1020157-01-0

• 常用中文名：三苯甲基奥尔梅沙坦-d6美多西米尔
• 常用英文名：Trityl Olmesartan Medoxomil
• CAS号：1020157-01-0
• 分子式：C₄₈H₄₄N₆O₆
• 分子量：800.90000
• 发布时间：2017-12-31 01:00:19
• 更新时间：2026-08-31 19:39:07

名称

• 中文名: 三苯甲基奥尔梅沙坦-d6美多西米尔
• 英文名: (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 5-(2-hydroxypropan-2-yl)-2-propyl-3-[[4-[2-(2-trityltetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carboxylate
• 中文别名: 奥美沙坦酯杂质N; N2-硝基奥美沙坦酯; N2-三甲基奥美沙坦; (5-甲基-2-氧代-1,3-二噁英-4-基)甲基4-(2-羟基丙烷-2-基)-2-丙基-1-(2'-(2-三苯基-2H-四唑-5-基)-[1,1'-联苯基]-4-基)甲基)-1H-咪唑-5-羧酸盐 (奥美沙坦甲氧肟杂质); 奥美沙坦酯杂质D;N2-硝基奥美沙坦酯; 奥美沙坦甲氧菊杂质D; OLMESTAN MEDOXOMIL 杂质 D; 奥美沙坦酯杂质D(N2-三甲基奥美沙坦酯); 奥美沙坦酯杂质D; (5-甲基-2-氧代-1,3-二氧环戊烯-4-基)甲基4-(1-羟基-1-甲基乙基)-2-丙基-1-[[2'-[2-(三苯基甲基)-2H-四氮唑-5-基]联苯-4-基]甲基]咪唑-5-甲酸酯; 三苯甲基奥尔梅沙坦-D6美多西米尔; N2-三苯甲基奥美沙坦酯; 奥美沙坦酯 杂质D(N2-三苯甲基奥美沙坦酯); OLMESTAN杂质10(奥美沙坦酯杂质D)
• 英文别名: OLMESTAN MEDOXOMIL IMPURITY D (TRITYL); (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 5-(2-hydroxypropan-2-yl)-2-propyl-3-[[4-[2-(2-trityltetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-cboxylate; Olmestan Impurity D (N2-Trityl Olmestan Medoxomil); 1H-Imidazole-5-cboxylic acid, 4-(1-hydroxy-1-methylethyl)-2-propyl-1-[[2'-[2-(triphenylmethyl)-2H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-, (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl ester; Olmestan Medoxomil Impurity N; Olmestan Impurity 10(Olmestan Medoxomil Impurity D); Olmestan Medoxomil Impurity D (N2-TritylOlmestan Medoxomil); (5-methyl-2-oxo-1,3-dioxolen-4-yl)methyl 4-(1-hydroxy-1-methylethyl)-2-propyl-1-[[2'-[2-(triphenylmethyl)-2H-tetrazol-5-yl]biphenyl-4-yl]methyl]imidazole-5-carboxylate; 4-methyl-5-hydroxymethyl-2-oxo-1,3-dioxol-4-ene; 4-(1-Hydroxy-1-methylethyl)-2-propyl-1-[[2'-[2-(triphenylmethyl)-2H-tetrazol-5-yl][1,1'-biphenyl]-4-yl]methyl]-(5-methyl-2-oxo-1,3-d ioxol-4-yl)1H-Imidazole-5-cboxylic acid methyl ester; Olmestan Medoxomil Impurity D; 4-(hydroxymethyl)-5-methyl-1,3-dioxolenone; trityl olmesartan medoxomil; 4-hydroxymethyl-5-methyl-2-oxo-1,3-dioxole; (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 4-(2-hydroxypropan-2-yl)-2-propyl-1-((2'-(2-trityl-2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-imidazole-5-cboxylate; (5-methyl-2-oxo-1,3-dioxolen-4-yl)methyl 4-(1-hydroxy-1-methylethyl)-2-propyl-1-(4-(2-(trityltetrazol-5-yl)phenyl)phenylmethyl)-imidazole-5-carboxylate; 4-hydroxymethyl-5-methyl-1,3-dioxol-2-one; 1,3-Dioxol-2-one,4-(hydroxymethyl)-5-methyl; (5-Methyl-2-oxo-1,3-dioxol-4-yl)methyl 4-(2-hydroxypropan-2-yl)-2-propyl-1-((2'-(2-trityl-2H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-1H-imidazole-5-cboxylate (Olmestan Medoxomil Impurity); trityl olmesartan acetone solvate; (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl alcohol; Olmestan imp D; N2-Trityl OlMestan MedoxoMil

物化性质

• 分子式: C₄₈H₄₄N₆O₆
• 分子量: 800.90000
• 精确质量: 800.33200
• PSA: 151.30000
• LogP: 8.48360

合成路线

752179-89-8 80841-78-7 ~% 1020157-01-0

文献：WO2011/21224 A2, ; Page/Page column 16-17 ;

58954-23-7 ~% 1020157-01-0

文献：Journal of Medicinal Chemistry, , vol. 39, # 1 p. 323 - 338

133051-88-4 ~% 1020157-01-0

文献：Journal of Medicinal Chemistry, , vol. 39, # 1 p. 323 - 338

144689-94-1 ~% 1020157-01-0

文献：Journal of Medicinal Chemistry, , vol. 39, # 1 p. 323 - 338

144689-93-0 ~% 1020157-01-0

文献：Journal of Medicinal Chemistry, , vol. 39, # 1 p. 323 - 338

172875-59-1 ~% 1020157-01-0

文献：Journal of Medicinal Chemistry, , vol. 39, # 1 p. 323 - 338

51802-42-7 ~% 1020157-01-0

文献：Journal of Medicinal Chemistry, , vol. 39, # 1 p. 323 - 338

124750-59-0 ~% 1020157-01-0

文献：WO2011/21224 A2, ;

上下游产品

上游产品  9
752179-89-8 80841-78-7 58954-23-7 133051-88-4
144689-94-1 144689-93-0 172875-59-1 51802-42-7
124750-59-0
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144689-63-4