100134-82-5

• 常用中文名：(1-氰基-1-甲基乙基)氨基甲酸苄酯
• 常用英文名：Benzyl (1-cyano-1-methylethyl)carbamate
• CAS号：100134-82-5
• 分子式：C₁₂H₁₄N₂O₂
• 分子量：218.25200
• 发布时间：2018-12-29 18:43:35
• 更新时间：2026-07-13 13:53:41

名称

• 中文名: (1-氰基-1-甲基乙基)氨基甲酸苄酯
• 英文名: Benzyl (1-cyano-1-methylethyl)carbamate
• 中文别名: 雷特格韦中间体1; N-(1-氰基-1-甲基乙基)氨基甲酸苄酯; 2-(CBZ-氨基)-2-甲基丙腈; (2-氰基丙烷-2-基)氨基甲酸苄酯; [1-氰基-1-甲基乙基]氨基甲酸苄酯; (1-氰基-1-甲基乙基)氨基甲酸苄酯(雷特格韦中间体)
• 英文别名: Benzyl-[1-cyano-1-methylethyl]cbamate (CAS No.100-5); Cbamicacid, N-(1-cyano-1-methylethyl)-, phenylmethyl ester; N-(2-cyanopropan-2-yl)cbamic acid (phenylmethyl) ester; (CYANO-DIMETHYL-METHYL)CBAMIC ACID BENZYL ESTER; Ralteavir Intermediate 1; BENZYL [1-CYANO-1-METHYLETHYL]CBAMATE; benzyl 2-cyanopropan-2-ylcbaMate; Benzyl N-(1-cyano-1-methylethyl)cbamate; Ralteavir I; N-(1-cyano-1-methylethyl)-, phenylmethyl ester; benzyl N-(2-cyanopropan-2-yl)carbamate; TIANFU-CHEM - BENZYL [1-CYANO-1-METHYLETHYL]CBAMATE; benzyl N-(2-cyanopropan-2-yl)cbamate; Benzyl (1-cyano-1-methylethyl); 2-(Cbz-amino)-2-methylpropanenitrile

物化性质

• 密度: 1.124 g/cm3
• 沸点: 381.6ºC at 760 mmHg
• 分子式: C₁₂H₁₄N₂O₂
• 分子量: 218.25200
• 闪点: 184.6ºC
• 精确质量: 218.10600
• PSA: 62.12000
• LogP: 2.60588
• 外观性状: 无色固体
• 折射率: 1.526

安全

• 海关编码: 2926909090

合成路线

501-53-1 19355-69-2 ~99% 100134-82-5

文献：Pace, Paola; Di Francesco, M. Emilia; Gardelli, Cristina; Harper, Steven; Muraglia, Ester; Nizi, Emanuela; Orvieto, Federica; Petrocchi, Alessia; Poma, Marco; Rowley, Michael; Scarpelli, Rita; Laufer, Ralph; Paz, Odalys Gonzalez; Monteagudo, Edith; Bonelli, Fabio; Hazuda, Daria; Stillmock, Kara A.; Summa, Vincenzo Journal of Medicinal Chemistry, 2007 , vol. 50, # 9 p. 2225 - 2239

81587-18-0 ~96% 100134-82-5

文献：Wang, Ziwen; Wang, Mingxiao; Yao, Xue; Li, Yue; Qiao, Wentao; Geng, Yunqi; Liu, Yuxiu; Wang, Qingmin European Journal of Medicinal Chemistry, 2012 , vol. 50, p. 361 - 369

15030-72-5 ~% 100134-82-5

文献：European Journal of Medicinal Chemistry, , vol. 50, p. 361 - 369

501-53-1 ~% 100134-82-5

文献：European Journal of Medicinal Chemistry, , vol. 50, p. 361 - 369

19355-69-2 ~% 100134-82-5

文献：Chemische Berichte, , vol. 89, p. 1185,1193 Chemische Berichte, , vol. 90, p. 451

上下游产品

上游产品  4
501-53-1 19355-69-2 81587-18-0 15030-72-5
下游产品  2
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海关

海关编码	2926909090
中文概述	2926909090 其他腈基化合物. 增值税率:17.0% 退税率:9.0% 监管条件:无 最惠国关税:6.5% 普通关税:30.0%
申报要素	品名, 成分含量, 用途
Summary	HS:2926909090 other nitrile-function compounds VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%