597-25-1

• 常用中文名：Dimethyl morpholinophosphoramidate.
• 常用英文名：Dimethyl morpholinophosphoramidate.
• CAS号：597-25-1
• 分子式：C₆H₁₄NO₄P
• 分子量：195.15300
• 发布时间：2017-02-06 06:13:20
• 更新时间：2025-08-25 10:22:22

名称

• 英文名: 4-dimethoxyphosphorylmorpholine
• 英文别名: Dimethyl 4-morpholinylphosphonate; HC 1717; Morpholino-phosphonsaeure-dimethylester; N,N-oxydiethylene-O,O-dimethylphosphoramidate; Dimethylmorpholinophosphonate; morpholin-4-yl-phosphonic acid dimethyl ester; Orthophosphorsaeure-dimethylester-morpholinid; DIMETHYL MORPHOLINOPHOSPHORAMIDATE; Dimethyl morpholino phosphoroamidite; dimethyl morpholin-4-ylphosphonate

物化性质

• 密度: 1.21g/cm3
• 沸点: 246.8ºC at 760 mmHg
• 分子式: C₆H₁₄NO₄P
• 分子量: 195.15300
• 闪点: 103.1ºC
• 精确质量: 195.06600
• PSA: 57.81000
• LogP: 0.65740
• 折射率: 1.454

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : SZ9660000 CHEMICAL NAME : Phosphonic acid, morpholino-, dimethyl ester CAS REGISTRY NUMBER : 597-25-1 BEILSTEIN REFERENCE NO. : 0141995 LAST UPDATED : 199710 DATA ITEMS CITED : 22 MOLECULAR FORMULA : C6-H14-N-O4-P MOLECULAR WEIGHT : 195.18 WISWESSER LINE NOTATION : T6N DOTJ APO&O1&O1 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 5910 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 2370 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 350 mg/kg TOXIC EFFECTS : Lungs, Thorax, or Respiration - other changes TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intramuscular SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 5200 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 3300 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intraperitoneal SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 5 gm/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 400 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intramuscular SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 4800 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - rabbit DOSE/DURATION : 347 mg/kg TOXIC EFFECTS : Lungs, Thorax, or Respiration - cyanosis TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 35 gm/kg/14D-I TOXIC EFFECTS : Related to Chronic Data - death TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 52 gm/kg/13W-I TOXIC EFFECTS : Liver - changes in liver weight Related to Chronic Data - death TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 28 gm/kg/14D-I TOXIC EFFECTS : Related to Chronic Data - death TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 26 gm/kg/13W-I TOXIC EFFECTS : Related to Chronic Data - death TYPE OF TEST : TDLo - Lowest published toxic dose ROUTE OF EXPOSURE : Oral SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 309 gm/kg/2Y-I TOXIC EFFECTS : Tumorigenic - Carcinogenic by RTECS criteria Blood - leukemia TYPE OF TEST : Specific locus test MUTATION DATA TYPE OF TEST : Sister chromatid exchange TEST SYSTEM : Rodent - hamster Ovary DOSE/DURATION : 3 gm/L REFERENCE : NTPTR* National Toxicology Program Technical Report Series. (Research Triangle Park, NC 27709) No.206- Volume(issue)/page/year: NTP-TR-298,1986

安全

• 海关编码: 2934999090

合成路线

102-77-2 121-45-9 ~67% 615-22-5 597-25-1

文献：Brownbridge, P.; Jowett, I. C. Phosphorus and Sulfur and the Related Elements, 1988 , vol. 35, p. 311 - 318

96-36-6 102-77-2 ~82% 597-25-1 149-30-4

文献：Torii, Sigeru; Sayo, Noboru; Tanaka, Hideo Chemistry Letters, 1980 , p. 695 - 698

102-77-2 121-45-9 ~89% 615-22-5 597-25-1 详细

文献：Torii, Sigeru; Sayo, Noboru; Tanaka, Hideo Chemistry Letters, 1980 , p. 695 - 698

110-91-8 813-77-4 ~% 597-25-1

文献：Cheymol et al. Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1959 , vol. 249, p. 1240

67-56-1 7412-25-1 ~% 70531-19-0 597-25-1 详细

文献：Kasparek, Frantisek; Mollin, Jiri Collection of Czechoslovak Chemical Communications, 1980 , vol. 45, # 2 p. 386 - 396

上下游产品

上游产品  7
102-77-2 121-45-9 96-36-6 110-91-8
813-77-4 67-56-1 7412-25-1
下游产品  0

海关

海关编码	2934999090
中文概述	2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%