1035-77-4

• 常用中文名：17-Beta-雌二醇 3-甲醚
• 常用英文名：Estra-1,3,5(10)-trien-17-ol,3-methoxy-, (17b)
• CAS号：1035-77-4
• 分子式：C₁₉H₂₆O₂
• 分子量：286.40900
• 发布时间：2018-12-16 18:17:24
• 更新时间：2026-07-01 07:31:35

名称

• 中文名: 17-Beta-雌二醇 3-甲醚
• 英文名: (8R,9S,13S,14S,17S)-3-methoxy-13-methyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-ol
• 中文别名: Β-雌二醇 3-甲醚 溶液; 1,3,5-雌三烯-3,17Β-二醇 3-甲醚; 普罗雌烯杂质9; 炔雌醇杂质15; 17B-羟基-3-甲氧基-1,3,5-雌三烯; 17Β-羟基-3-甲氧基-1,3,5-雌三烯
• 英文别名: 3-Methoxy-estra-1,3,5-triene-17β-ol; 1,3,5-Estratriene-3,17β-diol 3-methyl ether; 3-methoxyoestra-1,3,5-trien-17-β-ol; BETA-ESTRADIOL 3-METHYL ETHER; 1,3,5-ESTRATRIEN-3,17-BETA-DIOL 3-METHYL ETHER; BETA-ETHYLESTRADIOL 3-METHYL ETHER; 17β-Hydroxy-3-methoxy-1,3,5-estratriene; Estra-1,3,5-trien-17-ol, 3-methoxy-, (17β); Estra-1,3,5-trien-17-ol,3-methoxy-, (17b); 3,17B-ESTRADIOL 3-METHYL ETHER; estradiol3-methylether; 3-methoxy-estra-1,3,5-triene-17-beta-ol; 3-methoxyoestra-1,3,5-trien-17-beta-ol; 1,17-dihydroxy-1,3,5-estratriane-3-methyl ether; BENZOYLOXY 17BETA-ESTROL; β-Estradiol 3-methyl ether solution; 3-methoxy-(17-beta)-estra-5-trien-17-ol; 3-methoxyoestradiol; estradiol-17beta-3-methylether; Promestriene Impurity 9; 5-trien-17-beta-ol,3-methoxy-estra-3; 1,3,5-ESTRATRIENE-3,17BETA-DIOL 3-METHYL ETHER; EINECS 213-858-8; 3-methoxyestra-1,3,5-trien-17-beta-ol; (8R,9S,13S,14S,17S)-3-Methoxy-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthren-17-ol; 17β-Estradiol 3-methyl ether; 3,17BETA-DIHYDROXY-1,3,5-ESTRATRIENE 3-METHYL ETHER; 3-Methoxyestradiol; 17beta-Estradiol 3-methyl ether; 1, 3, 5-ESTRATRIEN-3, 17β-DIOL 3-METHYL ETHER; Oestradiol 3-methyl ether; 3-Methoxyestra-1,3,5-trien-17β-ol; [14C]-3-Methoxyestradiol; 3-Methoxyestra-1,2,4-triene-17β-ol; [3H]-3-Methoxyestradiol; 3-Methoxy-1,3,5-estratrien-17β-ol; 3-methoxyoestra-1,3,5-trien-17--ol; 3-O-Methyl Estradiol; Estradiol-17beta-3-methyl ether; 3-Methoxyoestradiol; 3,17β-Dihydroxy-1,3,5-estratriene; 3-methoxyestra-1,3,5(10)-trien-17-|A-ol; Estradiol 3-methyl ether

物化性质

• 密度: 1.109 g/cm3
• 沸点: 428.8ºC at 760 mmHg
• 分子式: C₁₉H₂₆O₂
• 分子量: 286.40900
• 闪点: 187.9ºC
• 精确质量: 286.19300
• PSA: 29.46000
• LogP: 3.91220
• 蒸汽压: 4.07E-08mmHg at 25°C
• 折射率: 1.566

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : KG7732000 CHEMICAL NAME : Estra-1,3,5(10)-trien-17-beta-ol, 3-methoxy- CAS REGISTRY NUMBER : 1035-77-4 LAST UPDATED : 198910 DATA ITEMS CITED : 5 MOLECULAR FORMULA : C19-H26-O2 MOLECULAR WEIGHT : 286.45 WISWESSER LINE NOTATION : L E5 B666TTT&J E1 FQ OO1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous DOSE : 2 mg/kg SEX/DURATION : male 1 day(s) pre-mating TOXIC EFFECTS : Reproductive - Paternal Effects - testes, epididymis, sperm duct Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland, accessory glands REFERENCE : ACENA7 Acta Endocrinologica (Copenhagen). (Periodica, Skolegade 12 E, DK-2500 Valby, Denmark) V.1- 1948- Volume(issue)/page/year: 49,193,1965 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous DOSE : 2500 ug/kg SEX/DURATION : female 1 day(s) pre-mating TOXIC EFFECTS : Reproductive - Maternal Effects - ovaries, fallopian tubes Reproductive - Fertility - other measures of fertility REFERENCE : ACENA7 Acta Endocrinologica (Copenhagen). (Periodica, Skolegade 12 E, DK-2500 Valby, Denmark) V.1- 1948- Volume(issue)/page/year: 49,193,1965 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous DOSE : 132 ug/kg SEX/DURATION : female 3 day(s) pre-mating TOXIC EFFECTS : Reproductive - Fertility - other measures of fertility REFERENCE : ACENA7 Acta Endocrinologica (Copenhagen). (Periodica, Skolegade 12 E, DK-2500 Valby, Denmark) V.1- 1948- Volume(issue)/page/year: 47,444,1964 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous DOSE : 1050 ug/kg SEX/DURATION : female 3-9 day(s) after conception TOXIC EFFECTS : Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea) REFERENCE : ACENA7 Acta Endocrinologica (Copenhagen). (Periodica, Skolegade 12 E, DK-2500 Valby, Denmark) V.1- 1948- Volume(issue)/page/year: 47,444,1964 TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Subcutaneous DOSE : 3 mg/kg SEX/DURATION : female 1 day(s) pre-mating TOXIC EFFECTS : Reproductive - Fertility - other measures of fertility REFERENCE : 85GRAA "The Control of Fertility," Pincus, G., New York, Academic Press, 1965 Volume(issue)/page/year: -,57,1965

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