25162-00-9

• 常用中文名：(+)-尼古丁
• 常用英文名：(+)-Nicotine
• CAS号：25162-00-9
• 分子式：C₁₀H₁₄N₂
• 分子量：162.23200
• 发布时间：2017-04-07 07:54:44
• 更新时间：2026-07-16 19:02:10

名称

• 中文名: (+)-尼古丁
• 英文名: (R)-nicotine
• 中文别名: R-(+)-尼古丁; D-尼古丁; 烟碱杂质11
• 英文别名: R-(+)-Nicotine; 3-[(2R)-1-methylpyrrolidin-2-yl]pyridine; 64 (Beilstein Handbook Reference); (+)-NICOTINE-(+)-DI-P-TOLUOYL TTRATE; Pseudonicotine; 2’-beta-h-nicotine; Pyridine, 3-(1-methyl-2-pyrrolidinyl)-, (R)- (9ci); (+)-NICOTINE-(+)-DI-P-TOLUOYL TTRATE S YNTHETIC; 2'βH-Nicotine; Pyridine, 3-(1-methyl-2-pyrrolidinyl)-, (R); (r)-3-(1-methyl-2-pyrrolidinyl)pyridine; Pyridine, 3-[(2R)-1-methyl-2-pyrrolidinyl]- (9CI); R-(R)-Nicotine; Pyridine, 3-[(2R)-1-methyl-2-pyrrolidinyl]; (R)-3-(1-Methylpyrrolidin-2-yl)pyridine; Leukotriene B4; 6Z,8E,10E,14Z,5S,12R-diHETE; d-nicotine; LTB4; leukotriene B4 ethanol solution; Leukotriene B4 Lipid Maps MS Standard; 2'bH-Nicotine (8CI); Brn

物化性质

• 密度: 1.032g/cm3
• 沸点: 244.4ºC at 760mmHg
• 分子式: C₁₀H₁₄N₂
• 分子量: 162.23200
• 闪点: 101.7ºC
• 精确质量: 162.11600
• PSA: 16.13000
• LogP: 1.78620
• 储存条件: -20°C

毒性和生态

CHEMICAL IDENTIFICATION RTECS NUMBER : QS5260000 CHEMICAL NAME : 2'-beta-H-Nicotine CAS REGISTRY NUMBER : 25162-00-9 BEILSTEIN REFERENCE NO. : 4666243 LAST UPDATED : 199612 DATA ITEMS CITED : 4 MOLECULAR FORMULA : C10-H14-N2 MOLECULAR WEIGHT : 162.26 HEALTH HAZARD DATA ACUTE TOXICITY DATA TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Subcutaneous SPECIES OBSERVED : Rodent - rat DOSE/DURATION : 50 mg/kg TOXIC EFFECTS : Cardiac - pulse rate Vascular - BP elevation not characterized in autonomic section REFERENCE : 85IXA4 "Structure et Activite Pharmacodyanmique des Medicaments du Systeme Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948 Volume(issue)/page/year: -,584,1948 TYPE OF TEST : LD50 - Lethal dose, 50 percent kill ROUTE OF EXPOSURE : Intravenous SPECIES OBSERVED : Rodent - mouse DOSE/DURATION : 6150 ug/kg TOXIC EFFECTS : Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia Lungs, Thorax, or Respiration - dyspnea REFERENCE : NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 84,1,1984 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Unreported SPECIES OBSERVED : Amphibian - frog DOSE/DURATION : 40 mg/kg TOXIC EFFECTS : Cardiac - pulse rate Vascular - BP elevation not characterized in autonomic section REFERENCE : 85IXA4 "Structure et Activite Pharmacodyanmique des Medicaments du Systeme Nerveux Vegetatif," Bovet, D., and F. Bovet-Nitti, New York, S. Karger, 1948 Volume(issue)/page/year: -,584,1948 TYPE OF TEST : LDLo - Lowest published lethal dose ROUTE OF EXPOSURE : Intramuscular SPECIES OBSERVED : Bird - domestic DOSE/DURATION : 25 mg/kg TOXIC EFFECTS : Details of toxic effects not reported other than lethal dose value REFERENCE : PHZOA9 Physiological Zoology. (Univ. of Chicago Press, Journals Div., POB 37005, Chicago, IL 60637) V.1- 1928- Volume(issue)/page/year: 12,238,1939

安全

• 危害码 (欧洲): Xi
• 海关编码: 2933990090

合成路线

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海关

海关编码	2933990090
中文概述	2933990090. 其他仅含氮杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%