21717-29-3

• 常用中文名：6-乙基吡啶-2-胺
• 常用英文名：6-Ethyl-2-pyridinamine
• CAS号：21717-29-3
• 分子式：C₇H₁₀N₂
• 分子量：122.168
• 相关类别： 医药中间体 杂环化合物 吡啶类化合物 乙基吡啶
• 发布时间：2018-04-04 08:00:00
• 更新时间：2024-01-08 19:25:37
• 下载msds

名称

• 中文名: 2-氨基-6-乙基吡啶
• 英文名: 6-ethylpyridin-2-amine
• 中文别名: 6-乙基吡啶-2-胺
• 英文别名: 2-Pyridinamine,6-ethyl; MFCD00218265; 2-Amino-6-ethylpyridine; 6-ethyl-amine; 2-Pyridinamine, 6-ethyl-; 6-Ethylpyridin-2-Amine; 6-Ethylpyridin-2-yl amine; 6-Ethyl-2-pyridinamine; 4,6-dichloro-pyridazine-3-carboxylic acid ethyl ester; 6-amino-2-ethylpyridine; 6-ethyl-2-pyridylamine; EINECS 244-540-7

物化性质

• 密度: 1.0±0.1 g/cm3
• 沸点: 218.8±20.0 °C at 760 mmHg
• 分子式: C₇H₁₀N₂
• 分子量: 122.168
• 闪点: 108.5±9.0 °C
• 精确质量: 122.084396
• PSA: 38.91000
• LogP: 1.61
• 蒸汽压: 0.1±0.4 mmHg at 25°C
• 折射率: 1.561
• 储存条件:

  保持贮藏器密封

  放入紧密的贮藏器内，储存在阴凉，干燥的地方

• 稳定性:

  如果遵照规格使用和储存则不会分解

  避免接触氧化物，酸，酸性氯化物，酸酐
• 分子结构:

  1、 摩尔折射率：38.12

  2、 摩尔体积(m³/mol)：117.7

  3、 等张比容(90.2K)：303.8

  4、 表面张力(dyne/cm)：44.3

  5、 极化率(10-24cm³)：15.11

• 计算化学:

  1、疏水参数计算参考值（XlogP）:1.5

  2、氢键供体数量：2

  3、氢键受体数量：1

  4、可旋转化学键数量:1

  5、互变异构体数量：7

  6、拓扑分子极性表面积（TPSA）:40.2

  7、重原子数量：9

  8、表面电荷：0

  9、复杂度：83

  10、同位素原子数量：0

  11、确定原子立构中心数量：0

  12、不确定原子立构中心数量：0

  13、确定化学键立构中心数量：0

  14、不确定化学键立构中心数量：0

  15、共价键单元数量：1

• 更多:

  1.性状：未确定

  2.密度（g/mL,25/4℃）：未确定

  3.相对蒸汽密度（g/mL,空气=1）：未确定

  4.熔点（ºC）：未确定

  5.沸点（ºC,常压）：未确定

  6.沸点（ºC,5.2kPa）：未确定

  7.折射率：1.5680

  8.闪点（ºC）：未确定

  9.比旋光度（º）：未确定

  10.自燃点或引燃温度（ºC）：未确定

  11.蒸气压（kPa,25ºC）：未确定

  12.饱和蒸气压（kPa,60ºC）：未确定

  13.燃烧热（KJ/mol）：未确定

  14.临界温度（ºC）：未确定

  15.临界压力（KPa）：未确定

  16.油水（辛醇/水）分配系数的对数值：未确定

  17.爆炸上限（%,V/V）：未确定

  18.爆炸下限（%,V/V）：未确定

  19.溶解性：未确定

MSDS

Name: 6-Ethylpyridin-2-amine 97% Material Safety Data Sheet Synonym: CAS: 21717-29-3 Section 1 - Chemical Product MSDS Name:6-Ethylpyridin-2-amine 97% Material Safety Data Sheet Synonym: Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS CAS# Chemical Name content EINECS# 21717-29-3 6-Ethylpyridin-2-amine 97% 244-540-7 Hazard Symbols: XN Risk Phrases: 20/21/22 Section 3 - HAZARDS IDENTIFICATION EMERGENCY OVERVIEW Harmful by inhalation, in contact with skin and if swallowed. Potential Health Effects Eye: May cause eye irritation. Skin: May cause skin irritation. Harmful if absorbed through the skin. Ingestion: Harmful if swallowed. May cause irritation of the digestive tract. Inhalation: Harmful if inhaled. May cause respiratory tract irritation. Chronic: Not available. Section 4 - FIRST AID MEASURES Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Ingestion: Get medical aid. Wash mouth out with water. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Section 5 - FIRE FIGHTING MEASURES General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or chemical foam. Section 6 - ACCIDENTAL RELEASE MEASURES General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Absorb spill with inert material (e.g. vermiculite, sand or earth), then place in suitable container. Vacuum or sweep up material and place into a suitable disposal container. Section 7 - HANDLING and STORAGE Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes. Storage: Store in a cool, dry place. Store in a tightly closed container. Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION Engineering Controls: Use adequate ventilation to keep airborne concentrations low. Exposure Limits CAS# 21717-29-3: Personal Protective Equipment Eyes: Not available. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced. Section 9 - PHYSICAL AND CHEMICAL PROPERTIES Physical State: Solid or liquid Color: Not available. Odor: Not available. pH: Not available. Vapor Pressure: Not available. Viscosity: Not available. Boiling Point: Not available. Freezing/Melting Point: Not available. Autoignition Temperature: Not available. Flash Point: Not available. Explosion Limits, lower: Not available. Explosion Limits, upper: Not available. Decomposition Temperature: Solubility in water: Specific Gravity/Density: Molecular Formula: C7H10N2 Molecular Weight: 122 Section 10 - STABILITY AND REACTIVITY Chemical Stability: Not available. Conditions to Avoid: Incompatible materials. Incompatibilities with Other Materials: Acids, oxidizing agents. Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide, acrid smoke and fumes. Hazardous Polymerization: Has not been reported Section 11 - TOXICOLOGICAL INFORMATION RTECS#: CAS# 21717-29-3 unlisted. LD50/LC50: Not available. Carcinogenicity: 6-Ethylpyridin-2-amine - Not listed by ACGIH, IARC, or NTP. Section 12 - ECOLOGICAL INFORMATION Section 13 - DISPOSAL CONSIDERATIONS Dispose of in a manner consistent with federal, state, and local regulations. Section 14 - TRANSPORT INFORMATION IATA Shipping Name: TOXIC LIQUID, ORGANIC, N.O.S.* Hazard Class: 6.1 UN Number: 2810 Packing Group: III IMO Shipping Name: TOXIC LIQUID, ORGANIC, N.O.S. Hazard Class: 6.1 UN Number: 2810 Packing Group: III RID/ADR Shipping Name: TOXIC LIQUID, ORGANIC, N.O.S. Hazard Class: 6.1 UN Number: 2810 Packing group: III Section 15 - REGULATORY INFORMATION European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: XN Risk Phrases: R 20/21/22 Harmful by inhalation, in contact with skin and if swallowed. Safety Phrases: S 36/37 Wear suitable protective clothing and gloves. WGK (Water Danger/Protection) CAS# 21717-29-3: No information available. Canada None of the chemicals in this product are listed on the DSL/NDSL list. CAS# 21717-29-3 is not listed on Canada's Ingredient Disclosure List. US FEDERAL TSCA CAS# 21717-29-3 is not listed on the TSCA inventory. It is for research and development use only. SECTION 16 - ADDITIONAL INFORMATION N/A

毒性和生态

生态学数据: 对水是稍微危害的，若无政府许可，勿将材料排入周围环境

安全

• 危害码 (欧洲): Xi: Irritant;
• 风险声明 (欧洲): R36/37/38
• 安全声明 (欧洲): S26-S36/37/39
• 危险品运输编码: UN2810
• 包装等级: III
• 危险类别: 6.1
• 海关编码: 2933399090

合成路线

95337-73-8 ~86% 21717-29-3

文献：Bruekelman, Stephen P.; Leach, (Miss) Susan E.; Meakins, G. Denis; Tirel, Malcolm D. Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1984 , p. 2801 - 2807

45644-21-1 557-20-0 ~% 21717-29-3

文献：WO2011/112995 A1, ; Page/Page column 69 ; WO 2011/112995 A1

100-71-0 ~% 21717-29-3

文献：Journal of Organic Chemistry, , vol. 23, p. 67

32570-89-1 ~% 21717-29-3

文献：Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 2801 - 2807

32570-89-1 74-88-4 ~% 21717-29-3

文献：Journal of the Chemical Society, Chemical Communications, , # 14 p. 800 - 801

上下游产品

上游产品  6
95337-73-8 45644-21-1 557-20-0 100-71-0
32570-89-1 74-88-4
下游产品  5
686290-03-9 83004-13-1 848360-94-1 848360-99-6
59146-66-6

海关

海关编码	2933399090
中文概述	2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%