851443-04-4

• 常用中文名：瑞舒伐他汀乙酯
• 常用英文名：Rosuvastatin ethyl ester
• CAS号：851443-04-4
• 分子式：C₂₄H₃₂FN₃O₆S
• 分子量：509.591
• 发布时间：2018-09-10 07:26:19
• 更新时间：2024-01-02 09:54:57

名称

• 中文名: 瑞舒伐他汀乙酯
• 英文名: (3R,5S,E)-Ethyl 7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido) pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoate
• 中文别名: 罗苏伐他汀乙酯; 7-[4-(4-氟苯基)-6-异丙基-2-(N-甲基-N-甲磺酰氨基)嘧啶-5-基]-3,5－二羟基-6(E)-庚烯酸乙酯
• 英文别名: 6-Heptenoic acid, 7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-, ethyl ester, (3R,5S,6E)-; (E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]-pyrimidin-5-yl](3R,5S)-3,5-dihydroxyhept-6-enoic acid ethyl ester; (3R,5S,6E)-7-[4-(4-fluorophenyl)-6-(1-methylethyl)]-2-[methyl(methylsulfonyl)amino-5-pyrimidinyl]-3,5-dihydroxy-6-heptenoic acid ethyl ester; (E)-(+)-7-[4-(4-fluorophenyl)-6-isopropyl-2-(methansulfonyl-methylamino)-pyrimidin-5-yl]-(3R,5S)-dihydroxy-hept-6-enoate ethyl ester; (+)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(methanesulfonyl-methyl-amino)-pyrimidin-5-yl)-(3R,5S,6E)-dihydroxy-hept-6-enoic acid ethyl ester; ethyl (3R,5S,6E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoate; Rosuvastatin Ethyl Ester; ethyl (3R,5S,6E)-7-[4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-(propan-2-yl)pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoate; Ethyl (3R,5S,6E)-7-{4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl}-3,5-dihydroxyhept-6-enoate; Ethyl (3R,5S,6E)-7-{4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl}-3,5-dihydroxy-6-heptenoate; 7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-(N-methyl-N-methylsulfonyl-amino)-pyrimidin-5-yl]-3,5-dihydroxy-hept-6-enoic acid ethyl ester; (+)-ethyl 7-[4-(4-fluorophenyl)-6-isopropyl-2-(N-methyl-N-methylsulfonylamino)pyrimidin-5-yl]-(3R,5S)-3,5-dihydroxy-6(E)-heptenoate

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 699.1±65.0 °C at 760 mmHg
• 分子式: C₂₄H₃₂FN₃O₆S
• 分子量: 509.591
• 闪点: 376.6±34.3 °C
• 精确质量: 509.199585
• PSA: 138.30000
• LogP: 1.54
• 蒸汽压: 0.0±2.3 mmHg at 25°C
• 折射率: 1.571

安全

• 海关编码: 2942000000

合成路线

901765-36-4 ~99% 851443-04-4

文献：AUROBINDO PHARMA LIMITED Patent: WO2008/96257 A1, 2008 ; Location in patent: Page/Page column 24 ;

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海关

海关编码	2942000000