106939-34-8

• 常用中文名：左氧氟环合酯
• 常用英文名：Ethyl (S)-9,10-difluoro-3-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylate
• CAS号：106939-34-8
• 分子式：C₁₅H₁₃F₂NO₄
• 分子量：309.265
• 发布时间：2018-06-17 18:12:39
• 更新时间：2024-01-03 08:15:29

名称

• 中文名: 左氧氟环合酯
• 英文名: ethyl (S)-(-)-9,10-Difluoro-3-Methyl-7-Oxo-2,3-Dihydro-7H-Pyrido[1,2,3-de]-[1,4]Benzoxazine-6-Carboxylate
• 中文别名: 左氧氟羧酸乙酯; 左氧氟沙星环合酯; (S)-9,10-二氟-3-甲基-7-氧代-2,3-二氢-7H-吡啶并[1,2,3-de]-1,4-苯骈恶嗪-6-羧酸乙酯
• 英文别名: Ethyl (S)-9,10-difluoro-3-methyl-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate; (S)-9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid Ethyl Ester; Levofiexacin acid ester; T666 1A M BN EO KVT&&J C1 Gf HF LVO2 &&S Form; 7H-1,4-Oxazino[2,3,4-ij]quinoline-6-carboxylic acid, 9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-, ethyl ester, (3S)-; (-)-ethyl 9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido<1,2,3-de><1,4>benzoxazine-6-carboxylate; ethyl (S)-(-)-9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylate; Ethyl (3S)-9,10-difluoro-3-methyl-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate; Levofloxacin cyclized ester; (S)-Ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate; 7H-Pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid, 9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-, ethyl ester, (3S)-; (S)-ethyl-9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido-[1,2,3-de]-1,4-benzoxazine-6-carboxylate; Levofloxacin Ethyl Ester

物化性质

• 密度: 1.4±0.1 g/cm3
• 沸点: 442.2±45.0 °C at 760 mmHg
• 熔点: 258-260ºC
• 分子式: C₁₅H₁₃F₂NO₄
• 分子量: 309.265
• 闪点: 221.2±28.7 °C
• 精确质量: 309.081268
• PSA: 57.53000
• LogP: 1.28
• 外观性状: 灰白色淡黄色固体
• 蒸汽压: 0.0±1.1 mmHg at 25°C
• 折射率: 1.582
• 储存条件: 室温，干燥

安全

• 海关编码: 2934999090

合成路线

106939-42-8 87-13-8 ~68% 106939-34-8

文献：EP368410 A3, ;

110548-02-2 ~% 106939-34-8

文献：WO2006/48889 A1, ; Page/Page column 16-17 ;

113472-54-1 ~74% 106939-34-8

文献：Chemical and pharmaceutical bulletin, , vol. 35, # 5 p. 1896 - 1902

91040-39-0 ~% 106939-34-8

文献：Chemical and pharmaceutical bulletin, , vol. 35, # 5 p. 1896 - 1902

100986-87-6 ~% 106939-34-8

文献：Chemical and pharmaceutical bulletin, , vol. 35, # 5 p. 1896 - 1902

100986-91-2 ~% 106939-34-8

文献：Chemical and pharmaceutical bulletin, , vol. 35, # 5 p. 1896 - 1902

106939-31-5 ~% 106939-34-8

文献：Chemical and pharmaceutical bulletin, , vol. 35, # 5 p. 1896 - 1902

上下游产品

上游产品  5
106939-42-8 87-13-8 110548-02-2 113472-54-1
106939-31-5
下游产品  1
100986-89-8

海关

海关编码	2934999090
中文概述	2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%