71629-92-0

• 常用中文名：7-表-10-脱乙酰浆果赤霉素III
• 常用英文名：10-Deacetyl
• CAS号：71629-92-0
• 分子式：C₂₉H₃₆O₁₀
• 分子量：544.59
• 相关类别： 研究领域 癌症
• 发布时间：2017-05-07 08:29:23
• 更新时间：2026-07-01 10:59:47
• 7-epi-10-Deacetyl baccatin III 可从多西紫杉醇 (Docetaxel (HY-B0011)) 的降解杂质中分离出来。

名称

• 中文名: 7-表-10-脱乙酰浆果赤霉素III
• 英文名: 10-Deacetylbaccatine III
• 中文别名: 7-I-10-去乙酰浆果赤霉素; 多西他赛7-I-DAB-杂质; 紫杉醇杂质34; 7-表-10-去乙酰基巴卡亭Ⅲ; 10-脱乙酰基巴卡亭V(7-表-10-脱乙酰基巴卡亭III); 紫杉醇杂质6; 7-表-10-DAB; 7-表-10-去乙酰基浆果赤霉素III; 7-I-10-去乙酰浆果赤霉素 III; 10-脱乙酰基巴卡亭V
• 英文别名: 10-Deacetylbaccatin V (7-i-10-Deacetylbaccatin III); Docetaxel 7-i-DAB-Impurity; Paclitaxel Impurity 6; (2,4R,4aS,6R,9S,11S,12S,12,12bS)-12b-acetoxy-4,6,9,11-tetrahydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-12-yl ben; Paclitaxel impurity 1/7-i-10-Deacetyl-Baccatin III/Docetaxel 7-i-DAB-Impurity/(2,4R,4aS,6R,9S,11S,12S,12,12bS)-12b-(Acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dodecahydro-4,6,9,11-tetrahydroxy-4a,8,13,13-tetramethyl-7,11-methano-5; 7,11-Methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-one, 12b-(acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dodecahydro-4,6,9,11-tetrahydroxy-4a,8,13,13-tetramethyl-, (2,4R,4aS,6R,9S,11S,12S,12,12bS); 7-Table-10-DAB; (2,4R,4aS,6R,9S,11S,12S,12,12bS)-12b-acetoxy-4,6,9,11-tetrahydroxy-4a,8,13,13-tetramethyl-5-oxo-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-1H-7,11-methanocyclodeca[3,4]benzo[1,2-b]oxet-12-yl benzoate; (2,4R,4aS,6R,9S,11S,12S,12,12bS)-12b-(Acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dodecahydro-4,6,9,11-tetrahydroxy-4a,8,13,13-tetraMethyl-7,11-Methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-one; 7-i-10-deacetyl baccatinⅢ; 7-i-10-Deacetyl Baccatin III; 7-epi-10-Deacetyl Baccatin III; Paclitaxel Impurity 42

物化性质

• 分子式: C₂₉H₃₆O₁₀
• 分子量: 544.59
• 精确质量: 544.23100
• PSA: 159.82000
• LogP: 1.08180

生物活性

• 描述: 7-epi-10-Deacetyl baccatin III 可从多西紫杉醇 (Docetaxel (HY-B0011)) 的降解杂质中分离出来。
• 相关类别:
  研究领域 >> 癌症
  信号通路 >> 其他 >> 其他
• 参考文献:

  [1]. Kumar D, et al. Isolation and characterization of degradation impurities in docetaxel drug substance and its formulation. J Pharm Biomed Anal. 2007 Mar 12;43(4):1228-35.

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