77-03-2

• 常用中文名：Piperidione
• 常用英文名：Piperidione
• CAS号：77-03-2
• 分子式：C₉H₁₅NO₂
• 分子量：169.22100
• 相关类别： 分析化学 食品安全 脂肪酸、脂肪酸甲酯
• 发布时间：2017-01-28 00:37:40
• 更新时间：2025-08-20 18:20:51
• 哌啶酮是一种镇咳药[1]。

名称

• 英文名: 3,3-Diethylpiperidine-2,4-dione
• 英文别名: 3,3-diethyl-piperidine-2,4-dione; PIPERIDIONE; Sedilan; Nu 1510; Dihyprylon; Sedulon; Dihyprylone; Piperidion; Ascron; 3,3-Diaethyl-piperidin-2,4-dion; 3,3-Diethyl-2,4-dioxopiperidine

物化性质

• 密度: 1g/cm3
• 沸点: 337.7ºC at 760 mmHg
• 分子式: C₉H₁₅NO₂
• 分子量: 169.22100
• 闪点: 149.5ºC
• 精确质量: 169.11000
• PSA: 46.17000
• LogP: 1.21060
• 折射率: 1.447

生物活性

• 描述: 哌啶酮是一种镇咳药[1]。
• 相关类别:
  研究领域 >> 其他
  信号通路 >> 其他 >> 其他
• 参考文献:

  [1]. JACOBS S. The use of piperidione as a cough sedative. Med Times. 1948;76(10):445-447.

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : TM7345500 CHEMICAL NAME : 2,4-Piperidinedione, 3,3-diethyl- CAS REGISTRY NUMBER : 77-03-2 BEILSTEIN REFERENCE NO. : 0126810 LAST UPDATED : 199612 DATA ITEMS CITED : 2 MOLECULAR FORMULA : C9-H15-N-O2 MOLECULAR WEIGHT : 169.25 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 1100 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 193,219,1939 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Mammal - cat DOSE/DURATION : 1 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 193,219,1939

合成路线

77-04-3 ~% 77-03-2

文献：Bernhard et al. Helvetica Chimica Acta, 1954 , vol. 37, p. 1839,1854 Show Details Tsukita Yakugaku Zasshi, 1949 , vol. 69, p. 194 Chem.Abstr., 1950 , p. 1507 Show Details Hoffmann-La Roche Patent: DE637875 , 1935 ; Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 23, p. 464

74367-91-2 ~% 77-03-2

文献：Bernhard et al. Helvetica Chimica Acta, 1954 , vol. 37, p. 1839,1854

1619-57-4 ~% 77-03-2

文献：Tsukita Yakugaku Zasshi, 1949 , vol. 69, p. 194 Chem.Abstr., 1950 , p. 1507

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