta-D-吡喃葡萄糖氧基)-5,7-二羟基-1-苯并吡喃鎓氯化物; 2-(3,4-二羟基苯基)-5,7-二羟基-3-(((2S,3R,4S,5S,6R)-3,4,5-三羟基-6-(羟甲基)四氢-2H-吡喃-2-基)氧基)苯并吡喃氯化物; 7-二羟基-1-苯并吡喃鎓氯化物; 矢车菊素-3-O-葡萄糖苷, 分析对照品; 氯化矢车菊素-3-葡萄糖苷; 矢车菊苷/2-(3,4-二羟基苯基)-3-(Β-D-吡喃葡萄糖氧基)-5,7-二羟基-1-苯并氯化物; 矢车菊素葡萄糖苷; 4-二羟基苯基)-3-(BETA-D-吡喃葡萄糖氧基)-5; 矢车菊素 3- O -葡萄糖苷氯化物; 甲醇中矢车菊素-3-O-葡萄糖苷*10; 矢车菊素3-O-葡萄糖苷; 矢车菊素-3-O-葡萄糖苷氯化物; 矢车菊素-3-葡萄糖苷; 氯化苦马豆素; 矢车菊素-3-O-葡萄糖苷(标准品); 矢车菊素-3-O-葡 标准品; 矢车菊素-3-O-葡萄糖苷/面积归一化法; 矢车菊素-3-O-葡萄糖苷|花色苷; CYANIDIN-3-O-GLUCOSIDE CHLORIDE 矢车菊素-3-O-葡萄糖苷; 矢车菊素-3-O-葡萄糖苷-标准物质; 矢车菊素-3-O-葡萄糖苷/花青素; 矢车菊素-葡糖糖苷; 矢车菊素-3-O-葡萄糖苷/黄酮类
• 英文别名: 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)-3,4,5,6-tetrahydro-2H-pyran-2-yl]oxy}chromen-1-ium; (2S,3R,4S,5S,6R)-2-[2-(3,4-dihydroxyphenyl)-5,7-dihydroxychromenylium-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol,chloride; cyanidin3-o-glucoside; CYANIDIN3-O-BETA-D-GLUCOPYRANOSIDE; Kuromanin chloride, 10 mM in DMSO; ASTERIN hplc; Kuromanin; CYANIDIN-3-O-BETA-GLUCOPYRANOSIDE; Cyanidin 3-O-β-D-glucoside; Glucocyanidin chloride; Cyanidin-3-O-Glucoside Chloride (Kuromanin Chloride) (P); 1-Benzopyrylium, 2-(3,4-dihydroxyphenyl)-3-(β-D-glucopyranosyloxy)-5,7-dihydroxy-, chloride (1:1); CYANIDIN3-O-BETA-D-GLUCOSIDE; CYANIDIN-3-O-GLUCOSIDE CHLORIDE(KUROMANIN CHLORIDE)(SH); 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-3-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}chromeniumchlorid; KUROMANIN CHLORIDE; Chlorure de 2-(3,4-dihydroxyphényl)-5,7-dihydroxy-3-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxyméthyl)tétrahydro-2H-pyran-2-yl]oxy}chroménium; KUROMANINE CHLORIDE; ASTERIN; Asterin, Chrysanthemin, Cyanidin 3-O-glucoside chloride; Cyanidin 3-glucoside chloride-RM; KuroManin; Kuromanin chloride; cyanidin3-beta-glucoside; 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-3-chromeniumyl-β-D-glucopyranosidechlorid; chrysontemin; 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-3-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)chromenylium chloride; Jaceosidin Impurity 1; CYANIDIN-3-GLUCOSIDE; cyanidin-3-O-glu; cyanidine3-glucoside; Cyanidin-3-O-glucoside Chloride; KuroManine; 2-(3,4-Dihydroxyphenyl)-3-(.beta.-D-glucopyranosyloxy)-5,7-dihydroxy-1-benzopyryliumchloride; 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-3-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy}chromenium chloride; Cyanidin-3-O-Glucoside Chlorid; cyanidin 3-O-β-glucopyranoside chloride; 1-benzopyrylium,5,7-dihydroxy-2-(3,4-dihydroxyphenyl)-3-(beta-d-glucopyranosyl; Chrysontemin chloride; Cyanidin Chloride 3-Glucoside; Famitinib Impurity 12; CYANIDIN-3-GLUCOSIDE CHLORIDE; cyanidin3-O-β-D-glucoside; CYANIDIN-3-O-GLUCOSIDE CHLORIDE, KuroManin chloride; Cyanidin-3-O- glucoside chloride C-3-G; Cyanidin-3-O-glucoside chloride from Glycine max (L.) merr; 2- (3,4-dihydroxyphenyl) -5,7-dihydroxy-3- (((2S, 3R, 4S, 5S, 6R) -3,4,5-trihydroxy-6- (hydroxymethyl) tetrahydro-2H-pyran-2-yl) oxy) benzopyran chloride; glucocyanidin; Cyanidin 3-glucoside-RM; Cyanidin 3-O-β-D-glucopyranoside; cyanidol3-glucoside; Cyanidin-3-O-glucoside Chloride (15 mg); 1-BenzopyryliuM-2-(3,4-dihydroxyphenyl)-3-(b-D-glucopyranosyloxy)-5,7-dihydroxy-chloride; β-D-Glucopyranoside, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-1-benzopyrylium-3-yl, chloride (1:1); Kuromanin (chloride); 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxychromenium-3-yl β-D-glucopyranoside chloride; cyanidin 3-O-beta-D-glucoside; Cyanidin-3-O-glucoside chloride, froM GlycineMax (L.) Merr; 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-3-chromeniumyl β-D-glucopyranoside chloride; 1-BenzopyryliuM,2-(3,4-dihydroxyphenyl)-3-(b-D-glucopyranosyloxy)-5,7-dihydroxy-, chloride (1:1); CHRYSANTHEMIN; cyanidin3-monoglucoside; 6-anhydro-b-D-Glucose; Chlorure de β-D-glucopyranoside de 2-(3,4-dihydroxyphényl)-5,7-dihydroxy-3-chroméniumyle; CYANIDIN-3-O-GLUCOSIDE CHLORIDE(KUROMANIN CHLORIDE)(RG); Cyanidin 3-O-glucoside chloride

物化性质

• 分子式: C₂₁H₂₁ClO₁₁
• 分子量: 484.838
• 精确质量: 484.077240
• PSA: 193.44000
• 外观性状: 棕色 晶体 粉末
• 储存条件: −20°C

生物活性

• 描述: 矢车菊素-3-O-葡萄糖苷 (Kuromanin chloride) 来源于桑叶,具有提高血糖浓度、维持脂质代谢平衡以降低肥胖的作用。
• 相关类别:
  信号通路 >> 其他 >> 其他
  天然产物 >> 黄酮类化合物
  研究领域 >> 代谢疾病
• 参考文献:

  [1]. Ha -Na Na, et al. Reduction of adenovirus 36-induced obesity andin?ammation by mulberry extract. Microbiol Immunol 2014; 58: 303–306

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : DK1270000 CHEMICAL NAME : 1-Benzopyrylium, 5,7-dihydroxy-2-(3,4-dihydroxyphenyl)-3-(beta-D-gluco pyranosyloxy)-, chloride CAS REGISTRY NUMBER : 7084-24-4 LAST UPDATED : 199603 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C21-H21-O11.Cl MOLECULAR WEIGHT : 484.87 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 2 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #4229439

安全

• 个人防护装备: Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
• 危害码 (欧洲): Xi
• 安全声明 (欧洲): 24/25
• 危险品运输编码: NONH for all modes of transport
• RTECS号: DK1270000

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