69409-02-5

• 常用中文名：N-乙酰天冬酰胺
• 常用英文名：N-[2-(Dimethylamino)ethyl]-3-(acetylamino)-1,8-naphthalenedicarbimide
• CAS号：69409-02-5
• 分子式：C₁₈H₁₉N₃O₃
• 分子量：325.36200
• 发布时间：2016-03-22 10:41:38
• 更新时间：2025-08-27 18:17:15

名称

• 中文名: N-乙酰天冬酰胺
• 英文名: N-[2-[2-(dimethylamino)ethyl]-1,3-dioxobenzo[de]isoquinolin-5-yl]acetamide
• 中文别名: N-乙酰基氨萘非特
• 英文别名: 2-[2-(Dimethylamino)ethyl]-5-(acetylamino)-2,3-dihydro-1H-benzo[de]isoquinoline-1,3-dione; N-[2-(Dimethylamino)ethyl]-3-(acetylamino)-1,8-naphthalenedicbimide; N-[2-[2-(DiMethylaMino)ethyl]-2,3-dihydro-1,3-dioxo-1H-benz[de]isoquinolin-5-yl]acetaMide; Acetamide, N-[2-[2-(dimethylamino)ethyl]-2,3-dihydro-1,3-dioxo-1H-benz[de]isoquinolin-5-yl]; N-Acetylamonafide; 2-[2-(dimethylamino)ethyl]-1,3-dioxo-2,3-dihydro-1H-benzo[de]isoquinoline-5-ylacetamide; N-acetylamonafide; MADE-FA; 5-(Acetylamino)-2-[2-(dimethylamino)ethyl]-1H-benzo[de]isoquinoline-1,3(2H)-dione; MADE-FA 4512

物化性质

• 密度: 1.314g/cm3
• 沸点: 570.339ºC at 760 mmHg
• 分子式: C₁₈H₁₉N₃O₃
• 分子量: 325.36200
• 闪点: 298.73ºC
• 精确质量: 325.14300
• PSA: 74.90000
• LogP: 2.12220
• 折射率: 1.666

合成路线

108-24-7 69408-81-7 ~95% 69409-02-5

文献：Van Quaquebeke, Eric; Mahieu, Tine; Dumont, Patrick; Dewelle, Janique; Ribaucour, Fabrice; Simon, Gentiane; Sauvage, Sebastien; Gaussin, Jean-Francois; Tuti, Jerome; El Yazidi, Mohamed; Van Vynckt, Frank; Mijatovic, Tatjana; Lefranc, Florence; Darro, Francis; Kiss, Robert Journal of Medicinal Chemistry, 2007 , vol. 50, # 17 p. 4122 - 4134

54824-17-8 ~% 69409-02-5

文献：Van Quaquebeke, Eric; Mahieu, Tine; Dumont, Patrick; Dewelle, Janique; Ribaucour, Fabrice; Simon, Gentiane; Sauvage, Sebastien; Gaussin, Jean-Francois; Tuti, Jerome; El Yazidi, Mohamed; Van Vynckt, Frank; Mijatovic, Tatjana; Lefranc, Florence; Darro, Francis; Kiss, Robert Journal of Medicinal Chemistry, 2007 , vol. 50, # 17 p. 4122 - 4134

3027-38-1 ~% 69409-02-5

文献：Van Quaquebeke, Eric; Mahieu, Tine; Dumont, Patrick; Dewelle, Janique; Ribaucour, Fabrice; Simon, Gentiane; Sauvage, Sebastien; Gaussin, Jean-Francois; Tuti, Jerome; El Yazidi, Mohamed; Van Vynckt, Frank; Mijatovic, Tatjana; Lefranc, Florence; Darro, Francis; Kiss, Robert Journal of Medicinal Chemistry, 2007 , vol. 50, # 17 p. 4122 - 4134

61690-44-6 108-00-9 ~84% 69409-02-5

文献：Fernandez Brana; Martinez Sanz; Castellano; et al. European Journal of Medicinal Chemistry, 1981 , vol. 16, # 3 p. 207 - 212

69408-81-7 72-89-9 ~% 69409-02-5

文献：Cui, Lei; Zhong, Ye; Zhu, Weiping; Xu, Yufang; Qian, Xuhong Chemical Communications, 2010 , vol. 46, # 38 p. 7121 - 7123

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