2461-42-9

• 常用中文名：3-(1-萘氧基)-1,2-环氧丙烷
• 常用英文名：UNII:07FN14F351
• CAS号：2461-42-9
• 分子式：C₁₃H₁₂O₂
• 分子量：200.233
• 发布时间：2018-11-28 19:20:11
• 更新时间：2026-07-02 00:35:10
• 【用途一】
  心得安的中间体。

名称

• 中文名: 3-(1-萘氧基)-1,2-环氧丙烷
• 英文名: α-Naphthyl Glycidyl Ether
• 中文别名: 2-[(1-萘基氧基)甲基]环氧乙烷; 丙醇杂质6; 盐酸普萘洛尔杂质 标准品; 1-萘甲酚缩水甘油醚; 萘哌地尔/3-(1-萘氧基)-1,2-环氧丙烷; 2-((萘-1-基氧基)甲基)环氧乙烷; 3-(Α-萘氧基)-1,2环氧丙烷; 萘基缩水甘油醚; 萘缩水甘油醚; 普萘洛尔P2标准; 萘哌地尔杂质1; 盐酸普萘洛尔中间体1; 盐酸普萘洛尔中间体; 3-(1-萘氧基)-1,2-环氧丙烷(市场价低); 盐酸普萘洛尔杂质7
• 英文别名: 3-(1-Naphthalenyloxy)-1,2-Cycl; ALPHA-NAPHTHYLGLYCIDYLETHER; Propranolol Impurity 7; (1-Naphtyl)glycidyl ether; 1-(2,3-oxypropoxy)-naphthalen; [(1-Naphthalenyloxy)methyl]oxirane; Product NaMe 1-Naphthol Glycidyl Ether 3-(1-Naphthy; Propranolol P2 Std; [(naphthyloxy)methyl]oxirane; 3-(1-naphthyloxy)-1,2-oxypropane; 1-(2,3-oxypropoxy)naphthalene; (2S)-2-(1-naphthalenyloxymethyl)oxirane; 2-[(1-Naphthyloxy)methyl]oxirane; 3-(1-Naphthoxy)-1,2-epoxypropane; 1-naphthylglycidylether; ether,2,3-oxypropyl1-naphthyl; [(1-Naphtyloxy)methyl]oxirane; Naftopidil Impurity 1; EINECS 219-555-7; 2-[(1-NAPHTHYLOXY)METHYL]OXIRANE; 3-(1-NAPHTHALENYLOXY)-1,2-CYCLOPROPANE(NAFTOPIDIL INTERMEDIATE); Glycidyl naphthyl ether; NAPHTHYL GLYCIDYL ETHER; (+/-)-1-(1-Naphthyloxy)-2,3; Naphthyl Glycidyl Ethe; 1,2-oxy-3-(1-naphthoxy)-propane; OXY IMPURITY; 2-[(naphthalen-1-yloxy)methyl]oxirane; 2-[(1-Naphtyloxy)methyl]oxirane; 1-(ALPHA-NAPHTHALENOXY)-2,3-OXYPROPANE; Propanolol Impurity 6; 1-Naphtylglycidyl ether; Oxirane, 2-[(1-naphthalenyloxy)methyl]; MFCD00055643; UNII:07FN14F; glycidyl1-naphthylether; 2-(1-Naphtyloxymethyl)oxirane; Propranolol oxide impurity; 1-NAPHTHOL GLYCIDYL ETHER; 3-(1-Naphthoxy)-1,2-oxypropane; Propranolol oxide; 1-(1-Naphthyloxy)-2,3-oxypropane; 2-[(1-Naphthalenyloxy)Methyl]oxirane; A-NAPHTHYL GLYCIDYL ETHER

物化性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 338.6±0.0 °C at 760 mmHg
• 分子式: C₁₃H₁₂O₂
• 分子量: 200.233
• 闪点: 152.0±19.9 °C
• 精确质量: 200.083725
• PSA: 21.76000
• LogP: 2.97
• 外观性状: 淡紫色油状
• 蒸汽压: 0.0±0.7 mmHg at 25°C
• 折射率: 1.629
• 储存条件: Refrigerator

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : QJ6873000 CHEMICAL NAME : Naphthalene, 1-(2,3-epoxypropoxy)- CAS REGISTRY NUMBER : 2461-42-9 BEILSTEIN REFERENCE NO. : 0160552 LAST UPDATED : 199612 DATA ITEMS CITED : 7 MOLECULAR FORMULA : C13-H12-O2 MOLECULAR WEIGHT : 200.25 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : Mutation test systems - not otherwise specified TYPE OF TEST : Cytogenetic analysis TYPE OF TEST : Sister chromatid exchange MUTATION DATA TEST SYSTEM : Rodent - mouse DOSE/DURATION : 50 mg/kg REFERENCE : EMMUEG Environmental and Molecular Mutagenesis. (Alan R. Liss, Inc., 41 E. 11th St., New York, NY 10003) V.10- 1987- Volume(issue)/page/year: 22,71,1993

安全

• 海关编码: 2910900090

合成路线

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制备

【方法一】
将α-萘酚与环氧氯丙烷加热反应，醚化后生成1-氯-3-（1-萘氧基）-2-丙醇，然后在氢氧化钠作用下脱除氯化氢得到该品。

海关

海关编码	2910900090
中文概述	2910900090. 三节环环氧化物，环氧醇（酚，醚），包括其卤化，磺化，硝化或亚硝化的衍生物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:5.5%. 普通关税:30.0%
申报要素	品名, 成分含量, 用途
Summary	2910900090. epoxides, epoxyalcohols, epoxyphenols and epoxyethers, with a three-membered ring, and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%