83-74-9

• 常用中文名：伊波加因
• 常用英文名：Ibogaine
• CAS号：83-74-9
• 分子式：C₂₀H₂₆N₂O
• 分子量：310.433
• 相关类别： 天然产物 生物碱
• 发布时间：2018-06-24 08:20:08
• 更新时间：2024-01-10 13:10:53

名称

• 中文名: 伊博格碱
• 英文名: ibogaine
• 英文别名: 12-methoxy-ibogamin; (-)-Ibogaine; 12-Methoxyibogamine; Endabuse; Ibogaine (8CI); (–)-12-Methoxyibogamine; Ibogamine,12-methoxy; Ibogamine, 12-methoxy-; Ibogain; Ibogaine; MFCD03265619

物化性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 484.2±40.0 °C at 760 mmHg
• 熔点: 152-153°
• 分子式: C₂₀H₂₆N₂O
• 分子量: 310.433
• 闪点: 246.6±27.3 °C
• 精确质量: 310.204498
• PSA: 28.26000
• LogP: 4.56
• 外观性状: 粉末
• 蒸汽压: 0.0±1.2 mmHg at 25°C
• 折射率: 1.643
• 储存条件: 2-8℃，干燥，密闭

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : NH6918615 CHEMICAL NAME : Ibogamine, 12-methoxy- CAS REGISTRY NUMBER : 83-74-9 LAST UPDATED : 199806 DATA ITEMS CITED : 3 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 327 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 21,1109,1996 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 145 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 21,1109,1996 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - guinea pig DOSE/DURATION : 82 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : DRFUD4 Drugs of the Future. (J.R. Prous, S.A., Apartado de Correos 540, 08080 Barcelona, Spain) V.1- 1975/76- Volume(issue)/page/year: 21,1109,1996

安全

• 危害码 (欧洲): F,T
• 风险声明 (欧洲): 11-23/24/25-39/23/24/25
• 安全声明 (欧洲): 7-16-36/37-45
• 危险品运输编码: UN 1544
• 包装等级: III
• 危险类别: 6.1(b)

合成路线

510-22-5 ~% 83-74-9

文献：US2813873 , ; Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, , vol. 241, p. 986 Helvetica Chimica Acta, , vol. 42, p. 1572,1577 Annales de Chimie (Cachan, France), , vol. <13>4, p. 303,319,344

2637-13-0 ~% 83-74-9

文献：US2877229 , ;

113950-91-7 ~% 83-74-9

文献：Experientia, , vol. 15, p. 456

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