1012341-50-2

• 常用中文名：(2R,4S)-5-(联苯-4-基)-4-[(叔丁氧羰基)氨基]-2-甲基戊酸
• 常用英文名：(2R,4S)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid
• CAS号：1012341-50-2
• 分子式：C₂₃H₂₉NO₄
• 分子量：383.481
• 相关类别： 有机原料 羧酸类化合物及衍生物 环羧酸
• 发布时间：2019-01-09 19:21:33
• 更新时间：2026-07-09 12:17:53

名称

• 中文名: (2R,4S)-5-(联苯-4-基)-4-[(叔丁氧基羰基)氨基]-2-甲基戊酸
• 英文名: (2R,4S)-5-([1,1-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoic acid
• 中文别名: 沙库必曲-须沙坦水合物; 塞克比曲标准品-SS; 沙库比曲缬沙坦/LCZ696中间体/(2R,4S)-5-(联苯-4-基)-4-[(叔丁氧基羰基)氨基]-2-甲基戊酸; LCZ696 医药中间体Ⅰ; 沙库巴曲缬沙坦中间体; 沙库比曲缬沙坦/(2R,4S)-5-(联苯-4-基)-4-[(叔丁氧基羰基)氨基]-2-甲基戊酸; (2R,4S)-5-(BIPHENYL-4-YL)-4-[(TERT-BUTOXYCBONYL)AMI O]-2-METHYLPENTANOIC ACID(2R,4S)-5-(联苯-4-基)-4-[(叔丁氧基羰基)氨基]-2-甲基戊酸[DMF NO. 031502]; 沙库比曲缬沙坦(LCZ696)中间体; LCZ696杂质; 1)(2R,4S)-5-(联苯-4-基)-4-[(叔丁氧基羰基)氨基]-2-甲基戊酸; 2-氯噻吩-5-甲酸(2R,4S)-5-(联苯-4-基)-4-[(叔丁氧基羰基)氨基]-2-甲基戊酸; LCZ696杂质547-06对照品; (2R,4S)-5-([1,1'-联苯]-4-基)-4-((叔丁氧羰基)氨基)-2-甲基戊酸; ((S)-N-戊酰基-{[2-(1H-四唑-5-基)-联苯-4-基]-甲基}-缬氨酸)((2R,4S)-5-(联苯-4-基)-4-(氨基)-5-(3-羧基-丙酰基氨基)-2-甲基-戊酸乙酯)三钠半五水合物; 4S)-5-(联苯-4-基)-4-[(叔丁氧基羰基)氨基]-2-甲基戊酸; 沙库巴曲钙杂质24; (2R,4S)-5-(联苯-4-基)-4-[(叔丁氧基羰基)氨基]-2-甲基戊酸/(2R,4S)-5-([1,1'-BIPHENYL]-4-YL)-4-((TERT-BUTOXYCBONYL)AMINO)-2-METHYLPENTANOIC ACID; LCZ969中间体; (2R,4S)-5-(联苯基-4-基)-4-[(叔丁氧羰基)氨基]-2-甲基戊酸; 沙库巴曲杂质27; 缬沙坦杂质80; (2E,4S)-5-(联苯-4-基)-4-[(叔丁氧基羰基)氨基]-2-甲基-2-戊烯酸; 沙库巴曲缬沙坦钠中间体; LCZ696(ENTRESTO)中间体甲基戊酸; LCZ696中间体1/(R)-叔丁基 (1-([1,1'-联苯]-4-基)-3-羟基丙烷-2-基)氨基甲酸酯; (2R,4S)-5-(联苯-4-基)-4-[(叔丁氧基羰基); SACUBITRIL 杂质8; (2R,4S)-5-(联基-4-基)-4-[(叔丁氧基羰基)氨基]-2-甲基戊酸; (2R,4S)-5-(联苯-4-基)-4-[(叔丁氧基羰基)氨基]-2-甲基戊酸 LCZ696中间体; (2R,4S)-5-(4-联苯基)-4-(BOC-氨基)-2-甲基戊酸; (2R,4S)-5-(联苯-4-基)-4-[(叔丁氧基羰基)氨基]-2-甲基戊酸 LCZ中间体III; LCZ-696中间体40; 沙必比尔杂质8; 沙库必曲(LCZ696)杂质17; (2R,4S)-5-(联苯-4-基)-4-[(叔丁氧基羰基)氨基]-2-甲基戊酸1012-2 LCZT; LCZ-696中间体三; LCZ696中间体-1,(2R,4S)-5-(联苯-4-基)-4-[(叔丁氧羰基)氨基]-2-甲基戊酸; LCZ696-中间体; LCZ696中间体; (2R,4S)-5-(联苯-4-基)-4-[(叔丁氧基羰基)氨基]-2-甲基戊酸(中...); (2R,4S)-5-([1,1′-联苯]-4-基)-4-((叔丁氧羰基)氨基)-2-甲基戊酸; (2R,4S)-5-([1,1'-联苯]-4-基)-4-((叔丁氧羰基)氨基)-2-甲基戊酸 中文名称 (2R,4S)-5-([1,1'-联苯]-4-基)-4-((叔丁氧羰基)氨基)-2-甲基戊酸 英; LCZ-696中间体40(R,R); LCZ696 中间体N-3; (2R,4S)-5-([1,1'-联苯]-4-基)-4-(BOC-氨基)-2-甲基戊酸; 原研; 沙库巴曲缬沙坦杂质52; LCZ696中间体2; (2R,4S)-5-(联苯-4-基)-4-[(叔丁氧基羰基)氨]-2-甲基戊酸; (2R,4S)-5-(联苯-4-基)-4-[（叔丁氧羰基）氨基]-2-甲基戊酸; LCZ696中间体AHU; ENTRESTO中间体; Sacubitril(LCZ696)中间体; LCZ696中间体,(2R,4S)-5-([1,1'-联苯]-4-基)-4-((叔丁 氧羰基)氨基)-2-甲基戊酸
• 英文别名: (2R,4S)-5-[Biphenyl-4-(tert-butoxycbonyl)amino]-2-methylpentanoicacid; LCZ696 impurities123; [1,1'-Biphenyl]-4-pentanoicacid,γ-[[(1,1-dimethylethoxy)carbonyl]amino]-α-methyl-,(αR,γS); (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxy; (2R,4S)-5-(Biphenyl-4-yl)-4-[(tert-butoxycbonyl)amino]-2-Methylpentanoic acid; LCA696 inter; (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycbonyl)amino)-2-Methylpentanoic; LCZ-696-001-SS; AHU08; LCZ696 Intermediate N-3; [1,1'-Biphenyl]-4-pentanoic acid, γ-[[(1,1-dimethylethoxy)carbonyl]amino]-α-methyl-, (αR,γS); Entresto intermediate N-3; (2R,4S)-5-(Biphenyl-4-yl)-4-[(tert-butoxycbonyl)amino]-2-methylpentanoic acid [DMF No. 031502]; Valstan Impurity 80; LCZ-696 Intermediate 40(R,R); (2R,4S)-5-(4-Biphenylyl)-2-methyl-4-({[(2-methyl-2-propanyl)oxy]carbonyl}amino)pentanoic acid; sacubitril intermediate; 4S)-5-([1; (2R, 4S) -5- ([1,1'-]-4- based -4- (biphenyl) (TERT butoxycbonyl) amino) -2- methyl valerate; Propanoicacid,3-cyano-2-[[(1,1-dimethylethoxy)carbonyl]amino]-,(7S); 1,1'-Biphenyl]-4-pentanoic acid, γ-[[(1,1-dimethylethoxy)carbonyl]amino]-α-methyl-, (αR,γS); LCZ696S-01; (2R,4S)-5-(Biphenyl-4-yl)-4-[(tert-butoxycbonyl)amino]-2-methylpentanoic acidQ: What is (2R,4S)-5-(Biphenyl-4-yl)-4-[(tert-butoxycbonyl)amino]-2-methylpentanoic acid Q: What is the CAS Number of (2R,4S)-5-(Biphenyl-4-yl)-4-[(tert-butoxycbonyl)amino]-2-methylpentanoic acid Q: What is the storage condition of (2R,4S)-5-(Biphenyl-4-yl)-4-[(tert-butoxycbonyl)amino]-2-methylpentanoic acid Q: What e the applications of (2R,4S)-5-(Biphenyl-4-yl)-4-[(tert-butoxycbonyl)amino]-2-methylpentanoic acid; (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycbonyl)amino)-2; (2R,4S)-5-((2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycbonyl)amino)-2-Methylpentanoic acid; (2R,4S)-5-(Biphenyl-4-yl)-4-[(tert-butoxycbonyl)amino]-2-meth; Sacubitril-Valstan Hydrate; (2R,4S)-2-methyl-4-[(2-methylpropan-2-yl)oxycbonylamino]-5-(4-phenylphenyl)pentanoic acid; 1'-biphenyl]-4-yl)-4-((tert-butoxycbonyl)amino)-2-Methylpentanoic acid; (2R,4S)-5-(4-Biphenylyl)-4-[(tert-butoxycbonyl)amino]-2-methylpentanoicacid; LCZ696 inter; (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycbonyl)ami; (αR,γS)-γ-[[(1,1-Dimethylethoxy)carbonyl]amino]-α-methyl[1,1'-biphenyl]-4-pentanoic acid; LCZ-696 Intermediate 40; LCZ696 intermediates，(2R,4S)-5-([1,1'-biphenyl]-4-yl)-4- ((tert-butoxycbonyl)amino)-2- methylpentanoic acid; (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)amino)-2-methylpentanoic acid; (2R,4S)-5-([1,1'-Biphenyl]-4-yl)-4-((tert-butoxycbonyl)amino)-2-methylpentanoic acid; (2R,4S)-5-(4-Biphenylyl)-4-(Boc-amino)-2-methylpentanoic Acid; LCZ696 INT; Salcubatra calcium impurity 14; (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycbonyl)amino)-2-Methylpentanoic acid ISO 9001：2015 REACH; the intermidiate of AHU-377; SACUBITRIL N-BOC ACID (SAV-2); (2R,4S)-5-(biphenyl-4-base)-4-[(tert-Butoxycbonyl)amino ]-2-Methylvaleric acid; (2R,4S)-5-([1,1'-biphenyl]-4-y1)-4-((tert-butoxycbonyl) amino)-2-methylpentanoic acid; Sacubitril intermediates (2R,4S)-5-(Biphenyl-4-yl)-4-[(tert-butoxycbonyl)amino]-2-methylpentanoic acid; (2R,4S)-5-(Biphenyl-4-yl)-4-(tert-butoxycbonylamino)-2-methylpentanoic acid (Intermediate of Sacubitril Valstan Sodium); 2-PYRIMIDINEMETHANOL,7-HYDROXY; LCZ696 valstan + sacubitril Impurity 52; (2R,4S)-5-(Biphenyl-4-yl)-4-[(tert-butoxycbonyl) amino]-2-methylpentanoic acid AHU84; (2R, 4S) -5- (biphenyl-4-yl) -4-[(tert-butoxycbonyl) amino] -2-methylvaleric acid; (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycbonyl)amino)-2-methylpentanoic aci

物化性质

• 密度: 1.1±0.1 g/cm3
• 沸点: 582.6±50.0 °C at 760 mmHg
• 分子式: C₂₃H₂₉NO₄
• 分子量: 383.481
• 闪点: 306.2±30.1 °C
• 精确质量: 383.209656
• PSA: 75.63000
• LogP: 5.25
• 蒸汽压: 0.0±1.7 mmHg at 25°C
• 折射率: 1.546
• 储存条件: 2-8°C，干燥密封
• 水溶解性: Insuluble (3.1E-3 g/L) (25 ºC)