516-41-6

• 常用中文名：11-Beta,17-alpha,21-三羟基-5-alpha-孕烯-3,20-二酮
• 常用英文名：11-BETA,17-ALPHA,21-TRIHYDROXY-5-ALPHA-PREGNANE-3,20-DIONE
• CAS号：516-41-6
• 分子式：C₂₁H₃₂O₅
• 分子量：364.47600
• 发布时间：2019-01-01 18:04:34
• 更新时间：2025-08-30 14:06:57

名称

• 中文名: 11-Beta,17-alpha,21-三羟基-5-alpha-孕烯-3,20-二酮
• 英文名: (5α,11β)-11,17,21-Trihydroxypregnane-3,20-dione
• 中文别名: 5Α-二氢皮质醇; 甲醇中5Α-二氢皮质醇; 5Α-二氢皮质醇(溶液)
• 英文别名: 5-dihydrocortisol; 11Beta,17Alpha,20Alpha,21-Tetrahydroxy-21-acetoxy-3-oxo-pregnadien-(1,4); Hydra11ostane; 5α-Dihydrocortisol (solution); ALLODIHYDROCORTISOL; (17R)-17-glycoloyl-11,17-dihydroxy-10,13-dimethyl-2,4,5,6,7,8,9,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-3-one; Pregnane-3,20-dione, 11,17,21-trihydroxy-, (5α,11β); (17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,4,5,6,7,8,9,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-3-one; 11β, 17α, 21-Trihydroxy-5α-Pregnane-3, 20-Dione; 5-ALPHA-PREGNAN-11-BETA, 17,21-TRIOL-3,20-DIONE; (17R)-11,17-dihydroxy-17-(2-hydroxyethanoyl)-10,13-dimethyl-2,4,5,6,7,8,9,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-3-one; 5α-Dihydrocortisol in Methanol; 5A-pregnane-11B,17A,21-triol-3,20-*dione; 5α-PREGNAN-11β, 17, 21-TRIOL-3, 20-DIONE; 5Alpha-Dihydrocortisol; 5ALPHA-PREGNAN-11BETA,17ALPHA,21-TRIOL-3,20-DIONE; Allopregnane-11β,17α,21-triol-3,20-dione; 5α-Pregnan-11β,17α,21-triol-3,20-dione; Allodihydro F; 5-ALPHA-DIHYDROCORTISOL; 11β,17,21-Trihydroxy-5α-pregnane-3,20-dione; 5α-Dihydrocortisol; 4,5α-Dihydrocortisol

物化性质

• 密度: 1.249g/cm3
• 沸点: 544.5ºC at 760mmHg
• 分子式: C₂₁H₃₂O₅
• 分子量: 364.47600
• 闪点: 297.1ºC
• 精确质量: 364.22500
• PSA: 94.83000
• LogP: 1.86150
• 折射率: 1.569

合成路线

4004-68-6 ~91% 516-41-6

文献：Okihara, Rika; Mitamura, Kuniko; Hasegawa, Maki; Mori, Megumi; Muto, Akina; Kakiyama, Genta; Ogawa, Shoujiro; Iida, Takashi; Shimada, Miki; Mano, Nariyasu; Ikegawa, Shigeo Chemical and Pharmaceutical Bulletin, 2010 , vol. 58, # 3 p. 344 - 353

50-23-7 ~60% 516-41-6

文献：Holland, Herbert L. Steroids, 1995 , vol. 60, # 9 p. 646 - 649

50-03-3 ~% 516-41-6

文献：Hosoda; Osanai; Fukasawa; Nambara Chemical and Pharmaceutical Bulletin, 1990 , vol. 38, # 7 p. 1949 - 1952

56736-68-6 ~% 516-41-6

文献：Hosoda; Osanai; Fukasawa; Nambara Chemical and Pharmaceutical Bulletin, 1990 , vol. 38, # 7 p. 1949 - 1952

50-23-7 ~% 516-41-6 1482-50-4

文献：Ramachary, Dhevalapally B.; Sakthidevi, Rajasekar; Reddy, P. Srinivasa RSC Advances, 2013 , vol. 3, # 32 p. 13497 - 13506

117899-28-2 ~% 516-41-6

文献：Evans et al. Journal of the Chemical Society, 1958 , p. 1529,1536

1482-51-5 ~% 516-41-6

文献：Evans et al. Journal of the Chemical Society, 1958 , p. 1529,1536

3751-02-8 ~% 516-41-6

文献：Evans et al. Journal of the Chemical Society, 1958 , p. 1529,1536

117888-55-8 ~% 516-41-6

文献：Evans et al. Journal of the Chemical Society, 1958 , p. 1529,1536

上下游产品

上游产品  8
4004-68-6 50-23-7 50-03-3 56736-68-6
117899-28-2 1482-51-5 3751-02-8 117888-55-8
下游产品  1
4004-68-6