256951-79-8

• 常用中文名：4-氰基-4-(4-氟苯基)哌啶-1-羧酸叔丁酯
• 常用英文名：tert-Butyl 4-cyano-4-(4-fluorophenyl)piperidine-1-carboxylate
• CAS号：256951-79-8
• 分子式：C₁₇H₂₁FN₂O₂
• 分子量：304.359
• 发布时间：2018-11-22 19:21:11
• 更新时间：2024-01-10 10:16:48

名称

• 中文名: 4-氰基-4-(4-氟苯基)哌啶-1-羧酸叔丁酯
• 英文名: tert-butyl 4-cyano-4-(4-fluorophenyl)piperidine-1-carboxylate
• 英文别名: ar2189; 1-Piperidinecarboxylic acid, 4-cyano-4-(4-fluorophenyl)-, 1,1-dimethylethyl ester; 2-Methyl-2-propanyl 4-cyano-4-(4-fluorophenyl)-1-piperidinecarboxylate

物化性质

• 密度: 1.2±0.1 g/cm3
• 沸点: 423.0±45.0 °C at 760 mmHg
• 分子式: C₁₇H₂₁FN₂O₂
• 分子量: 304.359
• 闪点: 209.7±28.7 °C
• 精确质量: 304.158691
• PSA: 53.33000
• LogP: 2.74
• 蒸汽压: 0.0±1.0 mmHg at 25°C
• 折射率: 1.538

安全

• 海关编码: 2933399090

合成路线

459-22-3 118753-70-1 ~60% 256951-79-8

文献：SCHERING CORPORATION Patent: WO2004/4722 A1, 2004 ; Location in patent: Page/Page column 20; 50-51 ; WO 2004/004722 A1

24424-99-5 252002-46-3 ~68% 256951-79-8

文献：ASTRAZENECA AB Patent: WO2004/56771 A1, 2004 ; Location in patent: Page 23 ; WO 2004/056771 A1

24424-99-5 258500-80-0 ~% 256951-79-8

文献：Liu, Jian; Jian, Tianying; Sebhat, Iyassu; Nargund, Ravi Tetrahedron Letters, 2006 , vol. 47, # 29 p. 5115 - 5117

459-22-3 ~% 256951-79-8

文献：Liu, Jian; Jian, Tianying; Sebhat, Iyassu; Nargund, Ravi Tetrahedron Letters, 2006 , vol. 47, # 29 p. 5115 - 5117

55-86-7 ~% 256951-79-8

文献：Liu, Jian; Jian, Tianying; Sebhat, Iyassu; Nargund, Ravi Tetrahedron Letters, 2006 , vol. 47, # 29 p. 5115 - 5117

海关

海关编码	2933399090
中文概述	2933399090. 其他结构含非稠合吡啶环的化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
申报要素	品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%