66000-41-7

• 常用中文名：3-氨基-1-(3-三氟甲基苯基)吡唑
• 常用英文名：1-[3-(Trifluoromethyl)phenyl]-1H-pyrazol-3-amine
• CAS号：66000-41-7
• 分子式：C₁₀H₈F₃N₃
• 分子量：227.18600
• 发布时间：2018-10-20 10:40:57
• 更新时间：2024-01-10 21:05:39

名称

• 中文名: 3-氨基-1-(3-三氟甲基苯基)吡唑
• 英文名: 1-[3-(Trifluoromethyl)phenyl]-1H-pyrazol-3-amine
• 英文别名: Urea,N-phenyl-N'-[3-(triethoxysilyl)propyl]; 1-(3-(triethoxysilyl)propyl)-3-phenyl urea; 1-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3-amine; 1-(3-trifluoromethyl-phenyl)-1H-pyrazol-3-ylamine; 1-m-Trifluormethylphenyl-3-aminopyrazol

物化性质

• 分子式: C₁₀H₈F₃N₃
• 分子量: 227.18600
• 精确质量: 227.06700
• PSA: 44.57000
• LogP: 2.40340

合成路线

1354722-12-5 ~98% 66000-41-7

文献：ARDELYX, INC.; LEWIS, Jason, G.; JACOBS, Jeffrey, W.; REICH, Nicholas; LEADBETTER, Michael, R.; BELL, Noah; CHANG, Han-Ting; CHEN, Tao; NAVRE, Marc; CHARMOT, Dominique; CARRERAS, Christopher; LABONTE, Eric Patent: WO2012/6473 A1, 2012 ; Location in patent: Page/Page column 70 ; WO 2012/006473 A1

66000-40-6 ~% 66000-41-7

文献：GLENMARK PHARMACEUTICALS S.A.; KUMAR, Sukkeerthi; THOMAS, Abraham; WAGHMARE, Nayan, Taterao; KHAIRATKAR-JOSHI, Neelima; MUKHOPADHYAY, Indranil Patent: WO2011/132017 A1, 2011 ; Location in patent: Page/Page column 24-25 ; WO 2011/132017 A1

401-81-0 ~% 66000-41-7

文献：ARDELYX, INC.; LEWIS, Jason, G.; JACOBS, Jeffrey, W.; REICH, Nicholas; LEADBETTER, Michael, R.; BELL, Noah; CHANG, Han-Ting; CHEN, Tao; NAVRE, Marc; CHARMOT, Dominique; CARRERAS, Christopher; LABONTE, Eric Patent: WO2012/6473 A1, 2012 ; WO 2012/006473 A1

368-78-5 ~% 66000-41-7

文献：GLENMARK PHARMACEUTICALS S.A.; KUMAR, Sukkeerthi; THOMAS, Abraham; WAGHMARE, Nayan, Taterao; KHAIRATKAR-JOSHI, Neelima; MUKHOPADHYAY, Indranil Patent: WO2011/132017 A1, 2011 ; WO 2011/132017 A1