88611-67-0

• 常用中文名：N1-(5-氧-5,6,7,8-四氢萘酚-2-基)乙酰胺
• 常用英文名：N1-(5-oxo-5,6,7,8-tetrahydronaphthalen-2-yl)acetamide
• CAS号：88611-67-0
• 分子式：C₁₂H₁₃NO₂
• 分子量：203.237
• 发布时间：2018-11-24 12:53:59
• 更新时间：2024-01-02 16:16:22

名称

• 中文名: N-(5-氧代-5,6,7,8-四氢萘酚-2-基)乙酰胺
• 英文名: N-(5-Oxo-5,6,7,8-tetrahydronaphthalen-2-yl)acetamide
• 中文别名: N1-(5-氧-5,6,7,8-四氢萘酚-2-基)乙酰胺; 6-乙酰氨基-1,2,3,4-四氢萘-1-酮
• 英文别名: N-(5-Oxo-5,6,7,8-tetrahydronaphthalen-2-yl)acetamide; N-(5-oxo-7,8-dihydro-6H-naphthalen-2-yl)acetamide; Acetamide, N-(5,6,7,8-tetrahydro-5-oxo-2-naphthalenyl)-; N-(5-Oxo-5,6,7,8-tetrahydro-2-naphthalenyl)acetamide

物化性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 439.6±34.0 °C at 760 mmHg
• 熔点: 127-129ºC
• 分子式: C₁₂H₁₃NO₂
• 分子量: 203.237
• 闪点: 193.4±25.8 °C
• 精确质量: 203.094635
• PSA: 46.17000
• LogP: 1.99
• 蒸汽压: 0.0±1.1 mmHg at 25°C
• 折射率: 1.609
• 储存条件: 室温，干燥

MSDS

Name: N1-(5-oxo-5 6 7 8-tetrahydronaphthalen-2-yl)acetamide Material Safety Data Sheet Synonym: CAS: 88611-67-0 Section 1 - Chemical Product MSDS Name:N1-(5-oxo-5 6 7 8-tetrahydronaphthalen-2-yl)acetamide Material Safety Data Sheet Synonym: Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS CAS# Chemical Name content EINECS# 88611-67-0 N1-(5-Oxo-5,6,7,8-tetrahydronaphthalen >97% unlisted Hazard Symbols: XN Risk Phrases: 22 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW Harmful if swallowed. Potential Health Effects Eye: May cause eye irritation. Skin: May cause skin irritation. May be harmful if absorbed through the skin. Ingestion: Harmful if swallowed. May cause irritation of the digestive tract. Inhalation: May cause respiratory tract irritation. May be harmful if inhaled. Chronic: Not available. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Get medical aid. Wash mouth out with water. Inhalation: Remove from exposure and move to fresh air immediately. Notes to Physician: Treat symptomatically and supportively. Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Section 7 - HANDLING and STORAGE Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Storage: Store in a cool, dry place. Store in a tightly closed container. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 88611-67-0: Personal Protective Equipment Eyes: Not available. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Solid Color: off-white Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: 124 - 126 deg C Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: C12H13NO2 Molecular Weight: 203 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Not available. Conditions to Avoid: Incompatible materials. Incompatibilities with Other Materials: Oxidizing agents, reducing agents, acids, bases. Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 88611-67-0 unlisted. LD50/LC50: Not available. Carcinogenicity: N1-(5-Oxo-5,6,7,8-tetrahydronaphthalen-2-yl)acetamide - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Shipping Name: Not regulated. Hazard Class: UN Number: Packing Group: IMO Shipping Name: Not regulated. Hazard Class: UN Number: Packing Group: RID/ADR Shipping Name: Not regulated. Hazard Class: UN Number: Packing group: Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: XN Risk Phrases: R 22 Harmful if swallowed. Safety Phrases: S 24/25 Avoid contact with skin and eyes. WGK (Water Danger/Protection) CAS# 88611-67-0: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 88611-67-0 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 88611-67-0 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A

安全

• 危害码 (欧洲): Xn: Harmful;
• 风险声明 (欧洲): R22
• 安全声明 (欧洲): 24/25
• 海关编码: 2924299090

合成路线

3470-53-9 108-24-7 ~% 88611-67-0

文献：WO2008/76336 A2, ; Page/Page column 78 ; WO 2008/076336 A2

50878-03-0 ~% 88611-67-0

文献：Journal of Medicinal Chemistry, , vol. 19, # 4 p. 472 - 475

14714-31-9 ~% 88611-67-0

文献：Bioorganic and Medicinal Chemistry, , vol. 19, # 18 p. 5539 - 5552

2051-95-8 ~% 88611-67-0

文献：Bioorganic and Medicinal Chemistry, , vol. 19, # 18 p. 5539 - 5552

6328-00-3 ~% 88611-67-0

文献：Bioorganic and Medicinal Chemistry, , vol. 19, # 18 p. 5539 - 5552

上下游产品

上游产品  5
3470-53-9 108-24-7 50878-03-0 2051-95-8
6328-00-3
下游产品  3
3470-53-9 66361-67-9 121866-04-4

海关

海关编码	2924299090
中文概述	2924299090. 其他环酰胺（包括环氨基甲酸酯）（包括其衍生物以及他们的盐）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%
申报要素	品名, 成分含量, 用途, 包装
Summary	2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%