693287-79-5

• 常用中文名：2-(四氢吡喃-4-基)肼基甲酸叔丁酯
• 常用英文名：1-Boc-2-(4-tetrahydropyranyl)hydrazine
• CAS号：693287-79-5
• 分子式：C₁₀H₂₀N₂O₃
• 分子量：216.27700
• 发布时间：2018-11-30 19:37:20
• 更新时间：2024-01-10 11:43:14

名称

• 中文名: 2-(四氢吡喃-4-基)肼基甲酸叔丁酯
• 英文名: tert-Butyl 2-(tetrahydro-2H-pyran-4-yl)hydrazinecarboxylate
• 中文别名: 2-(四氢-2H-吡喃-4-基)肼羧酸叔丁酯
• 英文别名: tert-butyl N-(oxan-4-ylamino)carbamate

物化性质

• 分子式: C₁₀H₂₀N₂O₃
• 分子量: 216.27700
• 精确质量: 216.14700
• PSA: 59.59000
• LogP: 1.97650
• 储存条件: 室温，干燥

安全

• 海关编码: 2934999090

合成路线

29943-42-8 870-46-2 ~89% 693287-79-5

文献：McDonald, Iain M.; Austin, Carol; Buck, Ildiko M.; Dunstone, David J.; Gaffen, John; Griffin, Eric; Harper, Elaine A.; Hull, Robert A. D.; Kalindjian, S. Barret; Linney, Ian D.; Low, Caroline M. R.; Patel, Dipa; Pether, Michael J.; Raynor, Michelle; Roberts, Sonia P.; Shaxted, Mark E.; Spencer, John; Steel, Katherine I. M.; Sykes, David A.; Wright, Paul T.; Xun, Wei Journal of Medicinal Chemistry, 2007 , vol. 50, # 20 p. 4789 - 4792

693287-78-4 ~99% 693287-79-5

文献：TYROGENEX, INC.; LIANG, Congxin; LI, Zhigang Patent: WO2010/56320 A2, 2010 ; Location in patent: Page/Page column 54 ; WO 2010/056320 A2

29943-42-8 870-46-2 64-19-7 ~0% 1082745-70-7 详细

文献：Pfizer Inc Patent: US2009/30003 A1, 2009 ; Location in patent: Page/Page column 35-36 ; US 20090030003 A1

64-19-7 693287-78-4 ~% 1082745-70-7 693287-79-5

文献：PFIZER INC. Patent: WO2008/139293 A1, 2008 ; Location in patent: Page/Page column 90; 46 ;

29943-42-8 ~% 693287-79-5

文献：Ranatunge, Ramani R.; Augustyniak, Michael; Bandarage, Upul K.; Earl, Richard A.; Ellis, James L.; Garvey, David S.; Janero, David R.; Letts, L. Gordon; Martino, Allison M.; Murty, Madhavi G.; Richardson, Stewart K.; Schroeder, Joseph D.; Shumway, Matthew J.; Tam, S. William; Trocha, A. Mark; Young, Delano V. Journal of Medicinal Chemistry, 2004 , vol. 47, # 9 p. 2180 - 2193

870-46-2 ~% 693287-79-5

文献：Ranatunge, Ramani R.; Augustyniak, Michael; Bandarage, Upul K.; Earl, Richard A.; Ellis, James L.; Garvey, David S.; Janero, David R.; Letts, L. Gordon; Martino, Allison M.; Murty, Madhavi G.; Richardson, Stewart K.; Schroeder, Joseph D.; Shumway, Matthew J.; Tam, S. William; Trocha, A. Mark; Young, Delano V. Journal of Medicinal Chemistry, 2004 , vol. 47, # 9 p. 2180 - 2193

29943-42-8 870-46-2 64-19-7 ~% 90271-04-8 详细

文献：Verhoest, Patrick R.; Fonseca, Kari R.; Hou, Xinjun; Proulx-Lafrance, Caroline; Corman, Michael; Helal, Christopher J.; Claffey, Michelle M.; Tuttle, Jamison B.; Coffman, Karen J.; Liu, Shenpinq; Nelson, Frederick; Kleiman, Robin J.; Menniti, Frank S.; Schmidt, Christopher J.; Vanase-Frawley, Michelle; Liras, Spiros Journal of Medicinal Chemistry, 2012 , vol. 55, # 21 p. 9045 - 9054

上下游产品

上游产品  4
29943-42-8 870-46-2 693287-78-4 64-19-7
下游产品  4
1082745-50-3 1082745-49-0 116312-69-7 1184920-55-5

海关

海关编码	2934999090
中文概述	2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%