中文名 | (5S)-7-[4-(4-氟苯基)-6-异丙基-2-(N-甲基-N-甲磺酰基)嘧啶-5-yl]-5-羟基-3-氧代-6(E)-庚酸乙酯 |
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英文名 | ethyl (5S)-7-[4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-propan-2-ylpyrimidin-5-yl]-5-hydroxy-3-oxohept-6-enoate |
中文别名 |
(5S,6e)-7-[4-(4-氟苯基)-6-(1-甲基乙基)-2-[甲基(甲基磺酰基)氨基]-5-嘧啶]-5-羟基-3-氧代-6-庚酸乙酯
瑞舒伐他汀钙中间体 |
英文别名 |
3-keto-5-hydroxy-ethyl rosuvastatin
3-keto-5-hydroxy rosuvastatin ethyl ester (5S,6E)-7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-5-hydroxy-3-oxo-6-heptenoic acid ethyl ester ethyl 7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrimidin-5-yl]-3-oxo-(5S)-5-hydroxy-(6E)-heptenoate (S,E)-Ethyl 7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-5-hydroxy-3-oxohept-6-enoate ethyl 6-(E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[N-methyl-N-methylsulfonylamino]pyrimidin-5-yl]-(5S)-hydroxy-3-oxoheptenoate (S)-trans-ethyl 7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-5-hydroxy-3-oxohept-6-enoate ethyl 7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrimidin-5-yl]-3-oxo-5(S)-hydroxy-6(E)-heptenoate |
分子式 | C24H30FN3O6S |
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分子量 | 507.57500 |
精确质量 | 507.18400 |
PSA | 135.14000 |
LogP | 4.16920 |
~88% 901765-36-4 |
文献:ASTRAZENECA UK LIMITED Patent: WO2007/7119 A1, 2007 ; Location in patent: Page/Page column 20 ; WO 2007/007119 A1 |
~92% 901765-36-4 |
文献:ASTRAZENECA UK LIMITED Patent: WO2008/65410 A1, 2008 ; Location in patent: Page/Page column 27 ; WO 2008/065410 A1 |
~64% 901765-36-4 |
文献:AUROBINDO PHARMA LIMITED Patent: WO2008/96257 A1, 2008 ; Location in patent: Page/Page column 21-24 ; |
上游产品 2 | |
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下游产品 1 | |