53772-85-3

• 常用中文名：TRANS-(E)-FLUPENTHIXOL
• 常用英文名：TRANS-(E)-FLUPENTHIXOL
• CAS号：53772-85-3
• 分子式：C₂₃H₂₅F₃N₂OS
• 分子量：434.51800
• 发布时间：2016-05-22 18:08:30
• 更新时间：2026-08-02 19:49:09

名称

• 英文名: 2-[4-[(3E)-3-[2-(trifluoromethyl)thioxanthen-9-ylidene]propyl]piperazin-1-yl]ethanol
• 英文别名: 1-Piperazineethanol, 4-(3-(2-(trifluoromethyl)-9H-thioxanthen-9-ylidene)propyl)-, (E); (e)-flupenthixol; trans-(e)-flupentixol; (E)-4-(3-(2-(Trifluoromethyl)-9H-thioxanthen-9-ylidene)propyl)-1-piperazineethanol; Einecs -0; trans-flupentixol; EINECS 258-759-0; FLUPENTHIXOL; beta-flupenthixol; 4-[3-[(E)-2-Trifluoromethyl-9H-thioxanthen-9-ylidene]propyl]-1-piperazineethanol; trans-Flupentixol; trans-flupenthixol; (e)-4-(3-(2-(trifluoromethyl)-9h-thioxanthen-9-ylidene)propyl)-1-piperazinee; FLUPENTIXOLE; 1-Piperazineethanol, 4-[(3E)-3-[2-(trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl]; TRANS -(E)-FLUPENTHIXOL; (E)-4-[3-[2-(trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl]piperazine-1-ethanol; Flupentixol trans-Isomer

物化性质

• 密度: 1.306 g/cm3
• 沸点: 289.3ºC
• 分子式: C₂₃H₂₅F₃N₂OS
• 分子量: 434.51800
• 精确质量: 434.16400
• PSA: 52.01000
• LogP: 4.47750

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : TL9902000 CHEMICAL NAME : 1-Piperazineethanol, 4-(3-(2-(trifluoromethyl)-9H-thioxanthen-9-ylidene)pr opyl)-, (E)- CAS REGISTRY NUMBER : 53772-85-3 LAST UPDATED : 199103 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C23-H25-F3-N2-O-S MOLECULAR WEIGHT : 434.56 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : >400 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 23,884,1980

合成路线

103-76-4 28973-34-4 ~% 2709-56-0 53772-85-3

文献：LABORATORIO CHIMICO INTERNAZIONALE S.P.A. Patent: WO2005/37820 A1, 2005 ; Location in patent: Page/Page column 8-9 ;

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