17758-52-0

• 常用中文名：5-甲基嘧啶-4-醇
• 常用英文名：4-Hydroxy-5-methylpyrimidine
• CAS号：17758-52-0
• 分子式：C₅H₆N₂O
• 分子量：110.114
• 相关类别： 医药中间体 杂环化合物 嘧啶类化合物 甲基嘧啶
• 发布时间：2018-06-13 17:15:59
• 更新时间：2024-01-24 15:18:54

名称

• 中文名: 5-甲基-4-羟基嘧啶
• 英文名: 5-methyl-1H-pyrimidin-6-one
• 中文别名: 4-羟基-5-甲基嘧啶; 5-甲基嘧啶-4-醇
• 英文别名: 5-Methyl-4-hydroxypyrimidine; 4-Pyrimidinol, 5-methyl-; 5-Methyl-4-pyrimidinol; 4-oxo-6-methylpyrimidine; 5-methylpyrimidin-4-ol; 5-Methyl-4(1H)-pyrimidinone; 5-methyl-3H-pyrimidin-4-one; 5-Methyl-3H-pyrimidin-4-on; 4-Pyrimidinol,5-methyl; 5-methyl-4(3H)-pyrimidinone; 4-Hydroxy-5-methylpyrimidine; 4-Oxy-5-methylpyrimidin

物化性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 229.7±20.0 °C at 760 mmHg
• 分子式: C₅H₆N₂O
• 分子量: 110.114
• 闪点: 92.7±21.8 °C
• 精确质量: 110.048012
• PSA: 46.01000
• LogP: -0.66
• 蒸汽压: 0.0±0.5 mmHg at 25°C
• 折射率: 1.557
• 储存条件: 2-8°C

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : UW6850000 CHEMICAL NAME : 4-Pyrimidinol, 5-methyl- CAS REGISTRY NUMBER : 17758-52-0 LAST UPDATED : 198303 DATA ITEMS CITED : 1 MOLECULAR FORMULA : C5-H6-N2-O MOLECULAR WEIGHT : 110.13 WISWESSER LINE NOTATION : T6N CNJ DQ E1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 213 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA, 1255 Howard St., San Francisco, CA 94103) V.6- 1958- Volume(issue)/page/year: 11,495,1963

安全

• 危害码 (欧洲): Xi

合成路线

636-26-0 ~97% 17758-52-0

文献：CANCER RESEARCH TECHNOLOGY LIMITED; McDONALD, Edward; BLAGG, Julian; PICHOWICZ, Mark; CRUMPLER, Simon Ross Patent: WO2010/41054 A1, 2010 ; Location in patent: Page/Page column 40-41 ;

636-26-0 ~0% 17758-52-0 65-71-4

文献：Matsui; Kamiya; Kawamura; Shibata; Muramatsu Bulletin of the Chemical Society of Japan, 1989 , vol. 62, # 9 p. 2939 - 2941

636-26-0 7722-84-1 ~% 17758-52-0

文献：Journal of the American Chemical Society, , vol. 59, p. 526,527

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