106401-68-7

• 常用中文名：(8S,10S)-10-[(3-氨基-2,3,6-三脱氧-ALPHA-L-吡喃来苏己糖基)氧基]-8-(2-溴-1,1-二甲氧基乙基)-7,8,9,10-四氢-6,8,11-三羟基-1-甲氧基-5,12-并四苯醌
• 常用英文名：(7S,9S)-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-9-(2-bromo-1,1-dimethoxyethyl)-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione
• CAS号：106401-68-7
• 分子式：C₂₉H₃₄BrNO₁₁
• 分子量：652.48400
• 发布时间：2016-08-02 05:30:03
• 更新时间：2026-08-30 12:00:31

名称

• 中文名: (8S,10S)-10-[(3-氨基-2,3,6-三脱氧-ALPHA-L-吡喃来苏己糖基)氧基]-8-(2-溴-1,1-二甲氧基乙基)-7,8,9,10-四氢-6,8,11-三羟基-1-甲氧基-5,12-并四苯醌
• 英文名: (7S,9S)-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-9-(2-bromo-1,1-dimethoxyethyl)-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione
• 中文别名: DOXORUBICIN KETAL 杂质; (8S,10S)-10-(((2R,4S,5S,6S)-4-氨基-5-羟基-6-甲基四氢-2H-吡喃-2-基)氧基)-8-(2-溴- 1,1-二甲氧基乙基)-6,8,11-三羟基-1-甲氧基-7,8,9,10-四氢并四苯-5,12-二酮 (多柔比星杂质); 多柔比星杂质B; 阿霉素杂质2(阿霉素杂质B); 表柔比星溴缩酮; 阿霉素杂质B; 多柔比星杂质02(单体); 盐酸多柔比星杂质B
• 英文别名: Doxorubicin Hydrochloride impurity B; Doxorubicin Impurity B; Doxorubicin Ketal Derivative; Doxorubicin Ketal Impurity; 5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-8-(2-bromo-1,1-dimethoxyethyl)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-, (8S,10S); (8S,10S)-10-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-8-(2-broMo-1,1-diMethoxyethyl)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-Methoxy-5,12-naphthacenedione (Doxorubicin IMpurity); UNII-3Z1AE1LY2D; (8S,10S)-10-(((2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-8-(2-bromo-1,1-dimethoxyethyl)-6,8,11-trihydroxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione; (8S,10S)-10-(((2R,4S,5S,6S)-4-Amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-8-(2-bromo-1,1-dimethoxyethyl)-6,8,11-trihydroxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione (Doxorubicin Impurity); (8S,10S)-10-[(3-Amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-8-(2-bromo-1,1-dimethoxyethyl)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione; Doxorubicin Impurity 2（Doxorubicin Impurity B）; (8S,10S)-10[(3-Amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-8-(2-bromo-1,1-dimethoxyethyl)-6,8,11-trihydroxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione; Daunorubicin bromoketal; Daunorubicin bromo dimethyl ketal; 14-bromo-13-dimethylketal-daunorubicin

物化性质

• 分子式: C₂₉H₃₄BrNO₁₁
• 分子量: 652.48400
• 精确质量: 651.13200
• PSA: 187.23000
• LogP: 2.52420

合成路线

23541-50-6 149-73-5 ~% 106401-68-7

文献：Meyer-Losic, Florence; Quinonero, Jerome; Dubois, Vincent; Alluis, Bertrand; Dechambre, Mireille; Michel, Matthieu; Cailler, Francoise; Fernandez, Anne-Marie; Trouet, Andre; Kearsey, Jonathan Journal of Medicinal Chemistry, 2006 , vol. 49, # 23 p. 6908 - 6916

67-56-1 23541-50-6 ~% 106401-68-7

文献：Olsufyeva, Eugenia N.; Tevyashova, Anna N.; Trestchalin, Ivan D.; Preobrazhenskaya, Maria N.; Platt, David; Klyosov, Anatole Carbohydrate Research, 2003 , vol. 338, # 13 p. 1359 - 1367

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