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901765-36-4

901765-36-4结构式
901765-36-4结构式

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中文名 (5S)-7-[4-(4-氟苯基)-6-异丙基-2-(N-甲基-N-甲磺酰基)嘧啶-5-yl]-5-羟基-3-氧代-6(E)-庚酸乙酯
英文名 ethyl (5S)-7-[4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-propan-2-ylpyrimidin-5-yl]-5-hydroxy-3-oxohept-6-enoate
中文别名 (5S,6e)-7-[4-(4-氟苯基)-6-(1-甲基乙基)-2-[甲基(甲基磺酰基)氨基]-5-嘧啶]-5-羟基-3-氧代-6-庚酸乙酯
瑞舒伐他汀钙中间体
英文别名 3-keto-5-hydroxy-ethyl rosuvastatin
3-keto-5-hydroxy rosuvastatin ethyl ester
(5S,6E)-7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-5-hydroxy-3-oxo-6-heptenoic acid ethyl ester
ethyl 7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrimidin-5-yl]-3-oxo-(5S)-5-hydroxy-(6E)-heptenoate
(S,E)-Ethyl 7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-5-hydroxy-3-oxohept-6-enoate
ethyl 6-(E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[N-methyl-N-methylsulfonylamino]pyrimidin-5-yl]-(5S)-hydroxy-3-oxoheptenoate
(S)-trans-ethyl 7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-5-hydroxy-3-oxohept-6-enoate
ethyl 7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrimidin-5-yl]-3-oxo-5(S)-hydroxy-6(E)-heptenoate
分子式 C24H30FN3O6S
分子量 507.57500
精确质量 507.18400
PSA 135.14000
LogP 4.16920

~88%

901765-36-4结构式

901765-36-4

文献:ASTRAZENECA UK LIMITED Patent: WO2007/7119 A1, 2007 ; Location in patent: Page/Page column 20 ; WO 2007/007119 A1

~92%

901765-36-4结构式

901765-36-4

文献:ASTRAZENECA UK LIMITED Patent: WO2008/65410 A1, 2008 ; Location in patent: Page/Page column 27 ; WO 2008/065410 A1

~64%

901765-36-4结构式

901765-36-4

文献:AUROBINDO PHARMA LIMITED Patent: WO2008/96257 A1, 2008 ; Location in patent: Page/Page column 21-24 ;
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