10476-53-6

• 常用中文名：(+/-)-4-hydroxypropranolol, hydrochloride
• 常用英文名：(+/-)-4-hydroxypropranolol, hydrochloride
• CAS号：10476-53-6
• 分子式：C₁₆H₂₂ClNO₃
• 分子量：311.80400
• 发布时间：2016-08-18 17:54:19
• 更新时间：2024-01-10 20:11:58

名称

• 英文名: (+/-)-4-hydroxypropranolol, hydrochloride
• 英文别名: 4-hydroxypranolol; 4-hydroxypropranol; 4-OH-propranolol; rac-4'-hydroxypropranolol

物化性质

• 密度: 1.168g/cm3
• 沸点: 487.5ºC at 760mmHg
• 熔点: 167-169ºC
• 分子式: C₁₆H₂₂ClNO₃
• 分子量: 311.80400
• 闪点: 248.6ºC
• 精确质量: 311.12900
• PSA: 61.72000
• LogP: 3.47600
• 折射率: 1.604

合成路线

18507-09-0 ~% 10476-53-6

文献：Oatis Jr.; Russell; Knapp; Walle Journal of Medicinal Chemistry, 1981 , vol. 24, # 3 p. 309 - 314

2461-42-9 ~% 10476-53-6

文献：Narimatsu, Shizuo; Arai, Takayuki; Watanabe, Toshiyuki; Masubuchi, Yasuhiro; Horie, Toshiharu; Suzuki, Tokuji; Ishikawa, Tsutomu; Tsutsui, Michio; Kumagai, Yoshito; Cho, Arthur K. Chemical Research in Toxicology, 1997 , vol. 10, # 3 p. 289 - 295

90-15-3 ~% 10476-53-6

文献：Narimatsu, Shizuo; Arai, Takayuki; Watanabe, Toshiyuki; Masubuchi, Yasuhiro; Horie, Toshiharu; Suzuki, Tokuji; Ishikawa, Tsutomu; Tsutsui, Michio; Kumagai, Yoshito; Cho, Arthur K. Chemical Research in Toxicology, 1997 , vol. 10, # 3 p. 289 - 295

525-66-6 ~% 10476-53-6

文献：Fantuzzi, Andrea; Mak, Lok Hang; Capria, Ennio; Dodhia, Vikash; Panicco, Paola; Collins, Stephen; Gilardi, Gianfranco Analytical Chemistry, 2011 , vol. 83, # 10 p. 3831 - 3839

84-85-5 ~% 10476-53-6

文献：Oatis Jr.; Russell; Knapp; Walle Journal of Medicinal Chemistry, 1981 , vol. 24, # 3 p. 309 - 314

14133-79-0 ~% 10476-53-6

文献：Crowther,A.F.; Smith,L.H. Journal of Medicinal Chemistry, 1968 , vol. 11, # 5 p. 1009 - 1013

318-98-9 ~% 10476-53-6 30200-48-7 10476-54-7 详细

文献：Ghabrial; Nand; Stead; Smallwood; Morgan Journal of Pharmaceutical Sciences, 1994 , vol. 83, # 7 p. 931 - 936

上下游产品

上游产品  6
18507-09-0 2461-42-9 90-15-3 525-66-6
84-85-5 318-98-9
下游产品  1
130-15-4