192569-17-8

• 常用中文名：11α-羟基坎利酮
• 常用英文名：11α-Hydroxy Canrenone
• CAS号：192569-17-8
• 分子式：C₂₂H₂₈O₄
• 分子量：356.455
• 发布时间：2018-05-28 08:00:00
• 更新时间：2026-07-03 21:33:08

名称

• 中文名: 11-alpha-羟基坎利酮
• 英文名: 11α-Hydroxy Canrenone
• 中文别名: 依普利酮杂质7; 11A-羟基坎利酮 依普利酮中间体; 11A-经基坎利酮; 11Α-羟基刊利酮; 11-Alpha-羟基坎利酮; 11-ALPHA-羟基坎利酮,依普利酮中间体; 11-阿法羟基坎利酮; (8S,9S,10R,11R,13S,14S,17R)-11-羟基-10,13-二甲基螺 [2,8,9,11,12,14,15,16-八氢-1H-环戊二烯并 [A] 菲-17,5-恶烷]-2,3-二酮; 依普利酮杂质24; 11Α-羟基坎利酮; 依普利酮杂质11ΑHYDROXY CANRENONE; 依普利酮- 11-ALPHA-HYDROXY CANRENONE杂质; 11ALPHA-羟基刊利酮; 依普利酮杂质-11-Α-羟基坎利酮; 11-OH- 坎利酮; 11Α-羟基-坎利酮; 11Α-羟基坎列酮; 11羟基坎利酮(依普利酮中间体)
• 英文别名: 11α-hydroxyl canrenone; Eplerenone Impurity 9; 11A-hydroxykanolone; Pregna-4,6-diene-21-cboxylic acid, 11,17-dihydroxy-3-oxo-, γ-lactone, (11α,17α); 3-(3-OXO-11A,17SS-DIHYDROXY-4,6-DIENE-PREGNA-17A-YL)PROPANOIC ACID LACTONE; lerenone intermediate 11a-Hydroxycanrenone; lerenone Intermediates; lerenone IMpurity - 11-alpha-Hydroxy Canrenone; (8S,9S,10R,11R,13S,14S,17R)-11-hydroxy-10,13-dimethylspiro[2,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthrene-17,5'-oxolane]-2',3-dione; 11-alpha-Hydroxycvenone; 11α-Hydroxycvenone; 11α-Hydroxycanrenone(A0); 11-α-Hydroxycarvenone; 3-(3-oxo-11a,17-dihydroxy-4,6-diene-pregna-17a-yl)propanoicacidlactone; 11-alpha-Hydroxyc; lerenone Impurity 24; 11-alpha-Hydroxycvene; (8S,9S,10R,11R,13S,14S,17R)-11-Hydroxy-10,13-dimethyl-1,8,9,10,11,12,13,14,15,16-decahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-3,5'(2H,4'H)-dione; 11-ALPHA-HYDROXY-CNRENONE; lerenone 11-alpha-Hydroxy Canrenone Impurity; MFCD09038746; (11α,17α)-11,17-Dihydroxy-3-oxopregna-4,6-diene-21-cboxylic Acid; 11-ALPHA-HYDROXYCVENONE 192-8; 11Alpha-HydroxyCanrenone; 11a-Hydroxy Canrenone; lerenone Canrenone Imp; (11a,17a)-11,17-dihydroxy-3-oxo-pregna-4,6-diene-21-cboxylic acid; 11-HYDROXY-CANRENONE; 11α-Hydroxy canrenon

物化性质

• 密度: 1.3±0.1 g/cm3
• 沸点: 584.7±50.0 °C at 760 mmHg
• 熔点: 232-234°C
• 分子式: C₂₂H₂₈O₄
• 分子量: 356.455
• 闪点: 207.3±23.6 °C
• 精确质量: 356.198761
• PSA: 63.60000
• LogP: 1.21
• 外观性状: 黄色结晶固体
• 蒸汽压: 0.0±3.7 mmHg at 25°C
• 折射率: 1.598
• 储存条件: -20?C Freezer

合成路线

976-71-6 ~89% 192569-17-8

文献：G.D. SEARLE and CO. Patent: EP1223174 A2, 2002 ; Location in patent: Example 16 ;

976-71-6 ~% 192569-17-8 1363502-03-7

文献：Chinese Chemical Letters, , vol. 23, # 3 p. 313 - 316

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